Medical mT5: An Open-Source Multilingual Text-to-Text LLM for The Medical Domain
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Abstract (arXiv)
Research on language technology for the development of medical applications is currently a hot topic in Natural Language Understanding and Generation. Thus, a number of large language models (LLMs) have recently been adapted to the medical domain, so that they can be used as a tool for mediating in human-AI interaction. While these LLMs display competitive performance on automated medical texts benchmarks, they have been pre-trained and evaluated with a focus on a single language (English mostly). This is particularly true of text-to-text models, which typically require large amounts of domain-specific pre-training data, often not easily accessible for many languages. In this paper, we address these shortcomings by compiling, to the best of our knowledge, the largest multilingual corpus for the medical domain in four languages, namely English, French, Italian and Spanish. This new corpus has been used to train Medical mT5, the first open-source text-to-text multilingual model for the medical domain. Additionally, we present two new evaluation benchmarks for all four languages with the aim of facilitating multilingual research in this domain. A comprehensive evaluation shows that Medical mT5 outperforms both encoders and similarly sized text-to-text models for the Spanish, French, and Italian benchmarks, while being competitive with current state-of-the-art LLMs in English.
Key facts. Cited by 15 papers in the map (data through 7 Oct 2026). Builds on 21 of its 39 references that are in the map. First posted on arXiv 11 Apr 2024.
Builds on
21 of 39 references.
References · 21
- 2017Attention Is All You Needcited by 59,932
- 2020Language Models are Few-Shot Learnerscited by 32,199
- 2019Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformercited by 14,491
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2023LLaMA: Open and Efficient Foundation Language Modelscited by 13,958
- 2019Unsupervised Cross-lingual Representation Learning at Scalecited by 3,907
- 2022Scaling Instruction-Finetuned Language Modelscited by 2,997
- 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,935
- 2020mT5: A massively multilingual pre-trained text-to-text transformercited by 1,813
- 2022Large Language Models Encode Clinical Knowledgecited by 1,807
- 2019SciBERT: A Pretrained Language Model for Scientific Textcited by 1,404
- 2022No Language Left Behind: Scaling Human-Centered Machine Translationcited by 1,290
9 more
- 2021DeBERTaV3: Improving DeBERTa using ELECTRA-Style Pre-Training with Gradient-Disentangled Embedding Sharingcited by 1,219
- 2022BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Miningcited by 531
- 2022LinkBERT: Pretraining Language Models with Document Linkscited by 209
- 2023Glot500: Scaling Multilingual Corpora and Language Models to 500 Languagescited by 116
- 2021SciFive: a text-to-text transformer model for biomedical literaturecited by 99
- 2023PMC-LLaMA: Towards Building Open-source Language Models for Medicinecited by 87
- 2023ClinicalGPT: Large Language Models Finetuned with Diverse Medical Data and Comprehensive Evaluationcited by 85
- 2022T-Projection: High Quality Annotation Projection for Sequence Labeling Taskscited by 14
- 2022Lessons learned from the evaluation of Spanish Language Modelscited by 8
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Citing papers per year: 2024: 4; 2025: 7; 2026: 4.
