Evaluating Prompting Strategies and Large Language Models in Systematic Literature Review Screening: Relevance and Task-Stage Classification
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Abstract (arXiv)
This study quantifies how prompting strategies interact with large language models (LLMs) to automate the screening stage of systematic literature reviews (SLRs). We evaluate six LLMs (GPT-4o, GPT-4o-mini, DeepSeek-Chat-V3, Gemini-2.5-Flash, Claude-3.5-Haiku, Llama-4-Maverick) under five prompt types (zero-shot, few-shot, chain-of-thought (CoT), CoT-few-shot, self-reflection) across relevance classification and six Level-2 tasks, using accuracy, precision, recall, and F1. Results show pronounced model-prompt interaction effects: CoT-few-shot yields the most reliable precision-recall balance; zero-shot maximizes recall for high-sensitivity passes; and self-reflection underperforms due to over-inclusivity and instability across models. GPT-4o and DeepSeek provide robust overall performance, while GPT-4o-mini performs competitively at a substantially lower dollar cost. A cost-performance analysis for relevance classification (per 1,000 abstracts) reveals large absolute differences among model-prompt pairings; GPT-4o-mini remains low-cost across prompts, and structured prompts (CoT/CoT-few-shot) on GPT-4o-mini offer attractive F1 at a small incremental cost. We recommend a staged workflow that (1) deploys low-cost models with structured prompts for first-pass screening and (2) escalates only borderline cases to higher-capacity models. These findings highlight LLMs' uneven but promising potential to automate literature screening. By systematically analyzing prompt-model interactions, we provide a comparative benchmark and practical guidance for task-adaptive LLM deployment.
Key facts. Cited by 3 papers in the map (data through 14 Oct 2026). Builds on 18 of its 54 references that are in the map. First posted on arXiv 17 Oct 2025.
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18 of 54 references.
References · 18
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- 2021Prompt Programming for Large Language Models: Beyond the Few-Shot Paradigmcited by 606
- 2023Can large language models replace humans in the systematic review process? Evaluating GPT-4's efficacy in screening and extracting data from peer-reviewed and grey literature in multiple languagescited by 36
- 2020Open Source Software for Efficient and Transparent Reviewscited by 35
6 more
- 2024Automating Research Synthesis with Domain-Specific Large Language Model Fine-Tuningcited by 31
- 2023Automated Paper Screening for Clinical Reviews Using Large Language Modelscited by 29
- 2023Meta Prompting for AI Systemscited by 16
- 2024High-performance automated abstract screening with large language model ensemblescited by 8
- 2024Automated Literature Review Using NLP Techniques and LLM-Based Retrieval-Augmented Generationcited by 8
- 2025Compiling Prompts, Not Crafting Them: A Reproducible Workflow for AI-Assisted Evidence Synthesiscited by 2
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Citing papers per year: 2026: 3.
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- 2025Deep Research: A Systematic Survey
- 2023An Empirical Evaluation of Prompting Strategies for Large Language Models in Zero-Shot Clinical Natural Language Processing
- 2026Why Prompt Optimization Works, and Why It Sometimes Doesn't: A Causal-Inspired Edit-Level Analysis
- 2026Large language models for post-publication research evaluation: Evidence from expert recommendations and citation indicators