Fine-Grained Vision-Language Pretraining with Organ-Conditioned Pattern Tokens for CT Understanding
On the map: Multimodal LLMs / vision-language models → Medical vision-language models
Abstract (arXiv)
Computed tomography (CT) vision-language pretraining from paired volumes and radiology reports is a scalable yet challenging task. Existing methods commonly adopt global scan-report contrast, which is scalable but obscures heterogeneous organ evidence. Meanwhile, direct organ-level alignment remains coarse, since the same anatomy can exhibit multiple distinct radiological appearances. Therefore, pretraining requires a finer alignment unit: the organ-conditioned radiological pattern. In this work, we propose OCP-CT, an organ-conditioned pattern-token alignment framework for CT vision-language pretraining. Specifically, OCP-CT preserves a stable global CT-report contrastive branch and introduces an organ pattern interface: sparse Mixture-of-Experts (MoE) routes image and text tokens according to latent radiological patterns, learnable slots query the routed tokens into continuous pattern tokens, and paired token contrast aligns image-text pattern tokens with structured soft targets built from report-derived clinical similarity. On the publicly available CT-RATE and RAD-ChestCT benchmarks, OCP-CT achieves average AUROCs of 84.5% and 69.9% for zero-shot abnormality diagnosis, respectively. Compared with the strongest prior reported results, these results yield absolute AUROC gains of 6.7 and 0.8 percentage points.
Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models. Builds on 23 of its 26 references that are in the map. First posted on arXiv 15 Jul 2026.
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23 of 26 references.
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- 2025Comprehensive language-image pre-training for 3D medical image understanding16 Oct
- 2025Large-scale and Fine-grained Vision-language Pre-training for Enhanced CT Image Understanding24 Jan
- 2024MG-3D: Multi-Grained Knowledge-Enhanced 3D Medical Vision-Language Pre-training8 Dec
- 2024Merlin: A Computed Tomography Vision-Language Foundation Model and Dataset10 Jun
Other references · 19
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- 2021Joint Learning of Localized Representations from Medical Images and Reportscited by 81
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