mlsanityData to 14 Oct 2026

Research on Personalized Medical Intervention Strategy Generation System based on Group Relative Policy Optimization and Time-Series Data Fusion

arXiv 2504.18631 ↗First posted 25 Apr 2025cs.AI cs.LGcited by 6

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Abstract (arXiv)

With the timely formation of personalized intervention plans based on high-dimensional heterogeneous time series information becoming an important challenge in the medical field today, electronic medical records, wearables, and other multi-source medical data are increasingly generated and diversified. In this work, we develop a system to generate personalized medical intervention strategies based on Group Relative Policy Optimization (GRPO) and Time-Series Data Fusion. First, by incorporating relative policy constraints among the groups during policy gradient updates, we adaptively balance individual and group gains. To improve the robustness and interpretability of decision-making, a multi-layer neural network structure is employed to group-code patient characteristics. Second, for the rapid multi-modal fusion of multi-source heterogeneous time series, a multi-channel neural network combined with a self-attention mechanism is used for dynamic feature extraction. Key feature screening and aggregation are achieved through a differentiable gating network. Finally, a collaborative search process combining a genetic algorithm and Monte Carlo tree search is proposed to find the ideal intervention strategy, achieving global optimization. Experimental results show significant improvements in accuracy, coverage, and decision-making benefits compared with existing methods.

Key facts. Cited by 6 papers in the map (data through 14 Oct 2026). Builds on 3 of its 22 references that are in the map. First posted on arXiv 25 Apr 2025.

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3 of 22 references.

References · 3

  1. 2025Unmasking Digital Falsehoods: A Comparative Analysis of LLM-Based Misinformation Detection Strategiescited by 16
  2. 2023Deep Learning based Multi-Label Image Classification of Protest Activitiescited by 14
  3. 2025Psychological Health Knowledge-Enhanced LLM-based Social Network Crisis Intervention Text Transfer Recognition Methodcited by 7

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Citing papers per year: 2025: 6.

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  1. 2024Dynamic feature selection in medical predictive monitoring by reinforcement learning
  2. 2018A clustering-based reinforcement learning approach for tailored personalization of e-Health interventions
  3. 2025Personalized Treatment Outcome Prediction from Scarce Data via Dual-Channel Knowledge Distillation and Adaptive Fusion
  4. 2025EQPO: Equitable Group Relative Policy Optimization for Clinical Reasoning
  5. 2026Improving Heart-Focused Medical Question Answering in LLMs via Variance-Aware Rubric Rewards with GRPO
  6. 2025MIRA: Medical Time Series Foundation Model for Real-World Health Data
  7. 2026A Unified Benchmark for Dynamic Medical Treatment Reinforcement Learning
  8. 2024Medical Knowledge Integration into Reinforcement Learning Algorithms for Dynamic Treatment Regimes