BIT.UA-AAUBS at ArchEHR-QA 2026: Evaluating Open-Source and Proprietary LLMs via Prompting in Low-Resource QA
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Abstract (arXiv)
This paper presents the joint participation of the BIT.UA and AAUBS groups in the ArchEHR-QA 2026 shared task, which focuses on clinical question answering and evidence grounding in a low-resource setting. Due to the absence of training data and the strict data privacy constraints inherent to the healthcare domain (e.g. GDPR), we investigate the capabilities of Large Language Models (LLMs) without weight updates. We evaluate several state-of-the-art proprietary models and locally deployable open-source alternatives using various prompt engineering strategies, including task decomposition, Chain-of-Thought, and in-context learning. Furthermore, we explore majority voting and LLM-as-a-judge ensembling techniques to maximize predictive robustness. Our results demonstrate that while proprietary models exhibit strong resilience to prompt variations, domain-adapted open-source models (such as MedGemma 3 27B) achieve highly competitive performance when paired with the right prompt. Overall, our prompt-based approach proved highly effective, securing 1st place in Subtask 4 (evidence citation alignment) and 3rd place in Subtask 3 (patient-friendly answer generation). All code, results, and prompts are available on our GitHub repository: https://github.com/bioinformatics-ua/ArchEHR-QA-2026.
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References · 11
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- 2024OpenMedLM: Prompt engineering can out-perform fine-tuning in medical question-answering with open-source large language models
- 2025Instruction Tuning and CoT Prompting for Contextual Medical QA with LLMs
- 2026MedPriv-Bench: Benchmarking the Privacy-Utility Trade-off of Large Language Models in Medical Open-Ended Question Answering
- 2025Neural at ArchEHR-QA 2025: Agentic Prompt Optimization for Evidence-Grounded Clinical Question Answering
- 2026Neural at ArchEHR-QA 2026: One Method Fits All: Unified Prompt Optimization for Clinical QA over EHRs
- 2026When Chain-of-Thought Backfires: Evaluating Prompt Sensitivity in Medical Language Models
- 2026Yale-DM-Lab at ArchEHR-QA 2026: Deterministic Grounding and Multi-Pass Evidence Alignment for EHR Question Answering
- 2024Give me Some Hard Questions: Synthetic Data Generation for Clinical QA