Attention-Based Prototype Calibration for Multi-Rater Few-Shot Medical Image Segmentation
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Abstract (arXiv)
Few-shot medical image segmentation methods typically assume a single ground-truth annotation, overlooking systematic variability across expert raters commonly observed in clinical datasets. We propose an attention-based prototype calibration framework for few-shot multi-rater segmentation that models rater-specific deviations from a consensus representation in prototype space. A lightweight yet principled attention operator directly refines rater prototypes without modifying the backbone feature extractor, making the approach fully compatible with existing prototype-based few-shot segmentation methods. This design preserves semantic consistency while enabling personalized segmentation outputs with minimal computational overhead. Experiments on multi-rater medical imaging datasets demonstrate consistent improvements over baseline prototype approaches, highlighting the effectiveness of structured prototype calibration for modeling annotation variability.
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References · 16
- 2017Rethinking Atrous Convolution for Semantic Image Segmentationcited by 2,161
- 2019PANet: Few-Shot Image Semantic Segmentation with Prototype Alignmentcited by 449
- 2018A Probabilistic U-Net for Segmentation of Ambiguous Imagescited by 283
- 2022Medical Image Segmentation Review: The success of U-Netcited by 191
- 2019PHiSeg: Capturing Uncertainty in Medical Image Segmentationcited by 128
- 2019'Squeeze & Excite' Guided Few-Shot Segmentation of Volumetric Imagescited by 69
- 2022Anomaly Detection-Inspired Few-Shot Medical Image Segmentation Through Self-Supervision With Supervoxelscited by 42
- 2022Few-shot Medical Image Segmentation with Cycle-resemblance Attentioncited by 33
- 2023Few-Shot Medical Image Segmentation via a Region-enhanced Prototypical Transformercited by 28
- 2022Q-Net: Query-Informed Few-Shot Medical Image Segmentationcited by 24
- 2023Few Shot Medical Image Segmentation with Cross Attention Transformercited by 19
- 2024QUBIQ: Uncertainty Quantification for Biomedical Image Segmentation Challengecited by 13
4 more
- 2021Modeling Annotator Preference and Stochastic Annotation Error for Medical Image Segmentationcited by 12
- 2024Diversified and Personalized Multi-rater Medical Image Segmentationcited by 9
- 2025Concentrate on Weakness: Mining Hard Prototypes for Few-Shot Medical Image Segmentationcited by 3
- 2025Tied Prototype Model for Few-Shot Medical Image Segmentationcited by 1
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