AXIS: Efficient Human-Agent-Computer Interaction with API-First LLM-Based Agents
On the map: LLM agents and tool use → GUI and mobile agents
Abstract (arXiv)
Multimodal large language models (MLLMs) have enabled LLM-based agents to directly interact with application user interfaces (UIs), enhancing agents' performance in complex tasks. However, these agents often suffer from high latency and low reliability due to the extensive sequential UI interactions. To address this issue, we propose AXIS, a novel LLM-based agents framework that prioritize actions through application programming interfaces (APIs) over UI actions. This framework also facilitates the creation and expansion of APIs through automated exploration of applications. Our experiments on Microsoft Word demonstrate that AXIS reduces task completion time by 65%-70% and cognitive workload by 38%-53%, while maintaining accuracy of 97%-98% compared to humans. Our work contributes to a new human-agent-computer interaction (HACI) framework and explores a fresh UI design principle for application providers to turn applications into agents in the era of LLMs, paving the way towards an agent-centric operating system (Agent OS).
Key facts. Cited by 11 papers in the map (data through 7 Oct 2026). Placed in GUI and mobile agents, one of 16 directions in LLM agents and tool use. Builds on 24 of its 164 references that are in the map. First posted on arXiv 25 Sep 2024.
Builds on
24 of 164 references.
Closest ancestors · 5
Same direction, newest first
- 2024OSWorld: Benchmarking Multimodal Agents for Open-Ended Tasks in Real Computer Environments11 Apr
- 2024Mobile-Agent: Autonomous Multi-Modal Mobile Device Agent with Visual Perception29 Jan
- 2024SeeClick: Harnessing GUI Grounding for Advanced Visual GUI Agents17 Jan
- 2023AppAgent: Multimodal Agents as Smartphone Users21 Dec
- 2023CogAgent: A Visual Language Model for GUI Agents14 Dec
Other references · 19
- 2023GPT-4 Technical Reportcited by 18,132
- 2022Training language models to follow instructions with human feedbackcited by 15,712
- 2024The Llama 3 Herd of Modelscited by 14,192
- 2023A Survey on Large Language Model based Autonomous Agentscited by 2,203
- 2023Qwen-VL: A Versatile Vision-Language Model for Understanding, Localization, Text Reading, and Beyondcited by 2,179
- 2023The Rise and Potential of Large Language Model Based Agents: A Surveycited by 1,422
- 2023A Multitask, Multilingual, Multimodal Evaluation of ChatGPT on Reasoning, Hallucination, and Interactivitycited by 888
- 2023The Dawn of LMMs: Preliminary Explorations with GPT-4V(ision)cited by 677
- 2024GPT-4V(ision) is a Generalist Web Agent, if Groundedcited by 547
- 2024AndroidWorld: A Dynamic Benchmarking Environment for Autonomous Agentscited by 450
- 2023Large Language Models as Tool Makerscited by 293
- 2023Large Language Models as Commonsense Knowledge for Large-Scale Task Planningcited by 231
7 more
- 2024Extreme Compression of Large Language Models via Additive Quantizationcited by 223
- 2024UFO: A UI-Focused Agent for Windows OS Interactioncited by 147
- 2023GPT-4V in Wonderland: Large Multimodal Models for Zero-Shot Smartphone GUI Navigationcited by 137
- 2023Can GPT-4V(ision) Serve Medical Applications? Case Studies on GPT-4V for Multimodal Medical Diagnosiscited by 77
- 2017Agile Software Development Methods: Review and Analysiscited by 18
- 2024MUD: Towards a Large-Scale and Noise-Filtered UI Dataset for Modern Style UI Modelingcited by 9
- 2024The Vision of Autonomic Computing: Can LLMs Make It a Reality?cited by 4
Built on by
Citing papers per year: 2024: 1; 2025: 7; 2026: 3.
11 papers.
- 2024Large Language Model-Brained GUI Agents: A Surveycited by 160
- 2025A Survey of Self-Evolving Agents: What, When, How, and Where to Evolve on the Path to Artificial Super Intelligencecited by 155
- 2025A Survey of Context Engineering for Large Language Modelscited by 120
- 2026MobilityBench: A Benchmark for Evaluating Route-Planning Agents in Real-World Mobility Scenarioscited by 8
- 2025Large Language Models as Computable Approximations to Solomonoff Inductioncited by 6
- 2026Terminal Agents Suffice for Enterprise Automationcited by 5
- 2025Every Software as an Agent: Blueprint and Case Studycited by 2
- 2025From Imperative to Declarative: Towards LLM-friendly OS Interfaces for Boosted Computer-Use Agentscited by 2
- 2025Enabling Autonomic Microservice Management through Self-Learning Agentscited by 1
- 2026Trustworthy Agent Network: Trust in Agent Networks Must Be Baked In, Not Bolted Oncited by 1
- 2025A Multimodal GUI Architecture for Interfacing with LLM-Based Conversational Assistantscited by 0
- 2026Trustworthy Agent Network: Trust in Agent Networks Must Be Baked In, Not Bolted On18 May 2026
- 2026Terminal Agents Suffice for Enterprise Automation31 Mar 2026
- 2026MobilityBench: A Benchmark for Evaluating Route-Planning Agents in Real-World Mobility Scenarios26 Feb 2026
- 2025From Imperative to Declarative: Towards LLM-friendly OS Interfaces for Boosted Computer-Use Agents6 Oct 2025
- 2025A Multimodal GUI Architecture for Interfacing with LLM-Based Conversational Assistants31 Aug 2025
- 2025A Survey of Self-Evolving Agents: What, When, How, and Where to Evolve on the Path to Artificial Super Intelligence28 Jul 2025
- 2025A Survey of Context Engineering for Large Language Models17 Jul 2025
- 2025Large Language Models as Computable Approximations to Solomonoff Induction21 May 2025
- 2025Every Software as an Agent: Blueprint and Case Study7 Feb 2025
- 2025Enabling Autonomic Microservice Management through Self-Learning Agents31 Jan 2025
- 2024Large Language Model-Brained GUI Agents: A Survey27 Nov 2024
Similar, not cited
Close in wording, no citation either way
- 2025API Agents vs. GUI Agents: Divergence and Convergence
- 2024Towards better Human-Agent Alignment: Assessing Task Utility in LLM-Powered Applications
- 2025Position: The Real Barrier to LLM Agent Usability is Agentic ROI
- 2024Windows Agent Arena: Evaluating Multi-Modal OS Agents at Scale
- 2025AppAgentX: Evolving GUI Agents as Proficient Smartphone Users
- 2025DuetUI: A Bidirectional Context Loop for Human-Agent Co-Generation of Task-Oriented Interfaces
- 2024GUI Agents with Foundation Models: A Comprehensive Survey
- 2024Human-Centered LLM-Agent User Interface: A Position Paper