Multi-head automated segmentation by incorporating detection head into the contextual layer neural network
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Abstract (arXiv)
Deep learning based auto segmentation is increasingly used in radiotherapy, but conventional models often produce anatomically implausible false positives, or hallucinations, in slices lacking target structures. We propose a gated multi-head Transformer architecture based on Swin U-Net, augmented with inter-slice context integration and a parallel detection head, which jointly performs slice-level structure detection via a multi-layer perceptron and pixel-level segmentation through a context-enhanced stream. Detection outputs gate the segmentation predictions to suppress false positives in anatomically invalid slices, and training uses slice-wise Tversky loss to address class imbalance. Experiments on the Prostate-Anatomical-Edge-Cases dataset from The Cancer Imaging Archive demonstrate that the gated model substantially outperforms a non-gated segmentation-only baseline, achieving a mean Dice loss of 0.013 ± 0.036 versus 0.732 ± 0.314, with detection probabilities strongly correlated with anatomical presence, effectively eliminating spurious segmentations. In contrast, the non-gated model exhibited higher variability and persistent false positives across all slices. These results indicate that detection-based gating enhances robustness and anatomical plausibility in automated segmentation applications, reducing hallucinated predictions without compromising segmentation quality in valid slices, and offers a promising approach for improving the reliability of clinical radiotherapy auto-contouring workflows.
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References · 8
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2020Annotation-efficient deep learning for automatic medical image segmentationcited by 79
- 2018AnatomyNet: Deep Learning for Fast and Fully Automated Whole-volume Segmentation of Head and Neck Anatomycited by 54
- 2023Loss Functions and Metrics in Deep Learningcited by 42
- 2024Sli2Vol+: Segmenting 3D Medical Images Based on an Object Estimation Guided Correspondence Flow Networkcited by 5
- 2018UOLO - automatic object detection and segmentation in biomedical imagescited by 4
- 2023HALOS: Hallucination-free Organ Segmentation after Organ Resection Surgerycited by 3
- 2024Deep-learning Segmentation of Small Volumes in CT images for Radiotherapy Treatment Planningcited by 1
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