mlsanityData to 14 Oct 2026

Fine-tuning LLMs for Passive Depression Severity Estimation from AI Mental Health Dialogue

arXiv 2606.17973 ↗First posted 16 Jun 2026cs.CLcited by 2

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Abstract (arXiv)

Depression is the leading cause of disability worldwide, and early detection of symptom change is essential for timely intervention. Validated instruments such as the Patient Health Questionnaire-9 (PHQ-9) support symptom monitoring at scale, but real-world completion rates are low, introducing response bias and systematic missingness. Passive approaches that infer severity from routinely generated data could close this gap. We address this by predicting PHQ-9 total scores directly from transcripts of conversations between users and an AI mental health application, requiring only conversation text and no additional clinical data. We fine-tune a Qwen3.5-27B backbone with a regression head, augment 3,111 ground-truth labels with pseudolabels generated by a reasoning model (Claude Opus) and iteratively trained intermediate models, for a combined dataset of 6,283 users. On a held-out test set of 842 users, our best model achieves MAE = 2.6, RMSE = 4.0, Pearson r = 0.80, and AUC = 0.91 at the PHQ-9 >= 10 clinical threshold. We also find AUC > 0.87 at every severity threshold from PHQ-9 >= 3 to PHQ-9 >= 24, demonstrating that the model captures depression severity across the full clinical spectrum. This work opens the door to passive, continuous symptom monitoring in AI mental health platforms, without requiring users to complete self-report measures.

Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 7 of its 28 references that are in the map. First posted on arXiv 16 Jun 2026.

Builds on

7 of 28 references.

References · 7

  1. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,380
  2. 2019Self-training with Noisy Student improves ImageNet classificationcited by 1,311
  3. 2019Revisiting Self-Training for Neural Sequence Generationcited by 155
  4. 2019AVEC 2019 Workshop and Challenge: State-of-Mind, Detecting Depression with AI, and Cross-Cultural Affect Recognitioncited by 87
  5. 2024DAIC-WOZ: On the Validity of Using the Therapist's prompts in Automatic Depression Detection from Clinical Interviewscited by 15
  6. 2025DIAL: Direct Iterative Adversarial Learning for Realistic Multi-Turn Dialogue Simulationcited by 5
  7. 2025Probabilistic Textual Time Series Depression Detectioncited by 1

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 2.

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  1. 2025Enhancing Depression Detection with Chain-of-Thought Prompting: From Emotion to Reasoning Using Large Language Models
  2. 2023From Classification to Clinical Insights: Towards Analyzing and Reasoning About Mobile and Behavioral Health Data With Large Language Models
  3. 2026Interpretable Symptom Vectors for Depression in a Large Language Model
  4. 2026Dep-LLM: Training-Free Depression Diagnosis via Evidence-Guided Structured Multi-factor with Reliable LLM Reasoning
  5. 2026ADAPTS: Agentic Decomposition for Automated Protocol-agnostic Tracking of Symptoms
  6. 2024InterMind: Doctor-Patient-Family Interactive Depression Assessment Empowered by Large Language Models
  7. 2025DepressLLM: Interpretable domain-adapted language model for depression detection from real-world narratives
  8. 2025Systematic Evaluation of Machine-Generated Reasoning and PHQ-9 Labeling for Depression Detection Using Large Language Models