Adverse Event Extraction from Discharge Summaries: A New Dataset, Annotation Scheme, and Initial Findings
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Abstract (arXiv)
In this work, we present a manually annotated corpus for Adverse Event (AE) extraction from discharge summaries of elderly patients, a population often underrepresented in clinical NLP resources. The dataset includes 14 clinically significant AEs-such as falls, delirium, and intracranial haemorrhage, along with contextual attributes like negation, diagnosis type, and in-hospital occurrence. Uniquely, the annotation schema supports both discontinuous and overlapping entities, addressing challenges rarely tackled in prior work. We evaluate multiple models using FlairNLP across three annotation granularities: fine-grained, coarse-grained, and coarse-grained with negation. While transformer-based models (e.g., BERT-cased) achieve strong performance on document-level coarse-grained extraction (F1 = 0.943), performance drops notably for fine-grained entity-level tasks (e.g., F1 = 0.675), particularly for rare events and complex attributes. These results demonstrate that despite high-level scores, significant challenges remain in detecting underrepresented AEs and capturing nuanced clinical language. Developed within a Trusted Research Environment (TRE), the dataset is available upon request via DataLoch and serves as a robust benchmark for evaluating AE extraction methods and supporting future cross-dataset generalisation.
Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 4 of its 68 references that are in the map. First posted on arXiv 17 Jun 2025.
Builds on
4 of 68 references.
References · 4
- 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,399
- 2020An Effective Transition-based Model for Discontinuous NERcited by 33
- 2021Extracting Adverse Drug Events from Clinical Notescited by 7
- 2024MultiADE: A Multi-domain Benchmark for Adverse Drug Event Extractioncited by 1
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Citing papers per year: 2025: 1; 2026: 1.
2 papers.
- 2026Applicability Condition Extraction for Therapeutic Drug-Disease Relations12 Jun 2026
- 2025Event Extraction in Large Language Model22 Dec 2025