An Audit and Analysis of LLM-Assisted Health Misinformation Jailbreaks Against LLMs
On the map: LLM safety and security → Safety alignment, refusal and guardrails
Abstract (arXiv)
Large Language Models (LLMs) are a double-edged sword capable of generating harmful misinformation -- inadvertently, or when prompted by "jailbreak" attacks that attempt to produce malicious outputs. LLMs could, with additional research, be used to detect and prevent the spread of misinformation. In this paper, we investigate the efficacy and characteristics of LLM-produced jailbreak attacks that cause other models to produce harmful medical misinformation. We also study how misinformation generated by jailbroken LLMs compares to typical misinformation found on social media, and how effectively it can be detected using standard machine learning approaches. Specifically, we closely examine 109 distinct attacks against three target LLMs and compare the attack prompts to in-the-wild health-related LLM queries. We also examine the resulting jailbreak responses, comparing the generated misinformation to health-related misinformation on Reddit. Our findings add more evidence that LLMs can be effectively used to detect misinformation from both other LLMs and from people, and support a body of work suggesting that with careful design, LLMs can contribute to a healthier overall information ecosystem.
Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Placed in Safety alignment, refusal and guardrails, one of 12 directions in LLM safety and security. Builds on 13 of its 41 references that are in the map. First posted on arXiv 6 Aug 2025.
Builds on
13 of 41 references.
Closest ancestors · 1
Same direction, newest first
- 2025Towards Safe AI Clinicians: A Comprehensive Study on Large Language Model Jailbreaking in Healthcare27 Jan
Other references · 12
- 2021Ethical and social risks of harm from Language Modelscited by 966
- 2024WildChat: 1M ChatGPT Interaction Logs in the Wildcited by 629
- 2024How Johnny Can Persuade LLMs to Jailbreak Them: Rethinking Persuasion to Challenge AI Safety by Humanizing LLMscited by 573
- 2024From Generation to Judgment: Opportunities and Challenges of LLM-as-a-judgecited by 494
- 2023How Close is ChatGPT to Human Experts? Comparison Corpus, Evaluation, and Detectioncited by 481
- 2023Can LLM-Generated Misinformation Be Detected?cited by 177
- 2023Factuality Challenges in the Era of Large Language Modelscited by 126
- 2019r/Fakeddit: A New Multimodal Benchmark Dataset for Fine-grained Fake News Detectioncited by 55
- 2023Tricking LLMs into Disobedience: Formalizing, Analyzing, and Detecting Jailbreakscited by 49
- 2024Exploring the Deceptive Power of LLM-Generated Fake News: A Study of Real-World Detection Challengescited by 30
- 2024What Features in Prompts Jailbreak LLMs? Investigating the Mechanisms Behind Attackscited by 29
- 2024Hidden You Malicious Goal Into Benign Narratives: Jailbreak Large Language Models through Logic Chain Injectioncited by 9
Built on by
Citing papers per year: 2026: 1.
1 paper.
Similar, not cited
Close in wording, no citation either way
- 2024Characterizing and Evaluating the Reliability of LLMs against Jailbreak Attacks
- 2024Securing Large Language Models: Addressing Bias, Misinformation, and Prompt Attacks
- 2025LLMs are Vulnerable to Malicious Prompts Disguised as Scientific Language
- 2025Unmasking Digital Falsehoods: A Comparative Analysis of LLM-Based Misinformation Detection Strategies
- 2025A Survey on Responsible LLMs: Inherent Risk, Malicious Use, and Mitigation Strategy
- 2026JailNewsBench: Multi-Lingual and Regional Benchmark for Fake News Generation under Jailbreak Attacks
- 2025Guardians and Offenders: A Survey on Harmful Content Generation and Safety Mitigation of LLM
- 2024Wait, but Tylenol is Acetaminophen... Investigating and Improving Language Models' Ability to Resist Requests for Misinformation