MamaBench: Benchmarking LLM Robustness in Maternal and Child Health Diagnosis through Counterfactual Clinical Perturbation
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Abstract (arXiv)
Large language models achieve strong scores on medical benchmarks, yet these benchmarks evaluate each question in isolation, providing no measure of whether a system can distinguish clinically similar presentations requiring different interventions. We introduce MamaBench, the first counterfactual benchmark for maternal and paediatric AI: 434 expert-authored clinical narratives in 217 pairs across 371 pathologies, evaluated via the Bias Trap Rate (BTR), the conditional probability that a model fails the counterfactual given success on the base case. We propose Evidence-Anchored RAG (EA-RAG), a three-stage retrieval method that replaces aggregate similarity with an evidence coverage objective through clinical parameter extraction, coverage auditing, and contrastive sub-queries. Across eight configurations of four frontier LLMs, base accuracy overstates robust accuracy by 16-28 percentage points in every model. EA-RAG achieves 20.3% BTR and 65.0% robust accuracy on Claude Sonnet 4.6, a 5.5 percentage point BTR reduction without degrading base accuracy. The residual 20% BTR confirms that counterfactual robustness in clinical AI remains an open challenge. Keywords: counterfactual evaluation, clinical AI, maternal healthcare, retrieval-augmented generation, diagnostic robustness
Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 21 of its 25 references that are in the map. First posted on arXiv 15 Jul 2026.
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References · 21
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9 more
- 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 543
- 2019Learning the Difference that Makes a Difference with Counterfactually-Augmented Datacited by 439
- 2022Demonstrate-Search-Predict: Composing retrieval and language models for knowledge-intensive NLPcited by 318
- 2023Query2doc: Query Expansion with Large Language Modelscited by 149
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- 2026MedEinst: Benchmarking the Einstellung Effect in Medical LLMs through Counterfactual Differential Diagnosiscited by 4
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- 2026mamabench and mamaretrieval: Benchmarks for Evaluating Medical Retrieval-Augmented Generation in Maternal, Neonatal, and Reproductive Health
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