GloResNet: A lightweight 3D CNN with global topological features for preterm brain injury prediction
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Abstract (arXiv)
This study introduces an automated deep learning framework for predicting brain injury (BI) in preterm infants from T2-weighted MRI (dHCP dataset). We propose GloResNet, a lightweight 3D CNN based on ResNet-10, pretrained on MedicalNet to address data scarcity. A global manifold mapping strategy first resamples each 3D volume to 128x128x128 and then applies subject-wise z-score intensity normalization, thereby preserving global topology while standardizing appearance. Training integrates mixup, class weighting, and test-time augmentation for robustness. In 5-fold cross-validation, GloResNet achieved 75.18% average accuracy (peak 81.82%), with specificity 0.81 and sensitivity 0.76. Results demonstrate that a topology-aware lightweight CNN has the capability to effectively predict neonatal BI, offering a non-invasive screening tool. The source code of this paper can be obtained from the GitHub repository: https://github.com/ICL-SUST/GloResNet-Preterm-Brain
Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Builds on 18 of its 116 references that are in the map. First posted on arXiv 1 Jun 2026.
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18 of 116 references.
References · 18
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- 2024Neuron Abandoning Attention Flow: Visual Explanation of Dynamics inside CNN Modelscited by 3
- 2026Second-order Gaussian directional derivative representations for image high-resolution corner detectioncited by 3
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