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Deep Learning-Based Computer Vision Models for Early Cancer Detection Using Multimodal Medical Imaging and Radiogenomic Integration Frameworks

arXiv 2512.00714 ↗First posted 30 Nov 2025cs.CV cs.AIcited by 0

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Abstract (arXiv)

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have enabled transformative progress in medical imaging analysis. Deep learning-based computer vision models, such as convolutional neural networks (CNNs), transformers, and hybrid attention architectures, can automatically extract complex spatial, morphological, and temporal patterns from multimodal imaging data including MRI, CT, PET, mammography, histopathology, and ultrasound. These models surpass traditional radiological assessment by identifying subtle tissue abnormalities and tumor microenvironment variations invisible to the human eye. At a broader scale, the integration of multimodal imaging with radiogenomics linking quantitative imaging features with genomics, transcriptomics, and epigenetic biomarkers has introduced a new paradigm for personalized oncology. This radiogenomic fusion allows the prediction of tumor genotype, immune response, molecular subtypes, and treatment resistance without invasive biopsies.

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References · 4

  1. 2021Deep Orthogonal Fusion: Multimodal Prognostic Biomarker Discovery Integrating Radiology, Pathology, Genomic, and Clinical Datacited by 29
  2. 2023Multimodal Data Integration for Oncology in the Era of Deep Neural Networks: A Reviewcited by 20
  3. 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
  4. 2025From Classical Machine Learning to Emerging Foundation Models: Review on Multimodal Data Integration for Cancer Researchcited by 6

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