On The Robustness of Foundational 3D Medical Image Segmentation Models Against Imprecise Visual Prompts
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Abstract (arXiv)
While 3D foundational models have shown promise for promptable segmentation of medical volumes, their robustness to imprecise prompts remains under-explored. In this work, we aim to address this gap by systematically studying the effect of various controlled perturbations of dense visual prompts, that closely mimic real-world imprecision. By conducting experiments with two recent foundational models on a multi-organ abdominal segmentation task, we reveal several facets of promptable medical segmentation, especially pertaining to reliance on visual shape and spatial cues, and the extent of resilience of models towards certain perturbations. Codes are available at: https://github.com/ucsdbiag/Prompt-Robustness-MedSegFMs
Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 10 of its 18 references that are in the map. First posted on arXiv 23 Jan 2026.
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10 of 18 references.
References · 10
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- 2023Segment Anythingcited by 8,234
- 2023Segment Anything in Medical Imagescited by 227
- 2023SAM-Med2Dcited by 124
- 2023SegVol: Universal and Interactive Volumetric Medical Image Segmentationcited by 87
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- 2024uniGradICON: A Foundation Model for Medical Image Registrationcited by 58
- 2025nnInteractive: Redefining 3D Promptable Segmentationcited by 41
- 2024multiGradICON: A Foundation Model for Multimodal Medical Image Registrationcited by 16
- 2025Zero-shot Domain Generalization of Foundational Models for 3D Medical Image Segmentation: An Experimental Studycited by 3
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Citing papers per year: 2026: 2.
2 papers.