LesionMix: A Lesion-Level Data Augmentation Method for Medical Image Segmentation
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Abstract (arXiv)
Data augmentation has become a de facto component of deep learning-based medical image segmentation methods. Most data augmentation techniques used in medical imaging focus on spatial and intensity transformations to improve the diversity of training images. They are often designed at the image level, augmenting the full image, and do not pay attention to specific abnormalities within the image. Here, we present LesionMix, a novel and simple lesion-aware data augmentation method. It performs augmentation at the lesion level, increasing the diversity of lesion shape, location, intensity and load distribution, and allowing both lesion populating and inpainting. Experiments on different modalities and different lesion datasets, including four brain MR lesion datasets and one liver CT lesion dataset, demonstrate that LesionMix achieves promising performance in lesion image segmentation, outperforming several recent Mix-based data augmentation methods. The code will be released at https://github.com/dogabasaran/lesionmix.
Key facts. Cited by 7 papers in the map (data through 13 Oct 2026). Builds on 17 of its 28 references that are in the map. First posted on arXiv 17 Aug 2023.
Builds on
17 of 28 references.
References · 17
- 2019CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Featurescited by 2,882
- 2019The Liver Tumor Segmentation Benchmark (LiTS)cited by 507
- 2019Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challengecited by 115
- 2021Does Your Dermatology Classifier Know What It Doesn't Know? Detecting the Long-Tail of Unseen Conditionscited by 68
- 2021Balanced-MixUp for Highly Imbalanced Medical Image Classificationcited by 46
- 2021CarveMix: A Simple Data Augmentation Method for Brain Lesion Segmentationcited by 30
- 2019Skin Lesion Synthesis with Generative Adversarial Networkscited by 22
- 2021A Structural Causal Model for MR Images of Multiple Sclerosiscited by 21
- 2020Pseudo-healthy synthesis with pathology disentanglement and adversarial learningcited by 19
- 2022InsMix: Towards Realistic Generative Data Augmentation for Nuclei Instance Segmentationcited by 19
- 2021Free-form tumor synthesis in computed tomography images via richer generative adversarial networkcited by 16
- 2018Learning Data Augmentation for Brain Tumor Segmentation with Coarse-to-Fine Generative Adversarial Networkscited by 15
5 more
- 2019Multiple Sclerosis Lesion Synthesis in MRI using an encoder-decoder U-NETcited by 13
- 2019Data Augmentation for Skin Lesion using Self-Attention based Progressive Generative Adversarial Networkcited by 13
- 2021ObjectAug: Object-level Data Augmentation for Semantic Image Segmentationcited by 11
- 2022Subject-Specific Lesion Generation and Pseudo-Healthy Synthesis for Multiple Sclerosis Brain Imagescited by 5
- 2022Adnexal Mass Segmentation with Ultrasound Data Synthesiscited by 2
Built on by
Citing papers per year: 2024: 5; 2025: 1; 2026: 1.
7 papers.
- 2024A Foundation Model for Brain Lesion Segmentation with Mixture of Modality Expertscited by 13
- 2024Analyzing Tumors by Synthesiscited by 11
- 2024Synthetic Data for Robust Stroke Segmentationcited by 4
- 2024SegHeD: Segmentation of Heterogeneous Data for Multiple Sclerosis Lesions with Anatomical Constraintscited by 3
- 2024SegHeD+: Segmentation of Heterogeneous Data for Multiple Sclerosis Lesions with Anatomical Constraints and Lesion-aware Augmentationcited by 1
- 2025HSMix: Hard and Soft Mixing Data Augmentation for Medical Image Segmentationcited by 0
- 2026MedDiffuseMix: Preserving Diagnostic Evidence with Saliency-Aware Diffusion Medical Image Data Augmentationcited by 0
- 2026MedDiffuseMix: Preserving Diagnostic Evidence with Saliency-Aware Diffusion Medical Image Data Augmentation25 Jun 2026
- 2025HSMix: Hard and Soft Mixing Data Augmentation for Medical Image Segmentation18 Nov 2025
- 2024SegHeD+: Segmentation of Heterogeneous Data for Multiple Sclerosis Lesions with Anatomical Constraints and Lesion-aware Augmentation14 Dec 2024
- 2024SegHeD: Segmentation of Heterogeneous Data for Multiple Sclerosis Lesions with Anatomical Constraints2 Oct 2024
- 2024Analyzing Tumors by Synthesis9 Sep 2024
- 2024A Foundation Model for Brain Lesion Segmentation with Mixture of Modality Experts16 May 2024
- 2024Synthetic Data for Robust Stroke Segmentation2 Apr 2024