mlsanityData to 7 Oct 2026

Ultra-Resolution Cascaded Diffusion Model for Gigapixel Image Synthesis in Histopathology

arXiv 2312.01152 ↗First posted 2 Dec 2023eess.IV cs.CVcited by 0

On the map: Diffusion models → Medical imaging and segmentation

Abstract (arXiv)

Diagnoses from histopathology images rely on information from both high and low resolutions of Whole Slide Images. Ultra-Resolution Cascaded Diffusion Models (URCDMs) allow for the synthesis of high-resolution images that are realistic at all magnification levels, focusing not only on fidelity but also on long-distance spatial coherency. Our model beats existing methods, improving the pFID-50k [2] score by 110.63 to 39.52 pFID-50k. Additionally, a human expert evaluation study was performed, reaching a weighted Mean Absolute Error (MAE) of 0.11 for the Lower Resolution Diffusion Models and a weighted MAE of 0.22 for the URCDM.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models. Builds on 6 of its 9 references that are in the map. First posted on arXiv 2 Dec 2023.

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6 of 9 references.

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Same direction, newest first

  1. 2023Feature-Conditioned Cascaded Video Diffusion Models for Precise Echocardiogram Synthesis22 Mar

Other references · 5

  1. 2021Alias-Free Generative Adversarial Networkscited by 1,181
  2. 2022Any-resolution Training for High-resolution Image Synthesiscited by 72
  3. 2018You Only Look Twice: Rapid Multi-Scale Object Detection In Satellite Imagerycited by 27
  4. 2022Federated Stain Normalization for Computational Pathologycited by 11
  5. 2023Realistic Data Enrichment for Robust Image Segmentation in Histopathologycited by 7

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  1. 2024URCDM: Ultra-Resolution Image Synthesis in Histopathology
  2. 2023Diffusion-based generation of Histopathological Whole Slide Images at a Gigapixel scale
  3. 2026Scale-Cascaded Diffusion Models for Super-Resolution in Medical Imaging
  4. 2022A Morphology Focused Diffusion Probabilistic Model for Synthesis of Histopathology Images
  5. 2024ZoomLDM: Latent Diffusion Model for multi-scale image generation
  6. 2024Cascaded Diffusion Models for 2D and 3D Microscopy Image Synthesis to Enhance Cell Segmentation
  7. 2025PathDiff: Histopathology Image Synthesis with Unpaired Text and Mask Conditions
  8. 2025Graph Conditioned Diffusion for Controllable Histopathology Image Generation