MultiMedEdit: A Scenario-Aware Benchmark for Evaluating Knowledge Editing in Medical VQA
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Abstract (arXiv)
Knowledge editing (KE) provides a scalable approach for updating factual knowledge in large language models without full retraining. While previous studies have demonstrated effectiveness in general domains and medical QA tasks, little attention has been paid to KE in multimodal medical scenarios. Unlike text-only settings, medical KE demands integrating updated knowledge with visual reasoning to support safe and interpretable clinical decisions. To address this gap, we propose MultiMedEdit, the first benchmark tailored to evaluating KE in clinical multimodal tasks. Our framework spans both understanding and reasoning task types, defines a three-dimensional metric suite (reliability, generality, and locality), and supports cross-paradigm comparisons across general and domain-specific models. We conduct extensive experiments under single-editing and lifelong-editing settings. Results suggest that current methods struggle with generalization and long-tail reasoning, particularly in complex clinical workflows. We further present an efficiency analysis (e.g., edit latency, memory footprint), revealing practical trade-offs in real-world deployment across KE paradigms. Overall, MultiMedEdit not only reveals the limitations of current approaches but also provides a solid foundation for developing clinically robust knowledge editing techniques in the future.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 29 of its 43 references that are in the map. First posted on arXiv 9 Aug 2025.
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References · 29
- 2022Locating and Editing Factual Associations in GPTcited by 2,691
- 2015VQA: Visual Question Answeringcited by 2,506
- 2023LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Daycited by 1,305
- 2022Mass-Editing Memory in a Transformercited by 1,001
- 2022PaLI: A Jointly-Scaled Multilingual Language-Image Modelcited by 766
- 2023The Dawn of LMMs: Preliminary Explorations with GPT-4V(ision)cited by 681
- 2023An Empirical Study of Catastrophic Forgetting in Large Language Models During Continual Fine-tuningcited by 639
- 2021Fast Model Editing at Scalecited by 498
- 2022Memory-Based Model Editing at Scalecited by 447
- 2023Med-Flamingo: a Multimodal Medical Few-shot Learnercited by 392
- 2023Editing Large Language Models: Problems, Methods, and Opportunitiescited by 372
- 2023Can We Edit Factual Knowledge by In-Context Learning?cited by 285
17 more
- 2022Aging with GRACE: Lifelong Model Editing with Discrete Key-Value Adaptorscited by 271
- 2024AlphaEdit: Null-Space Constrained Knowledge Editing for Language Modelscited by 236
- 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 224
- 2024HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scalecited by 200
- 2024OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLMcited by 184
- 2024Revisiting Catastrophic Forgetting in Large Language Model Tuningcited by 99
- 2025Medical Hallucinations in Foundation Models and Their Impact on Healthcarecited by 93
- 2024Learning to Edit: Aligning LLMs with Knowledge Editingcited by 43
- 2024Lifelong Knowledge Editing for LLMs with Retrieval-Augmented Continuous Prompt Learningcited by 40
- 2025MedFrameQA: A Multi-Image Medical VQA Benchmark for Clinical Reasoningcited by 34
- 2024MediConfusion: Can you trust your AI radiologist? Probing the reliability of multimodal medical foundation modelscited by 23
- 2024Retrieval-enhanced Knowledge Editing in Language Models for Multi-Hop Question Answeringcited by 20
- 2024Worse than Random? An Embarrassingly Simple Probing Evaluation of Large Multimodal Models in Medical VQAcited by 19
- 2025CaKE: Circuit-aware Editing Enables Generalizable Knowledge Learnerscited by 9
- 2024O-Edit: Orthogonal Subspace Editing for Language Model Sequential Editingcited by 8
- 2025Tracing and Reversing Edits in LLMscited by 7
- 2025MindBridge: Scalable and Cross-Model Knowledge Editing via Memory-Augmented Modalitycited by 6
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- 2025Beyond Memorization: A Rigorous Evaluation Framework for Medical Knowledge Editing
- 2025MedMKEB: A Comprehensive Knowledge Editing Benchmark for Medical Multimodal Large Language Models
- 2024ComprehendEdit: A Comprehensive Dataset and Evaluation Framework for Multimodal Knowledge Editing
- 2025Elicit and Enhance: Advancing Multimodal Reasoning in Medical Scenarios
- 2026CURE: A Multimodal Benchmark for Clinical Understanding and Retrieval Evaluation
- 2025OctoMed: Data Recipes for State-of-the-Art Multimodal Medical Reasoning
- 2025Medical Reasoning in the Era of LLMs: A Systematic Review of Enhancement Techniques and Applications
- 2025Med-CMR: A Fine-Grained Benchmark Integrating Visual Evidence and Clinical Logic for Medical Complex Multimodal Reasoning