mlsanityData to 14 Oct 2026

A Scalable Nonparametric Continuous-Time Survival Model through Numerical Quadrature

arXiv 2605.16208 ↗First posted 15 May 2026stat.ML cs.LGcited by 0

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Abstract (arXiv)

Flexible continuous-time survival modeling is critical for capturing complex time-varying hazard dynamics in high-dimensional data; however, training such models remains challenging due to the intractable integral required for likelihood estimation. We introduce QSurv, a scalable deep learning framework that enables nonparametric continuous-time modeling without relying on time discretization or restrictive distributional assumptions. We propose a training objective based on Gauss-Legendre numerical quadrature, which approximates the cumulative hazard with high-order accuracy while facilitating efficient end-to-end training via standard backpropagation. Furthermore, to effectively capture non-stationary hazard dynamics in complex architectures, we introduce time-conditioned low-rank adaptation, a mechanism that conditions general neural backbones on time by dynamically modulating weights via low-rank updates. We provide theoretical analysis establishing approximation error bounds for cumulative-hazard evaluation. Comprehensive experiments across synthetic benchmarks, large-scale real-world tabular datasets, and high-dimensional medical imaging tasks demonstrate that QSurv achieves competitive predictive performance with advantages in instantaneous hazard function estimation, enabling more interpretable characterization of time-varying risk patterns.

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References · 21

  1. 2017Attention Is All You Needcited by 60,361
  2. 2015Deep Residual Learning for Image Recognitioncited by 52,096
  3. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
  4. 2016Densely Connected Convolutional Networkscited by 6,720
  5. 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 511
  6. 2016DeepSurv: Personalized Treatment Recommender System Using A Cox Proportional Hazards Deep Neural Networkcited by 358
  7. 2019Time2Vec: Learning a Vector Representation of Timecited by 213
  8. 2019Time-to-Event Prediction with Neural Networks and Cox Regressioncited by 175
  9. 2023Deep Learning for Survival Analysis: A Reviewcited by 75
  10. 2018A Scalable Discrete-Time Survival Model for Neural Networkscited by 72
  11. 2020Deep Survival Machines: Fully Parametric Survival Regression and Representation Learning for Censored Data with Competing Riskscited by 70
  12. 2018Effective Ways to Build and Evaluate Individual Survival Distributionscited by 64
9 more
  1. 2016Deep Survival Analysiscited by 61
  2. 2018Deep Neural Networks for Survival Analysis Based on a Multi-Task Frameworkcited by 45
  3. 2021Deep Cox Mixtures for Survival Regressioncited by 44
  4. 2018Countdown Regression: Sharp and Calibrated Survival Predictionscited by 31
  5. 2020SODEN: A Scalable Continuous-Time Survival Model through Ordinary Differential Equation Networkscited by 26
  6. 2021Survival stacking: casting survival analysis as a classification problemcited by 13
  7. 2020Estimation of conditional mixture Weibull distribution with right-censored data using neural network for time-to-event analysiscited by 11
  8. 2022Survival Mixture Density Networkscited by 9
  9. 2020Survival Analysis via Ordinary Differential Equationscited by 6

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