Identity-Consistent Diffusion Network for Grading Knee Osteoarthritis Progression in Radiographic Imaging
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Abstract (arXiv)
Knee osteoarthritis (KOA), a common form of arthritis that causes physical disability, has become increasingly prevalent in society. Employing computer-aided techniques to automatically assess the severity and progression of KOA can greatly benefit KOA treatment and disease management. Particularly, the advancement of X-ray technology in KOA demonstrates its potential for this purpose. Yet, existing X-ray prognosis research generally yields a singular progression severity grade, overlooking the potential visual changes for understanding and explaining the progression outcome. Therefore, in this study, a novel generative model is proposed, namely Identity-Consistent Radiographic Diffusion Network (IC-RDN), for multifaceted KOA prognosis encompassing a predicted future knee X-ray scan conditioned on the baseline scan. Specifically, an identity prior module for the diffusion and a downstream generation-guided progression prediction module are introduced. Compared to conventional image-to-image generative models, identity priors regularize and guide the diffusion to focus more on the clinical nuances of the prognosis based on a contrastive learning strategy. The progression prediction module utilizes both forecasted and baseline knee scans, and a more comprehensive formulation of KOA severity progression grading is expected. Extensive experiments on a widely used public dataset, OAI, demonstrate the effectiveness of the proposed method.
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References · 18
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6 more
- 2020Semixup: In- and Out-of-Manifold Regularization for Deep Semi-Supervised Knee Osteoarthritis Severity Grading from Plain Radiographscited by 8
- 2019Assessing Knee OA Severity with CNN attention-based end-to-end architecturescited by 6
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- 2023Exploring the Efficacy of Base Data Augmentation Methods in Deep Learning-Based Radiograph Classification of Knee Joint Osteoarthritiscited by 3
- 2019Towards Shape-based Knee Osteoarthritis Classification using Graph Convolutional Networkscited by 2
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