Quantifying surprise in clinical care: Detecting highly informative events in electronic health records with foundation models
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Abstract (arXiv)
We present a foundation model-derived method to identify highly informative tokens and events in electronic health records. Our approach considers incoming data in the entire context of a patient's hospitalization and so can flag anomalous events that rule-based approaches would consider within a normal range. We demonstrate that the events our model flags are significant for predicting downstream patient outcomes and that a fraction of events identified as carrying little information can safely be dropped. Additionally, we show how informativeness can help interpret the predictions of prognostic models trained on foundation model-derived representations.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 25 of its 65 references that are in the map. First posted on arXiv 30 Jul 2025.
Builds on
25 of 65 references.
References · 25
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13 more
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Citing papers per year: 2026: 3.
3 papers.
- 2026Efficient Generative Prediction for EHR Foundation Models: The SCOPE and REACH Estimatorscited by 2
- 2026Representation Before Training: A Practical Benchmark for Generative Medical Event Model Tokenizationcited by 0
- 2026Federated generative event models for tokenized electronic health recordscited by 0
- 2026Federated generative event models for tokenized electronic health records3 Aug 2026
- 2026Representation Before Training: A Practical Benchmark for Generative Medical Event Model Tokenization18 Apr 2026
- 2026Efficient Generative Prediction for EHR Foundation Models: The SCOPE and REACH Estimators3 Feb 2026