MedGR2: Breaking the Data Barrier for Medical Reasoning via Generative Reward Learning
On the map: LLM reasoning → Clinical and biomedical applications
also in 2 more
Abstract (arXiv)
The application of Vision-Language Models (VLMs) in medicine is critically hampered by the scarcity of high-quality, expert-annotated data. Supervised Fine-Tuning (SFT) on existing datasets often leads to poor generalization on unseen modalities and tasks, while Reinforcement Learning (RL), a promising alternative, is stymied by the lack of reliable reward signals in this data-scarce domain. To break this impasse, we introduce Generative Reward Learning for Medical Reasoning (MedGR2), a novel framework that creates a self-improving virtuous cycle. MedGR2 co-develops a data generator and a reward model, enabling the automated, continuous creation of high-quality, multi-modal medical data that serves as both a superior training source for SFT and RL. Our experiments demonstrate that SFT with MedGR2-produced data already surpasses baselines trained on large-scale, human-curated datasets. Crucially, when leveraging this data for RL via Group Relative Policy Optimization (GRPO), our model achieves state-of-the-art cross-modality and cross-task generalization, significantly outperforming specialized RL-based methods. Furthermore, our compact model, empowered by MedGR2, achieves performance competitive with foundation models possessing over 10 times more parameters. MedGR2 presents a new paradigm for data-efficient learning in high-stakes domains, transforming the problem from data scarcity to data generation and unlocking the full potential of RL for building truly generalizable medical AI.
Key facts. Cited by 8 papers in the map (data through 7 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 14 of its 30 references that are in the map. First posted on arXiv 28 Aug 2025.
Builds on
14 of 30 references.
Closest ancestors · 2
Same direction, newest first
- 2025Med-R1: Reinforcement Learning for Generalizable Medical Reasoning in Vision-Language Models18 Mar
- 2025MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via Reinforcement Learning26 Feb
Other references · 12
- 2025Qwen2.5-VL Technical Reportcited by 5,418
- 2024Qwen2-VL: Enhancing Vision-Language Model's Perception of the World at Any Resolutioncited by 4,151
- 2023MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Modelscited by 2,689
- 2024LLaVA-OneVision: Easy Visual Task Transfercited by 2,669
- 2025SFT Memorizes, RL Generalizes: A Comparative Study of Foundation Model Post-trainingcited by 655
- 2023LLaMA-Adapter V2: Parameter-Efficient Visual Instruction Modelcited by 602
- 2025LIMO: Less is More for Reasoningcited by 488
- 2023PMC-VQA: Visual Instruction Tuning for Medical Visual Question Answeringcited by 333
- 2025Reinforcement Learning for Reasoning in Large Language Models with One Training Examplecited by 288
- 2023Towards Generalist Foundation Model for Radiology by Leveraging Web-scale 2D&3D Medical Datacited by 176
- 2025LIMR: Less is More for RL Scalingcited by 136
- 2025HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptationcited by 112
Built on by
Citing papers per year: 2025: 2; 2026: 6.
8 papers.
- 2025A Survey of Reinforcement Learning for Large Reasoning Modelscited by 175
- 2025Beyond Classification Accuracy: Neural-MedBench and the Need for Deeper Reasoning Benchmarkscited by 3
- 2026Regulating Anatomy-Aware Rewards via Trajectory-Integral Feedback for Volumetric Computed Tomography Analysiscited by 2
- 2026Agri-R1: Agricultural Reasoning for Disease Diagnosis via Automated-Synthesis and Reinforcement Learningcited by 1
- 2026Entropy-KL Divergence-based Token Masking: A Novel Approach for Selective Fine-tuning of Large Language Modelscited by 1
- 2026Breaking Failure Cascades: Step-Aware Reinforcement Learning for Medical Multimodal Reasoningcited by 1
- 2026Med-Evo: Test-time Self-evolution for Medical Multimodal Large Language Modelscited by 0
- 2026Evo-PI: Aligning Medical Reasoning via Evolving Principle-Guided Supervisioncited by 0
- 2026Breaking Failure Cascades: Step-Aware Reinforcement Learning for Medical Multimodal Reasoning30 Jun 2026
- 2026Evo-PI: Aligning Medical Reasoning via Evolving Principle-Guided Supervision30 Jun 2026
- 2026Entropy-KL Divergence-based Token Masking: A Novel Approach for Selective Fine-tuning of Large Language Models28 May 2026
- 2026Regulating Anatomy-Aware Rewards via Trajectory-Integral Feedback for Volumetric Computed Tomography Analysis19 May 2026
- 2026Med-Evo: Test-time Self-evolution for Medical Multimodal Large Language Models8 Mar 2026
- 2026Agri-R1: Agricultural Reasoning for Disease Diagnosis via Automated-Synthesis and Reinforcement Learning8 Jan 2026
- 2025Beyond Classification Accuracy: Neural-MedBench and the Need for Deeper Reasoning Benchmarks26 Sep 2025
- 2025A Survey of Reinforcement Learning for Large Reasoning Models10 Sep 2025
Similar, not cited
Close in wording, no citation either way
- 2025Adaptive Reinforcement for Open-ended Medical Reasoning via Semantic-Guided Reward Collapse Mitigation
- 2026Eliciting Medical Reasoning with Knowledge-enhanced Data Synthesis: A Semi-Supervised Reinforcement Learning Approach
- 2026MediX-R1: Open Ended Medical Reinforcement Learning
- 2025MedGRPO: Multi-Task Reinforcement Learning for Heterogeneous Medical Video Understanding
- 2025Med-RLVR: Emerging Medical Reasoning from a 3B base model via reinforcement Learning
- 2025Fleming-R1: Toward Expert-Level Medical Reasoning via Reinforcement Learning
- 2025Toward Effective Reinforcement Learning Fine-Tuning for Medical VQA in Vision-Language Models
- 2025MedVLThinker: Simple Baselines for Multimodal Medical Reasoning