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- 2024KG4Diagnosis: A Hierarchical Multi-Agent LLM Framework with Knowledge Graph Enhancement for Medical Diagnosiscited by 26
- 2024Multilingual Large Language Models: A Systematic Surveycited by 18
- 2025Towards User-level Private Reinforcement Learning with Human Feedbackcited by 13
- 2024CasiMedicos-Arg: A Medical Question Answering Dataset Annotated with Explanatory Argumentative Structurescited by 11
- 2025Document Intelligence in the Era of Large Language Models: A Surveycited by 5
- 2025Leveraging Online Data to Enhance Medical Knowledge in a Small Persian Language Modelcited by 3
- 2025MoFE: Mixture of Frozen Experts Architecturecited by 1
- 2025RigoChat 2: an adapted language model to Spanish using a bounded dataset and reduced hardwarecited by 1
- 2025Pruning General Large Language Models into Customized Expert Modelscited by 1
- 2026Measuring Distribution Shift in User Prompts and Its Effects on LLM Performancecited by 1
- 2024Retrieve, Generate, Evaluate: A Case Study for Medical Paraphrases Generation with Small Language Modelscited by 0
- 2025A Perplexity and Menger Curvature-Based Approach for Similarity Evaluation of Large Language Modelscited by 0
- 2026Gaokerena: A Small Persian Medical Language Model Family2 Aug 2026
- 2026Trade-offs in Medical LLM Adaptation: An Empirical Study in French QA17 Jun 2026
- 2026Measuring Distribution Shift in User Prompts and Its Effects on LLM Performance19 Apr 2026
- 2026Evaluating Fine-Tuned LLM Model For Medical Transcription With Small Low-Resource Languages Validated Dataset25 Mar 2026
- 2025Document Intelligence in the Era of Large Language Models: A Survey15 Oct 2025
- 2025Pruning General Large Language Models into Customized Expert Models3 Jun 2025
- 2025Leveraging Online Data to Enhance Medical Knowledge in a Small Persian Language Model21 May 2025
- 2025A Perplexity and Menger Curvature-Based Approach for Similarity Evaluation of Large Language Models5 Apr 2025
- 2025RigoChat 2: an adapted language model to Spanish using a bounded dataset and reduced hardware11 Mar 2025
- 2025MoFE: Mixture of Frozen Experts Architecture9 Mar 2025
- 2025Towards User-level Private Reinforcement Learning with Human Feedback22 Feb 2025
- 2024KG4Diagnosis: A Hierarchical Multi-Agent LLM Framework with Knowledge Graph Enhancement for Medical Diagnosis22 Dec 2024
3 more
- 2024Multilingual Large Language Models: A Systematic Survey17 Nov 2024
- 2024CasiMedicos-Arg: A Medical Question Answering Dataset Annotated with Explanatory Argumentative Structures7 Oct 2024
- 2024Retrieve, Generate, Evaluate: A Case Study for Medical Paraphrases Generation with Small Language Models23 Jul 2024
- 2025MoFE: Mixture of Frozen Experts Architecturecited by 1
- 2025MoFE: Mixture of Frozen Experts Architecture9 Mar 2025
- 2024Multilingual Large Language Models: A Systematic Surveycited by 18
- 2024CasiMedicos-Arg: A Medical Question Answering Dataset Annotated with Explanatory Argumentative Structurescited by 11
- 2025Document Intelligence in the Era of Large Language Models: A Surveycited by 5
- 2025Leveraging Online Data to Enhance Medical Knowledge in a Small Persian Language Modelcited by 3
- 2025RigoChat 2: an adapted language model to Spanish using a bounded dataset and reduced hardwarecited by 1
- 2025Pruning General Large Language Models into Customized Expert Modelscited by 1
- 2026Measuring Distribution Shift in User Prompts and Its Effects on LLM Performancecited by 1
- 2024Retrieve, Generate, Evaluate: A Case Study for Medical Paraphrases Generation with Small Language Modelscited by 0
- 2025A Perplexity and Menger Curvature-Based Approach for Similarity Evaluation of Large Language Modelscited by 0
- 2026Evaluating Fine-Tuned LLM Model For Medical Transcription With Small Low-Resource Languages Validated Datasetcited by 0
- 2026Trade-offs in Medical LLM Adaptation: An Empirical Study in French QAcited by 0
- 2026Gaokerena: A Small Persian Medical Language Model Familycited by 0
- 2026Gaokerena: A Small Persian Medical Language Model Family2 Aug 2026
- 2026Trade-offs in Medical LLM Adaptation: An Empirical Study in French QA17 Jun 2026
- 2026Measuring Distribution Shift in User Prompts and Its Effects on LLM Performance19 Apr 2026
- 2026Evaluating Fine-Tuned LLM Model For Medical Transcription With Small Low-Resource Languages Validated Dataset25 Mar 2026
- 2025Document Intelligence in the Era of Large Language Models: A Survey15 Oct 2025
- 2025Pruning General Large Language Models into Customized Expert Models3 Jun 2025
- 2025Leveraging Online Data to Enhance Medical Knowledge in a Small Persian Language Model21 May 2025
- 2025A Perplexity and Menger Curvature-Based Approach for Similarity Evaluation of Large Language Models5 Apr 2025
- 2025RigoChat 2: an adapted language model to Spanish using a bounded dataset and reduced hardware11 Mar 2025
- 2024Multilingual Large Language Models: A Systematic Survey17 Nov 2024
- 2024CasiMedicos-Arg: A Medical Question Answering Dataset Annotated with Explanatory Argumentative Structures7 Oct 2024
- 2024Retrieve, Generate, Evaluate: A Case Study for Medical Paraphrases Generation with Small Language Models23 Jul 2024