Test-time augmentation-based active learning and self-training for label-efficient segmentation
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Abstract (arXiv)
Deep learning techniques depend on large datasets whose annotation is time-consuming. To reduce annotation burden, the self-training (ST) and active-learning (AL) methods have been developed as well as methods that combine them in an iterative fashion. However, it remains unclear when each method is the most useful, and when it is advantageous to combine them. In this paper, we propose a new method that combines ST with AL using Test-Time Augmentations (TTA). First, TTA is performed on an initial teacher network. Then, cases for annotation are selected based on the lowest estimated Dice score. Cases with high estimated scores are used as soft pseudo-labels for ST. The selected annotated cases are trained with existing annotated cases and ST cases with border slices annotations. We demonstrate the method on MRI fetal body and placenta segmentation tasks with different data variability characteristics. Our results indicate that ST is highly effective for both tasks, boosting performance for in-distribution (ID) and out-of-distribution (OOD) data. However, while self-training improved the performance of single-sequence fetal body segmentation when combined with AL, it slightly deteriorated performance of multi-sequence placenta segmentation on ID data. AL was helpful for the high variability placenta data, but did not improve upon random selection for the single-sequence body data. For fetal body segmentation sequence transfer, combining AL with ST following ST iteration yielded a Dice of 0.961 with only 6 original scans and 2 new sequence scans. Results using only 15 high-variability placenta cases were similar to those using 50 cases. Code is available at: https://github.com/Bella31/TTA-quality-estimation-ST-AL
Key facts. Cited by 3 papers in the map (data through 14 Oct 2026). Builds on 17 of its 27 references that are in the map. First posted on arXiv 21 Aug 2023.
Builds on
17 of 27 references.
References · 17
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5 more
- 2019Assessing Reliability and Challenges of Uncertainty Estimations for Medical Image Segmentationcited by 75
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Citing papers per year: 2025: 1; 2026: 2.
3 papers.
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- 2026Nested Radially Monotone Polar Occupancy Estimation: Clinically-Grounded Optic Disc and Cup Segmentation for Glaucoma Screening10 Apr 2026
- 2026From Cold Start to Active Learning: Embedding-Based Scan Selection for Medical Image Segmentation26 Jan 2026
- 2025SingleStrip: learning skull-stripping from a single labeled example14 Aug 2025