mlsanityData to 14 Oct 2026

Understanding the Impact of Confidence in Retrieval Augmented Generation: A Case Study in the Medical Domain

arXiv 2412.20309 ↗First posted 29 Dec 2024cs.CLcited by 9

On the map: Retrieval-augmented generation → RAG pipeline design and evaluation

Abstract (arXiv)

Retrieval Augmented Generation (RAG) complements the knowledge of Large Language Models (LLMs) by leveraging external information to enhance response accuracy for queries. This approach is widely applied in several fields by taking its advantage of injecting the most up-to-date information, and researchers are focusing on understanding and improving this aspect to unlock the full potential of RAG in such high-stakes applications. However, despite the potential of RAG to address these needs, the mechanisms behind the confidence levels of its outputs remain underexplored. Our study focuses on the impact of RAG, specifically examining whether RAG improves the confidence of LLM outputs in the medical domain. We conduct this analysis across various configurations and models. We evaluate confidence by treating the model's predicted probability as its output and calculating several evaluation metrics which include calibration error method, entropy, the best probability, and accuracy. Experimental results across multiple datasets confirmed that certain models possess the capability to judge for themselves whether an inserted document relates to the correct answer. These results suggest that evaluating models based on their output probabilities determine whether they function as generators in the RAG framework. Our approach allows us to evaluate whether the models handle retrieved documents.

Key facts. Cited by 9 papers in the map (data through 14 Oct 2026). Placed in RAG pipeline design and evaluation, one of 15 directions in Retrieval-augmented generation. Builds on 26 of its 43 references that are in the map. First posted on arXiv 29 Dec 2024.

Builds on

26 of 43 references.

Closest ancestors · 1

Same direction, newest first

  1. 2024Improving Retrieval for RAG based Question Answering Models on Financial Documents23 Mar

Other references · 25

  1. 2023GPT-4 Technical Reportcited by 18,396
  2. 2024The Llama 3 Herd of Modelscited by 14,715
  3. 2023LLaMA: Open and Efficient Foundation Language Modelscited by 14,132
  4. 2020Retrieval-Augmented Generation for Knowledge-Intensive NLP Taskscited by 9,297
  5. 2017On Calibration of Modern Neural Networkscited by 4,960
  6. 2023Lost in the Middle: How Language Models Use Long Contextscited by 3,455
  7. 2024Gemma 2: Improving Open Language Models at a Practical Sizecited by 1,998
  8. 2024Phi-3 Technical Report: A Highly Capable Language Model Locally on Your Phonecited by 1,917
  9. 2023Self-RAG: Learning to Retrieve, Generate, and Critique through Self-Reflectioncited by 1,839
  10. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
  11. 2019Measuring Calibration in Deep Learningcited by 446
  12. 2020How Can We Know When Language Models Know? On the Calibration of Language Models for Question Answeringcited by 445
13 more
  1. 2019Beyond temperature scaling: Obtaining well-calibrated multiclass probabilities with Dirichlet calibrationcited by 364
  2. 2024Benchmarking Retrieval-Augmented Generation for Medicinecited by 331
  3. 2019Verified Uncertainty Calibrationcited by 309
  4. 2023A Survey of Confidence Estimation and Calibration in Large Language Modelscited by 256
  5. 2023LM-Polygraph: Uncertainty Estimation for Language Modelscited by 131
  6. 2023SAC3: Reliable Hallucination Detection in Black-Box Language Models via Semantic-aware Cross-check Consistencycited by 90
  7. 2022Stop Measuring Calibration When Humans Disagreecited by 71
  8. 2024Rationale-Guided Retrieval Augmented Generation for Medical Question Answeringcited by 41
  9. 2024LLM-jp: A Cross-organizational Project for the Research and Development of Fully Open Japanese LLMscited by 33
  10. 2024Cycles of Thought: Measuring LLM Confidence through Stable Explanationscited by 29
  11. 2022Exploring Predictive Uncertainty and Calibration in NLP: A Study on the Impact of Method & Data Scarcitycited by 25
  12. 2024Controlling Risk of Retrieval-augmented Generation: A Counterfactual Prompting Frameworkcited by 12
  13. 2024Can We Trust the Performance Evaluation of Uncertainty Estimation Methods in Text Summarization?cited by 3

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 6; 2026: 3.

9 papers.

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Close in wording, no citation either way

  1. 2025Rethinking Retrieval-Augmented Generation for Medicine: A Large-Scale, Systematic Expert Evaluation and Practical Insights
  2. 2024Development and Testing of Retrieval Augmented Generation in Large Language Models -- A Case Study Report
  3. 2024Retrieval-Augmented Generation with Estimation of Source Reliability
  4. 2024Deploying Large Language Models With Retrieval Augmented Generation
  5. 2025Retrieval-Augmented Generation in Medicine: A Scoping Review of Technical Implementations, Clinical Applications, and Ethical Considerations
  6. 2025Towards Trustworthy Retrieval Augmented Generation for Large Language Models: A Survey
  7. 2024Towards Understanding Systems Trade-offs in Retrieval-Augmented Generation Model Inference
  8. 2025Retrieval Augmented Generation Evaluation in the Era of Large Language Models: A Comprehensive Survey