Precise Insulin Delivery for Artificial Pancreas: A Reinforcement Learning Optimized Adaptive Fuzzy Control Approach
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Abstract (arXiv)
This paper explores the application of reinforcement learning to optimize the parameters of a Type-1 Takagi-Sugeno fuzzy controller, designed to operate as an artificial pancreas for Type 1 diabetes. The primary challenge in diabetes management is the dynamic nature of blood glucose levels, which are influenced by several factors such as meal intake and timing. Traditional controllers often struggle to adapt to these changes, leading to suboptimal insulin administration. To address this issue, we employ a reinforcement learning agent tasked with adjusting 27 parameters of the Takagi-Sugeno fuzzy controller at each time step, ensuring real-time adaptability. The study's findings demonstrate that this approach significantly enhances the robustness of the controller against variations in meal size and timing, while also stabilizing glucose levels with minimal exogenous insulin. This adaptive method holds promise for improving the quality of life and health outcomes for individuals with Type 1 diabetes by providing a more responsive and precise management tool. Simulation results are given to highlight the effectiveness of the proposed approach.
Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 5 of its 29 references that are in the map. First posted on arXiv 9 Mar 2025.
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References · 5
- 2017Proximal Policy Optimization Algorithmscited by 15,215
- 2015Continuous control with deep reinforcement learningcited by 3,407
- 2016Asynchronous Methods for Deep Reinforcement Learningcited by 2,258
- 2019When to Trust Your Model: Model-Based Policy Optimizationcited by 773
- 2022Modern Machine Learning Tools for Monitoring and Control of Industrial Processes: A Surveycited by 6
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- 2026Application of Deep Reinforcement Learning to Event-Triggered Control for Networked Artificial Pancreas Systems
- 2025Integrating Neural Differential Forecasting with Safe Reinforcement Learning for Blood Glucose Regulation
- 2025The Role of Artificial Intelligence in Enhancing Insulin Recommendations and Therapy Outcomes
- 2024Blood Glucose Control Via Pre-trained Counterfactual Invertible Neural Networks
- 2026GUIDE: Reinforcement Learning for Behavioral Action Support in Type 1 Diabetes
- 2020MPC-guided Imitation Learning of Neural Network Policies for the Artificial Pancreas
- 2026Interpretable Language Model for Closed-Loop Type 1 Diabetes Control
- 2024An Improved Strategy for Blood Glucose Control Using Multi-Step Deep Reinforcement Learning