MixPE: Quantization and Hardware Co-design for Efficient LLM Inference
On the map: Efficient LLM inference and serving → KV cache quantization
Abstract (arXiv)
Transformer-based large language models (LLMs) have achieved remarkable success as model sizes continue to grow, yet their deployment remains challenging due to significant computational and memory demands. Quantization has emerged as a promising solution, and state-of-the-art quantization algorithms for LLMs introduce the need for mixed-precision matrix multiplication (mpGEMM), where lower-precision weights are multiplied with higher-precision activations. Despite its benefits, current hardware accelerators such as GPUs and TPUs lack native support for efficient mpGEMM, leading to inefficient dequantization operations in the main sequential loop. To address this limitation, we introduce MixPE, a specialized mixed-precision processing element designed for efficient low-bit quantization in LLM inference. MixPE leverages two key innovations to minimize dequantization overhead and unlock the full potential of low-bit quantization. First, recognizing that scale and zero point are shared within each quantization group, we propose performing dequantization after per-group mpGEMM, significantly reducing dequantization overhead. Second, instead of relying on conventional multipliers, MixPE utilizes efficient shift&add operations for multiplication, optimizing both computation and energy efficiency. Our experimental results demonstrate that MixPE surpasses the state-of-the-art quantization accelerators by 2.6× speedup and 1.4× energy reduction.
Key facts. Cited by 5 papers in the map (data through 14 Oct 2026). Placed in KV cache quantization, one of 12 directions in Efficient LLM inference and serving. Builds on 17 of its 29 references that are in the map. First posted on arXiv 25 Nov 2024.
Builds on
17 of 29 references.
Closest ancestors · 2
Same direction, newest first
- 2024QServe: W4A8KV4 Quantization and System Co-design for Efficient LLM Serving7 May
- 2023Atom: Low-bit Quantization for Efficient and Accurate LLM Serving29 Oct
Other references · 15
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
- 2024The Llama 3 Herd of Modelscited by 14,715
- 2023Llama 2: Open Foundation and Fine-Tuned Chat Modelscited by 13,028
- 2022OPT: Open Pre-trained Transformer Language Modelscited by 3,512
- 2020The Pile: An 800GB Dataset of Diverse Text for Language Modelingcited by 2,411
- 2023AWQ: Activation-aware Weight Quantization for LLM Compression and Accelerationcited by 1,298
- 2017In-Datacenter Performance Analysis of a Tensor Processing Unitcited by 618
- 2022ZeroQuant: Efficient and Affordable Post-Training Quantization for Large-Scale Transformerscited by 526
- 2021A White Paper on Neural Network Quantizationcited by 472
- 2024The Era of 1-bit LLMs: All Large Language Models are in 1.58 Bitscited by 308
- 2020SpAtten: Efficient Sparse Attention Architecture with Cascade Token and Head Pruningcited by 234
- 2017Bit Fusion: Bit-Level Dynamically Composable Architecture for Accelerating Deep Neural Networkscited by 109
3 more
- 2022LUT-GEMM: Quantized Matrix Multiplication based on LUTs for Efficient Inference in Large-Scale Generative Language Modelscited by 105
- 2023OliVe: Accelerating Large Language Models via Hardware-friendly Outlier-Victim Pair Quantizationcited by 92
- 2023Look-Up mAI GeMM: Increasing AI GeMMs Performance by Nearly 2.5x via msGeMMcited by 3
Built on by
Citing papers per year: 2025: 2; 2026: 3.
5 papers.
- 2025Toward Cybersecurity-Expert Small Language Modelscited by 4
- 2025Towards Efficient and Accurate Spiking Neural Networks via Adaptive Bit Allocationcited by 2
- 2026Unleashing Low-Bit Inference on Ascend NPUs: A Comprehensive Evaluation of HiFloat Formatscited by 2
- 2026Multi-Scale Dequant: Eliminating Dequantization Bottleneck via Activation Decomposition for Efficient LLM Inferencecited by 1
- 2026StreamDQ: Near-Memory Weight DeQuantization in Custom HBM for Scalable AI Inference Accelerationcited by 0
- 2026StreamDQ: Near-Memory Weight DeQuantization in Custom HBM for Scalable AI Inference Acceleration9 Jul 2026
- 2026Multi-Scale Dequant: Eliminating Dequantization Bottleneck via Activation Decomposition for Efficient LLM Inference13 May 2026
- 2026Unleashing Low-Bit Inference on Ascend NPUs: A Comprehensive Evaluation of HiFloat Formats13 Feb 2026
- 2025Toward Cybersecurity-Expert Small Language Models15 Oct 2025
- 2025Towards Efficient and Accurate Spiking Neural Networks via Adaptive Bit Allocation30 Jun 2025
Similar, not cited
Close in wording, no citation either way
- 2024LLMEasyQuant: Scalable Quantization for Parallel and Distributed LLM Inference
- 2025FGMP: Fine-Grained Mixed-Precision Weight and Activation Quantization for Hardware-Accelerated LLM Inference
- 2024QUICK: Quantization-aware Interleaving and Conflict-free Kernel for efficient LLM inference
- 2025FineQ: Software-Hardware Co-Design for Low-Bit Fine-Grained Mixed-Precision Quantization of LLMs
- 2023Fast and Efficient 2-bit LLM Inference on GPU: 2/4/16-bit in a Weight Matrix with Asynchronous Dequantization
- 2024DecDEC: A Systems Approach to Advancing Low-Bit LLM Quantization
- 2024LUT Tensor Core: A Software-Hardware Co-Design for LUT-Based Low-Bit LLM Inference
- 2023FineQuant: Unlocking Efficiency with Fine-Grained Weight-Only Quantization for LLMs