Separating Diagnosis from Control: Auditable Policy Adaptation in Agent-Based Simulations with LLM-Based Diagnostics
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Mitigating elderly loneliness requires policy interventions that achieve both adaptability and auditability. Existing methods struggle to reconcile these objectives: traditional agent-based models suffer from static rigidity, while direct large language model (LLM) controllers lack essential traceability. This work proposes a three-layer framework that separates diagnosis from control to achieve both properties simultaneously. LLMs operate strictly as diagnostic instruments that assess population state and generate structured risk evaluations, while deterministic formulas with explicit bounds translate these assessments into traceable parameter updates. This separation ensures that every policy decision can be attributed to inspectable rules while maintaining adaptive response to emergent needs. We validate the framework through systematic ablation across five experimental conditions in elderly care simulation. Results demonstrate that explicit control rules outperform end-to-end black-box LLM approaches by 11.7% while preserving full auditability, confirming that transparency need not compromise adaptive performance.
Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 9 of its 22 references that are in the map. First posted on arXiv 24 Mar 2026.
Builds on
9 of 22 references.
References · 9
- 2023Generative Agents: Interactive Simulacra of Human Behaviorcited by 3,568
- 2023Large Language Models Empowered Agent-based Modeling and Simulation: A Survey and Perspectivescited by 257
- 2020Explainability in Deep Reinforcement Learningcited by 97
- 2024Promptable Closed-loop Traffic Simulationcited by 20
- 2024Surrogate Modeling and Control of Medical Digital Twinscited by 8
- 2024Casevo: A Cognitive Agents and Social Evolution Simulatorcited by 8
- 2025G-Sim: Generative Simulations with Large Language Models and Gradient-Free Calibrationcited by 8
- 2025Simulation Agent: A Framework for Integrating Simulation and Large Language Models for Enhanced Decision-Makingcited by 4
- 2026Coordinated Pandemic Control with Large Language Model Agents as Policymaking Assistantscited by 3
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Citing papers per year: 2026: 1.
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- 2026AD-CARE: A Guideline-grounded, Modality-agnostic LLM Agent for Real-world Alzheimer's Disease Diagnosis with Multi-cohort Assessment, Fairness Analysis, and Reader Study
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