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VitalAgent: A Tool-Augmented Agent for Reactive and Proactive Physiological Monitoring over Wearable Health Data

arXiv 2605.29483 ↗First posted 28 May 2026cs.AIcited by 0

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Abstract (arXiv)

Wearable devices enable continuous monitoring of physiological signals such as ECG and PPG, but existing mHealth systems are largely limited to task-specific prediction pipelines or reactive question answering over static summaries. They lack the ability to support temporal reasoning, persistent physiological context, and proactive monitoring over long-term signal streams. We propose VitalAgent, a tool-augmented agentic framework for ECG/PPG-based mHealth that supports both reactive question answering and proactive monitoring. VitalAgent is built on a longitudinal physiological memory and a tool-augmented reasoning interface that enables dynamic computation over raw signals. We further introduce VitalBench, a longitudinal physiological monitoring benchmark dataset comprising 1,862 QA pairs for reactive question answering and 90.2 hours of continuous ECG/PPG recordings for proactive monitoring, covering cardiac, physical activity, and stress-related tasks. Experiments demonstrate that VitalAgent achieves over 25% improvement over prompt-based and ReAct baselines in reactive evaluation and supports proactive alert monitoring over long-term physiological signals, highlighting the importance of dynamic tool use and long-term physiological monitoring.

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References · 11

  1. 2022ReAct: Synergizing Reasoning and Acting in Language Modelscited by 8,695
  2. 2022Large Language Models Encode Clinical Knowledgecited by 1,830
  3. 2026DeepSeek-V4: Towards Highly Efficient Million-Token Context Intelligencecited by 1,040
  4. 2024PaPaGei: Open Foundation Models for Optical Physiological Signalscited by 69
  5. 2023ECG-QA: A Comprehensive Question Answering Dataset Combined With Electrocardiogramcited by 54
  6. 2024Toward Foundation Model for Multivariate Wearable Sensing of Physiological Signalscited by 32
  7. 2024An Electrocardiogram Foundation Model Built on over 10 Million Recordings with External Evaluation across Multiple Domainscited by 27
  8. 2025SensorQA: A Question Answering Benchmark for Daily-Life Monitoringcited by 8
  9. 2025ECG-Expert-QA: A Benchmark for Evaluating Medical Large Language Models in Heart Disease Diagnosiscited by 6
  10. 2024Electrocardiogram-Language Model for Few-Shot Question Answering with Meta Learningcited by 5
  11. 2025An LLM-Powered Agent for Physiological Data Analysis: A Case Study on PPG-based Heart Rate Estimationcited by 4

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  1. 2026WearableQA: A Benchmark for Health Reasoning over Real-World Wearable Data
  2. 2026PhysioBench: A Unified Benchmark for Physiological Signal Question Answering
  3. 2026HealthLoopQA: A Context-Aware Question Answering Benchmark for Interpreting Wearable Monitoring Data in Diabetes Care
  4. 2026A Task-Oriented Multi-Agent Framework for Complex Wearable Health Analysis
  5. 2026WEQA: Wearable hEalth Question Answering with Query-Adaptive Agentic Reasoning
  6. 2026VitalDiagnosis: AI-Driven Ecosystem for 24/7 Vital Monitoring and Chronic Disease Management
  7. 2026A Multi-Agent Framework for Interpreting Multivariate Physiological Time Series
  8. 2026SAGE: Sensor-Augmented Grounding Engine for LLM-Powered Sleep Care Agent