Toward Aristotelian Medical Representations: Backpropagation-Free Layer-wise Analysis for Interpretable Generalized Metric Learning on MedMNIST
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Abstract (arXiv)
While deep learning has achieved remarkable success in medical imaging, the "black-box" nature of backpropagation-based models remains a significant barrier to clinical adoption. To bridge this gap, we propose Aristotelian Rapid Object Modeling (A-ROM), a framework built upon the Platonic Representation Hypothesis (PRH). This hypothesis posits that models trained on vast, diverse datasets converge toward a universal and objective representation of reality. By leveraging the generalizable metric space of pretrained Vision Transformers (ViTs), A-ROM enables the rapid modeling of novel medical concepts without the computational burden or opacity of further gradient-based fine-tuning. We replace traditional, opaque decision layers with a human-readable concept dictionary and a k-Nearest Neighbors (kNN) classifier to ensure the model's logic remains interpretable. Experiments on the MedMNIST v2 suite demonstrate that A-ROM delivers performance competitive with standard benchmarks while providing a simple and scalable, "few-shot" solution that meets the rigorous transparency demands of modern clinical environments.
Key facts. Cited by 2 papers in the map (data through 7 Oct 2026). Builds on 23 of its 37 references that are in the map. First posted on arXiv 7 Apr 2026.
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23 of 37 references.
References · 23
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11 more
- 2024Rethinking model prototyping through the MedMNIST+ dataset collectioncited by 9
- 2025Proof of a perfect platonic representation hypothesiscited by 6
- 2025A Tale of Two Classes: Adapting Supervised Contrastive Learning to Binary Imbalanced Datasetscited by 5
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- 2025Brain-Language Model Alignment: Insights into the Platonic Hypothesis and Intermediate-Layer Advantagecited by 4
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- 2025Optimal Transport Adapter Tuning for Bridging Modality Gaps in Few-Shot Remote Sensing Scene Classificationcited by 1
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Citing papers per year: 2026: 2.
2 papers.