Enhancing Depression Diagnosis with Chain-of-Thought Prompting
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Abstract (arXiv)
When using AI to detect signs of depressive disorder, AI models habitually draw preemptive conclusions. We theorize that using chain-of-thought (CoT) prompting to evaluate Patient Health Questionnaire-8 (PHQ-8) scores will improve the accuracy of the scores determined by AI models. In our findings, when the models reasoned with CoT, the estimated PHQ-8 scores were consistently closer on average to the accepted true scores reported by each participant compared to when not using CoT. Our goal is to expand upon AI models' understanding of the intricacies of human conversation, allowing them to more effectively assess a patient's feelings and tone, therefore being able to more accurately discern mental disorder symptoms; ultimately, we hope to augment AI models' abilities, so that they can be widely accessible and used in the medical field.
Key facts. Cited by 2 papers in the map (data through 14 Oct 2026). Builds on 2 of its 15 references that are in the map. First posted on arXiv 26 Aug 2024.
Builds on
2 of 15 references.
References · 2
- 2022Chain-of-Thought Prompting Elicits Reasoning in Large Language Modelscited by 12,459
- 2022Large Language Models are Zero-Shot Reasonerscited by 4,374
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Citing papers per year: 2025: 1; 2026: 1.
2 papers.
Similar, not cited
Close in wording, no citation either way
- 2025Enhancing Depression Detection with Chain-of-Thought Prompting: From Emotion to Reasoning Using Large Language Models
- 2026Fine-tuning LLMs for Passive Depression Severity Estimation from AI Mental Health Dialogue
- 2024InterMind: Doctor-Patient-Family Interactive Depression Assessment Empowered by Large Language Models
- 2023From Classification to Clinical Insights: Towards Analyzing and Reasoning About Mobile and Behavioral Health Data With Large Language Models
- 2025Systematic Evaluation of Machine-Generated Reasoning and PHQ-9 Labeling for Depression Detection Using Large Language Models
- 2026Dep-LLM: Training-Free Depression Diagnosis via Evidence-Guided Structured Multi-factor with Reliable LLM Reasoning
- 2026Structure vs. Chain-of-Thought: Evaluating LLM Criteria Extraction for Depression Severity
- 2025Prompting Science Report 2: The Decreasing Value of Chain of Thought in Prompting