Repurposing Annotation Guidelines to Instruct LLM Annotators: A Case Study

This study investigates how existing annotation guidelines can be repurposed to instruct large language model (LLM) annotators for text annotation tasks. Traditional guidelines are written for human annotators who internalize training, while LLMs require explicit, structured instructions. We propose a moderation-oriented guideline repurposing method that transforms guidelines into clear directives for LLMs through an LLM moderation process. Using the NCBI Disease Corpus as a case study, our experiments show that repurposed guidelines can effectively guide LLM annotators, while revealing several practical challenges. The results highlight the potential of this workflow to support scalable and cost-effective refinement of annotation guidelines and automated annotation.