Developing ChatGPT for Biology and Medicine: A Complete Review of Biomedical Question Answering
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Abstract (arXiv)
ChatGPT explores a strategic blueprint of question answering (QA) in delivering medical diagnosis, treatment recommendations, and other healthcare support. This is achieved through the increasing incorporation of medical domain data via natural language processing (NLP) and multimodal paradigms. By transitioning the distribution of text, images, videos, and other modalities from the general domain to the medical domain, these techniques have expedited the progress of medical domain question answering (MDQA). They bridge the gap between human natural language and sophisticated medical domain knowledge or expert manual annotations, handling large-scale, diverse, unbalanced, or even unlabeled data analysis scenarios in medical contexts. Central to our focus is the utilizing of language models and multimodal paradigms for medical question answering, aiming to guide the research community in selecting appropriate mechanisms for their specific medical research requirements. Specialized tasks such as unimodal-related question answering, reading comprehension, reasoning, diagnosis, relation extraction, probability modeling, and others, as well as multimodal-related tasks like vision question answering, image caption, cross-modal retrieval, report summarization, and generation, are discussed in detail. Each section delves into the intricate specifics of the respective method under consideration. This paper highlights the structures and advancements of medical domain explorations against general domain methods, emphasizing their applications across different tasks and datasets. It also outlines current challenges and opportunities for future medical domain research, paving the way for continued innovation and application in this rapidly evolving field.
Key facts. Cited by 3 papers in the map (data through 7 Oct 2026). Builds on 44 of its 64 references that are in the map. First posted on arXiv 15 Jan 2024.
Builds on
44 of 64 references.
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Citing papers per year: 2025: 2; 2026: 1.
3 papers.
- 2025BALI: Enhancing Biomedical Language Representations through Knowledge Graph and Language Model Alignmentcited by 2
- 2025RAG-BioQA: A Retrieval-Augmented Generation Framework for Long-Form Biomedical Question Answeringcited by 0
- 2026From Single to Multi-Agent Reasoning: Advancing GeneGPT for Genomics QAcited by 0
- 2026From Single to Multi-Agent Reasoning: Advancing GeneGPT for Genomics QA15 Jan 2026
- 2025RAG-BioQA: A Retrieval-Augmented Generation Framework for Long-Form Biomedical Question Answering2 Oct 2025
- 2025BALI: Enhancing Biomedical Language Representations through Knowledge Graph and Language Model Alignment9 Sep 2025