FMDNN: A Fuzzy-guided Multi-granular Deep Neural Network for Histopathological Image Classification
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Abstract (arXiv)
Histopathological image classification constitutes a pivotal task in computer-aided diagnostics. The precise identification and categorization of histopathological images are of paramount significance for early disease detection and treatment. In the diagnostic process of pathologists, a multi-tiered approach is typically employed to assess abnormalities in cell regions at different magnifications. However, feature extraction is often performed at a single granularity, overlooking the multi-granular characteristics of cells. To address this issue, we propose the Fuzzy-guided Multi-granularity Deep Neural Network (FMDNN). Inspired by the multi-granular diagnostic approach of pathologists, we perform feature extraction on cell structures at coarse, medium, and fine granularity, enabling the model to fully harness the information in histopathological images. We incorporate the theory of fuzzy logic to address the challenge of redundant key information arising during multi-granular feature extraction. Cell features are described from different perspectives using multiple fuzzy membership functions, which are fused to create universal fuzzy features. A fuzzy-guided cross-attention module guides universal fuzzy features toward multi-granular features. We propagate these features through an encoder to all patch tokens, aiming to achieve enhanced classification accuracy and robustness. In experiments on multiple public datasets, our model exhibits a significant improvement in accuracy over commonly used classification methods for histopathological image classification and shows commendable interpretability.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 26 of its 63 references that are in the map. First posted on arXiv 22 Jul 2024.
Builds on
26 of 63 references.
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Citing papers per year: 2025: 2; 2026: 1.
3 papers.
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- 2026FedHisto-PAST: Parameter-Efficient Stain-Aware Federated Learning for Cross-Site Lung Histopathology Classificationcited by 0
- 2026FedHisto-PAST: Parameter-Efficient Stain-Aware Federated Learning for Cross-Site Lung Histopathology Classification25 Sep 2026
- 2025MMLNB: Multi-Modal Learning for Neuroblastoma Subtyping Classification Assisted with Textual Description Generation17 Mar 2025
- 2025Vision Transformer for Intracranial Hemorrhage Classification in CT Scans Using an Entropy-Aware Fuzzy Integral Strategy for Adaptive Scan-Level Decision Fusion11 Mar 2025