mlsanityData to 7 Oct 2026

SegFormer3D: an Efficient Transformer for 3D Medical Image Segmentation

arXiv 2404.10156 ↗First posted 15 Apr 2024cs.CVcited by 31

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Abstract (arXiv)

The adoption of Vision Transformers (ViTs) based architectures represents a significant advancement in 3D Medical Image (MI) segmentation, surpassing traditional Convolutional Neural Network (CNN) models by enhancing global contextual understanding. While this paradigm shift has significantly enhanced 3D segmentation performance, state-of-the-art architectures require extremely large and complex architectures with large scale computing resources for training and deployment. Furthermore, in the context of limited datasets, often encountered in medical imaging, larger models can present hurdles in both model generalization and convergence. In response to these challenges and to demonstrate that lightweight models are a valuable area of research in 3D medical imaging, we present SegFormer3D, a hierarchical Transformer that calculates attention across multiscale volumetric features. Additionally, SegFormer3D avoids complex decoders and uses an all-MLP decoder to aggregate local and global attention features to produce highly accurate segmentation masks. The proposed memory efficient Transformer preserves the performance characteristics of a significantly larger model in a compact design. SegFormer3D democratizes deep learning for 3D medical image segmentation by offering a model with 33x less parameters and a 13x reduction in GFLOPS compared to the current state-of-the-art (SOTA). We benchmark SegFormer3D against the current SOTA models on three widely used datasets Synapse, BRaTs, and ACDC, achieving competitive results. Code: https://github.com/OSUPCVLab/SegFormer3D.git

Key facts. Cited by 31 papers in the map (data through 7 Oct 2026). Builds on 25 of its 35 references that are in the map. First posted on arXiv 15 Apr 2024.

Builds on

25 of 35 references.

References · 25

  1. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
  2. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  3. 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,845
  4. 2021SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformerscited by 2,923
  5. 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
  6. 2021Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutionscited by 1,960
  7. 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
  8. 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
  9. 2020Rethinking Semantic Segmentation from a Sequence-to-Sequence Perspective with Transformerscited by 1,368
  10. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
  11. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
  12. 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 823
13 more
  1. 2018nnU-Net: Self-adapting Framework for U-Net-Based Medical Image Segmentationcited by 291
  2. 2021TransBTS: Multimodal Brain Tumor Segmentation Using Transformercited by 265
  3. 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
  4. 2021CoTr: Efficiently Bridging CNN and Transformer for 3D Medical Image Segmentationcited by 227
  5. 2023EfficientViT: Memory Efficient Vision Transformer with Cascaded Group Attentioncited by 172
  6. 2020How Much Position Information Do Convolutional Neural Networks Encode?cited by 171
  7. 2021LeViT-UNet: Make Faster Encoders with Transformer for Medical Image Segmentationcited by 85
  8. 20163D Deeply Supervised Network for Automatic Liver Segmentation from CT Volumescited by 43
  9. 2021TransClaw U-Net: Claw U-Net with Transformers for Medical Image Segmentationcited by 41
  10. 2017Deeply-Supervised CNN for Prostate Segmentationcited by 30
  11. 2017Hierarchical 3D fully convolutional networks for multi-organ segmentationcited by 19
  12. 2024Masked LoGoNet: Fast and Accurate 3D Image Analysis for Medical Domaincited by 6
  13. 2020PGD-UNet: A Position-Guided Deformable Network for Simultaneous Segmentation of Organs and Tumorscited by 5

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2024: 6; 2025: 18; 2026: 7.

31 papers.

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  1. 2024DetailCLIP: Detail-Oriented CLIP for Fine-Grained Taskscited by 15
  2. 2025Citrus-V: Advancing Medical Foundation Models with Unified Medical Image Grounding for Clinical Reasoningcited by 8
  3. 2024MobileUNETR: A Lightweight End-To-End Hybrid Vision Transformer For Efficient Medical Image Segmentationcited by 6
  4. 2024KnobGen: Controlling the Sophistication of Artwork in Sketch-Based Diffusion Modelscited by 6
  5. 2025No More Sliding Window: Efficient 3D Medical Image Segmentation with Differentiable Top-k Patch Samplingcited by 5
  6. 2024Frequency-Guided Masking for Enhanced Vision Self-Supervised Learningcited by 4
  7. 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentationcited by 4
  8. 2025Federated nnU-Net for Privacy-Preserving Medical Image Segmentationcited by 3
  9. 2025FuseUNet: A Multi-Scale Feature Fusion Method for U-like Networkscited by 3
  10. 2024DocParseNet: Advanced Semantic Segmentation and OCR Embeddings for Efficient Scanned Document Annotationcited by 2
  11. 2025Interpretable Auto Window Setting for Deep-Learning-Based CT Analysiscited by 2
  12. 2025OmniMamba4D: Spatio-temporal Mamba for longitudinal CT lesion segmentationcited by 1
19 more
  1. 2025SegFormer Fine-Tuning with Dropout: Advancing Hair Artifact Removal in Skin Lesion Analysiscited by 1
  2. 2025Spatial-Aware Self-Supervision for Medical 3D Imaging with Multi-Granularity Observable Taskscited by 1
  3. 2025Frequency-Aware Ensemble Learning for BraTS 2025 Pediatric Brain Tumor Segmentationcited by 1
  4. 2026Beyond a Single Frame: Multi-Frame Spatially Grounded Reasoning Across Volumetric MRIcited by 1
  5. 2026SEMIR: Semantic Minor-Induced Representation Learning on Graphs for Visual Segmentationcited by 1
  6. 2024Higher-Order Transformers With Kronecker-Structured Attentioncited by 0
  7. 2025IntelliCardiac: An Intelligent Platform for Cardiac Image Segmentation and Classificationcited by 0
  8. 2025GaMNet: A Hybrid Network with Gabor Fusion and NMamba for Efficient 3D Glioma Segmentationcited by 0
  9. 2025DM-SegNet: Dual-Mamba Architecture for 3D Medical Image Segmentation with Global Context Modelingcited by 0
  10. 2025Graph-Based Multi-Modal Light-weight Network for Adaptive Brain Tumor Segmentationcited by 0
  11. 2025ASM-UNet: Adaptive Scan Mamba Integrating Group Commonalities and Individual Variations for Fine-Grained Segmentationcited by 0
  12. 2025Johnson-Lindenstrauss Lemma Guided Network for Efficient 3D Medical Segmentationcited by 0
  13. 2025PF-DAformer: Proximal Femur Segmentation via Domain Adaptive Transformer for Dual-Center QCTcited by 0
  14. 2025Breast Cancer Neoadjuvant Chemotherapy Treatment Response Prediction Using Aligned Longitudinal MRI and Clinical Datacited by 0
  15. 2026RefineFormer3D: Efficient 3D Medical Image Segmentation via Adaptive Multi-Scale Transformer with Cross Attention Fusioncited by 0
  16. 2026ILV: Iterative Latent Volumes for Fast and Accurate Sparse-View CT Reconstructioncited by 0
  17. 2026SegMaFormer: A Hybrid State-Space and Transformer Model for Efficient Segmentationcited by 0
  18. 2026GPAFormer: Graph-guided Patch Aggregation Transformer for Efficient 3D Medical Image Segmentationcited by 0
  19. 2026TRACE-Seg3D: Counterfactual Context Auditing For Robust 3D Glioma Segmentation Under Institutional Shiftcited by 0