mlsanityData to 14 Oct 2026

Denoising of Two-Phase Optically Sectioned Structured Illumination Reconstructions Using Encoder-Decoder Networks

arXiv 2510.03452 ↗First posted 3 Oct 2025cs.CVcited by 0

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Abstract (arXiv)

Structured illumination (SI) enhances image resolution and contrast by projecting patterned light onto a sample. In two-phase optical-sectioning SI (OS-SI), reduced acquisition time introduces residual artifacts that conventional denoising struggles to suppress. Deep learning offers an alternative to traditional methods; however, supervised training is limited by the lack of clean, optically sectioned ground-truth data. We investigate encoder-decoder networks for artifact reduction in two-phase OS-SI, using synthetic training pairs formed by applying real artifact fields to synthetic images. An asymmetrical denoising autoencoder (DAE) and a U-Net are trained on the synthetic data, then evaluated on real OS-SI images. Both networks improve image clarity, with each excelling against different artifact types. These results demonstrate that synthetic training enables supervised denoising of OS-SI images and highlight the potential of encoder-decoder networks to streamline reconstruction workflows.

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References · 6

  1. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
  2. 2015Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shiftcited by 7,005
  3. 2016Beyond a Gaussian Denoiser: Residual Learning of Deep CNN for Image Denoisingcited by 1,358
  4. 2018Noise2Noise: Learning Image Restoration without Clean Datacited by 533
  5. 2017FFDNet: Toward a Fast and Flexible Solution for CNN based Image Denoisingcited by 510
  6. 2018Noise2Void - Learning Denoising from Single Noisy Imagescited by 364

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