A Safety-Aware Role-Orchestrated Multi-Agent LLM Framework for Behavioral Health Communication Simulation
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Single-agent large language model (LLM) systems struggle to simultaneously support diverse conversational functions and maintain safety in behavioral health communication. We propose a safety-aware, role-orchestrated multi-agent LLM framework designed to simulate supportive behavioral health dialogue through coordinated, role-differentiated agents. Conversational responsibilities are decomposed across specialized agents, including empathy-focused, action-oriented, and supervisory roles, while a prompt-based controller dynamically activates relevant agents and enforces continuous safety auditing. Using semi-structured interview transcripts from the DAIC-WOZ corpus, we evaluate the framework with scalable proxy metrics capturing structural quality, functional diversity, and computational characteristics. Results illustrate clear role differentiation, coherent inter-agent coordination, and predictable trade-offs between modular orchestration, safety oversight, and response latency when compared to a single-agent baseline. This work emphasizes system design, interpretability, and safety, positioning the framework as a simulation and analysis tool for behavioral health informatics and decision-support research rather than a clinical intervention.
Key facts. Cited by 1 paper in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 12 of its 22 references that are in the map. First posted on arXiv 31 Mar 2026.
Builds on
12 of 22 references.
Closest ancestors · 2
Same direction, newest first
- 2024Script-Based Dialog Policy Planning for LLM-Powered Conversational Agents: A Basic Architecture for an "AI Therapist"13 Dec
- 2024Beyond Direct Diagnosis: LLM-based Multi-Specialist Agent Consultation for Automatic Diagnosis29 Jan
Other references · 10
- 2023Generative Agents: Interactive Simulacra of Human Behaviorcited by 3,500
- 2023AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversationcited by 1,906
- 2021Prompt Programming for Large Language Models: Beyond the Few-Shot Paradigmcited by 599
- 2023MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoningcited by 311
- 2023Towards Interpretable Mental Health Analysis with Large Language Modelscited by 53
- 2024Optima: Optimizing Effectiveness and Efficiency for LLM-Based Multi-Agent Systemcited by 40
- 2018Utilizing Neural Networks and Linguistic Metadata for Early Detection of Depression Indications in Text Sequencescited by 36
- 2025OSC: Cognitive Orchestration through Dynamic Knowledge Alignment in Multi-Agent LLM Collaborationcited by 29
- 2025EmoAgent: Assessing and Safeguarding Human-AI Interaction for Mental Health Safetycited by 21
- 2024Turn-Level Empathy Prediction Using Psychological Indicatorscited by 1
Built on by
Citing papers per year: 2026: 1.
1 paper.
- 2026Can LLM Agents Sustain Long-Horizon Organizational Dynamics?31 May 2026
Similar, not cited
Close in wording, no citation either way
- 2025MATRIX: Multi-Agent simulaTion fRamework for safe Interactions and conteXtual clinical conversational evaluation
- 2025DialogGuard: Multi-Agent Psychosocial Safety Evaluation of Sensitive LLM Responses
- 2025Tiered Agentic Oversight: A Hierarchical Multi-Agent System for Healthcare Safety
- 2025Beyond Reactive Safety: Risk-Aware LLM Alignment via Long-Horizon Simulation
- 2026"Who Am I, and Who Else Is Here?" Behavioral Differentiation Without Role Assignment in Multi-Agent LLM Systems
- 2024Building Trust in Mental Health Chatbots: Safety Metrics and LLM-Based Evaluation Tools
- 2026SafeTalkCoach: Diversity-Driven Multi-Agent Simulation for Parent-Teen Health Conversations
- 2026The Supportiveness-Safety Tradeoff in LLM Well-Being Agents