mlsanityData to 7 Oct 2026

Spectral Dynamics of Semantic Drift in Clinical Multi-Agent Language Model Networks

arXiv 2607.22758 ↗First posted 23 Jul 2026cs.MA cs.AIcited by 0

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

The integration of iterative LLMs within multi-agent diagnostic frameworks requires a rigorous quantitative reevaluation of underlying communication topologies. Frequently used architectural paradigms depend on scale-free or small-world networks, assuming optimal communication efficiency. Our study mathematically dismantles that assumption for semantic data. By mapping multi-agent communication uncertainty trajectories onto a 768-dimensional BioClinicalBERT embedding space via an analytical isotropic variance proxy using Barab'asi--Albert (BA) and Watts--Strogatz (WS) networks, we prove that structural bottlenecks compromise diagnostic safety. Our phase transition matrices illustrate that localized dense cliques confine hallucinated data, preventing global consensus and forcing the system toward a permanent entropy saturation threshold of H∞ ≈ 5.947. As a result, we measure a severe terminal cosine similarity degradation of 53.29%, completely overwriting the original ground-truth. Moreover, the terminal semantic drift reveals a catastrophic variance amplification of 51.81% (ρ = 1.5181) in highly clustered architectures, proving total system unpredictability when compared to ErdHos--R'enyi configurations (ρ = 1.0766). Instead of reducing errors, hub-centric systems autonomously compound localized hallucinations. By introducing dynamic spectral monitoring operating at an O(N3) time complexity and imposing a strict lower bound on algebraic connectivity (λ_2min) via the continuous eigen-decomposition of the graph Laplacian, we present a mathematically rigorous technique to ensure global state diffusion. Securing the reliability of autonomous medical diagnostics necessitates treating topological stability as a non-negotiable quantitative imperative.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 6 of its 20 references that are in the map. First posted on arXiv 23 Jul 2026.

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6 of 20 references.

References · 6

  1. 2023Improving Factuality and Reasoning in Language Models through Multiagent Debatecited by 1,739
  2. 2023CAMEL: Communicative Agents for "Mind" Exploration of Large Language Model Societycited by 1,348
  3. 2019Publicly Available Clinical BERT Embeddingscited by 995
  4. 2023Multi-Agent Collaboration: Harnessing the Power of Intelligent LLM Agentscited by 329
  5. 2025AgentNet: Decentralized Evolutionary Coordination for LLM-based Multi-Agent Systemscited by 86
  6. 2026Conformity Dynamics in LLM Multi-Agent Systems: The Roles of Topology and Self-Social Weightingcited by 8

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  1. 2026Predictive Maps of Multi-Agent Reasoning: A Successor-Representation Spectrum for LLM Communication Topologies
  2. 2025MedMMV: A Controllable Multimodal Multi-Agent Framework for Reliable and Verifiable Clinical Reasoning
  3. 2026MedPrune: Topology-Efficient Multimodal Multi-Agent Communication Evolution for Medical VQA Tasks
  4. 2026MedMASLab: A Unified Orchestration Framework for Benchmarking Multimodal Medical Multi-Agent Systems
  5. 2026Modeling Clinical Concern Trajectories in Language Model Agents
  6. 2025Embeddings to Diagnosis: Latent Fragility under Agentic Perturbations in Clinical LLMs
  7. 2026Agentic AI-based Framework for Mitigating Premature Diagnostic Handoff and Silent Hallucination in Healthcare Applications
  8. 2025Rethinking Multi-Agent Intelligence Through the Lens of Small-World Networks