Fidelity, Diversity, and Privacy: A Multi-Dimensional LLM Evaluation for Clinical Data Augmentation
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Abstract (arXiv)
The scarcity of high-quality annotated medical data, particularly in mental health, poses a significant bottleneck for training robust machine learning models. Privacy regulations restrict data sharing, making synthetic data generation a promising alternative. The use of Large Language Models (LLMs) in a data augmentation pipeline could be leveraged as an alternative in this field. In the proposed methodology, DeepSeek-R1, OpenBioLLM-Llama3 and Qwen 3.5 are used to generate synthetic mental health evaluation reports conditioned on specific International Classification of Diseases, Tenth Revision (ICD-10) codes. Because naive text generation can lead to mode collapse or privacy breaches (memorization), a comprehensive evaluation framework is introduced. The generated diagnostic texts are assessed across three dimensions: semantic fidelity, lexical diversity, and privacy/plagiarism. The results demonstrate that all models can generate clinically coherent, diverse, and privacy-safe synthetic reports, significantly expanding the available training data for clinical natural language processing tasks without compromising patient confidentiality.
Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Builds on 8 of its 23 references that are in the map. First posted on arXiv 29 Apr 2026.
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8 of 23 references.
References · 8
- 2019BERTScore: Evaluating Text Generation with BERTcited by 5,462
- 2018UMAP: Uniform Manifold Approximation and Projection for Dimension Reductioncited by 2,841
- 2019EDA: Easy Data Augmentation Techniques for Boosting Performance on Text Classification Taskscited by 800
- 2018Texygen: A Benchmarking Platform for Text Generation Modelscited by 484
- 2023AugGPT: Leveraging ChatGPT for Text Data Augmentationcited by 128
- 2019Augmenting Data with Mixup for Sentence Classification: An Empirical Studycited by 125
- 2025Text Data Augmentation for Large Language Models: A Comprehensive Survey of Methods, Challenges, and Opportunitiescited by 21
- 2024A Hybrid Framework with Large Language Models for Rare Disease Phenotypingcited by 7
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Citing papers per year: 2026: 1.
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- 2024Synthetic Data Generation with LLM for Improved Depression Prediction
- 2026Knowledge-Guided Retrieval-Augmented Generation for Zero-Shot Psychiatric Data: Privacy Preserving Synthetic Data Generation
- 2024Zero-shot and Few-shot Generation Strategies for Artificial Clinical Records
- 2025A Scoping Review of Synthetic Data Generation by Language Models in Biomedical Research and Application: Data Utility and Quality Perspectives
- 2024Utilizing Large Language Models to Generate Synthetic Data to Increase the Performance of BERT-Based Neural Networks
- 2023Does Synthetic Data Generation of LLMs Help Clinical Text Mining?