A Survey of Multimodal Information Fusion for Smart Healthcare: Mapping the Journey from Data to Wisdom
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Abstract (arXiv)
Multimodal medical data fusion has emerged as a transformative approach in smart healthcare, enabling a comprehensive understanding of patient health and personalized treatment plans. In this paper, a journey from data to information to knowledge to wisdom (DIKW) is explored through multimodal fusion for smart healthcare. We present a comprehensive review of multimodal medical data fusion focused on the integration of various data modalities. The review explores different approaches such as feature selection, rule-based systems, machine learning, deep learning, and natural language processing, for fusing and analyzing multimodal data. This paper also highlights the challenges associated with multimodal fusion in healthcare. By synthesizing the reviewed frameworks and theories, it proposes a generic framework for multimodal medical data fusion that aligns with the DIKW model. Moreover, it discusses future directions related to the four pillars of healthcare: Predictive, Preventive, Personalized, and Participatory approaches. The components of the comprehensive survey presented in this paper form the foundation for more successful implementation of multimodal fusion in smart healthcare. Our findings can guide researchers and practitioners in leveraging the power of multimodal fusion with the state-of-the-art approaches to revolutionize healthcare and improve patient outcomes.
Key facts. Cited by 25 papers in the map (data through 14 Oct 2026). First posted on arXiv 21 Jun 2023.
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Citing papers per year: 2023: 1; 2024: 14; 2025: 8; 2026: 2.
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- 2024FuseMoE: Mixture-of-Experts Transformers for Fleximodal Fusioncited by 68
- 2024Review of multimodal machine learning approaches in healthcarecited by 31
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Surveycited by 20
- 2024MedAide: Information Fusion and Anatomy of Medical Intents via LLM-based Agent Collaborationcited by 16
- 2024Promoting cross-modal representations to improve multimodal foundation models for physiological signalscited by 13
- 2025CLIMB: Data Foundations for Large Scale Multimodal Clinical Foundation Modelscited by 13
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
- 2024DF-DM: A foundational process model for multimodal data fusion in the artificial intelligence eracited by 9
- 2025MoE-Health: A Mixture of Experts Framework for Robust Multimodal Healthcare Predictioncited by 7
- 2025Longitudinal Flow Matching for Trajectory Modelingcited by 7
- 2024Vital Insight: Assisting Experts' Context-Driven Sensemaking of Multi-modal Personal Tracking Data Using Visualization and Human-In-The-Loop LLMcited by 5
- 2023A Survey on Image-text Multimodal Modelscited by 4
13 more
- 2024Multimodal Deep Learning for Low-Resource Settings: A Vector Embedding Alignment Approach for Healthcare Applicationscited by 4
- 2025A Narrative Review on Large AI Models in Lung Cancer Screening, Diagnosis, and Treatment Planningcited by 4
- 2025Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 2025cited by 4
- 2024Federated and Transfer Learning for Cancer Detection Based on Image Analysiscited by 3
- 2025Equitable Electronic Health Record Prediction with FAME: Fairness-Aware Multimodal Embeddingcited by 2
- 2024TNF: Tri-branch Neural Fusion for Multimodal Medical Data Classificationcited by 1
- 2024Multi-modal Heart Failure Risk Estimation based on Short ECG and Sampled Long-Term HRVcited by 1
- 2024Lifestyle-Informed Personalized Blood Biomarker Prediction via Novel Representation Learningcited by 1
- 2024Exploring Multi-Modality Dynamics: Insights and Challenges in Multimodal Fusion for Biomedical Taskscited by 0
- 2025Challenges and proposed solutions in modeling multimodal medical data: A systematic reviewcited by 0
- 2025Enhanced Fracture Diagnosis Based on Critical Regional and Scale Aware in YOLOcited by 0
- 2026LENS-GRF: Permutation-Invariant Lesion Evidence Network with Gated Residual Fusion for Acne Severity Grading and Multi-Rater Clinical Oracle Analysiscited by 0
- 2026SpikeMoE: Brain-Inspired Competitive Routing for Flexible Spiking Mixture-of-Expertscited by 0
- 2026SpikeMoE: Brain-Inspired Competitive Routing for Flexible Spiking Mixture-of-Experts1 Oct 2026
- 2026LENS-GRF: Permutation-Invariant Lesion Evidence Network with Gated Residual Fusion for Acne Severity Grading and Multi-Rater Clinical Oracle Analysis25 Sep 2026
- 2025Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 202517 Oct 2025
- 2025Longitudinal Flow Matching for Trajectory Modeling3 Oct 2025
- 2025Enhanced Fracture Diagnosis Based on Critical Regional and Scale Aware in YOLO27 Sep 2025
- 2025MoE-Health: A Mixture of Experts Framework for Robust Multimodal Healthcare Prediction29 Aug 2025
- 2025Equitable Electronic Health Record Prediction with FAME: Fairness-Aware Multimodal Embedding16 Jun 2025
- 2025A Narrative Review on Large AI Models in Lung Cancer Screening, Diagnosis, and Treatment Planning8 Jun 2025
- 2025Challenges and proposed solutions in modeling multimodal medical data: A systematic review11 May 2025
- 2025CLIMB: Data Foundations for Large Scale Multimodal Clinical Foundation Models9 Mar 2025
- 2024Exploring Multi-Modality Dynamics: Insights and Challenges in Multimodal Fusion for Biomedical Tasks1 Nov 2024
- 2024Promoting cross-modal representations to improve multimodal foundation models for physiological signals21 Oct 2024
13 more
- 2024Vital Insight: Assisting Experts' Context-Driven Sensemaking of Multi-modal Personal Tracking Data Using Visualization and Human-In-The-Loop LLM18 Oct 2024
- 2024MedAide: Information Fusion and Anatomy of Medical Intents via LLM-based Agent Collaboration16 Oct 2024
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey23 Aug 2024
- 2024Lifestyle-Informed Personalized Blood Biomarker Prediction via Novel Representation Learning9 Jul 2024
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directions28 Jun 2024
- 2024Multimodal Deep Learning for Low-Resource Settings: A Vector Embedding Alignment Approach for Healthcare Applications2 Jun 2024
- 2024Federated and Transfer Learning for Cancer Detection Based on Image Analysis30 May 2024
- 2024DF-DM: A foundational process model for multimodal data fusion in the artificial intelligence era18 Apr 2024
- 2024TNF: Tri-branch Neural Fusion for Multimodal Medical Data Classification4 Mar 2024
- 2024Multi-modal Heart Failure Risk Estimation based on Short ECG and Sampled Long-Term HRV1 Mar 2024
- 2024FuseMoE: Mixture-of-Experts Transformers for Fleximodal Fusion5 Feb 2024
- 2024Review of multimodal machine learning approaches in healthcare4 Feb 2024
- 2023A Survey on Image-text Multimodal Models23 Sep 2023
- 2025Longitudinal Flow Matching for Trajectory Modelingcited by 7
- 2025Longitudinal Flow Matching for Trajectory Modeling3 Oct 2025
- 2024Review of multimodal machine learning approaches in healthcarecited by 31
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Surveycited by 20
- 2024Promoting cross-modal representations to improve multimodal foundation models for physiological signalscited by 13
- 2025CLIMB: Data Foundations for Large Scale Multimodal Clinical Foundation Modelscited by 13
- 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
- 2024DF-DM: A foundational process model for multimodal data fusion in the artificial intelligence eracited by 9
- 2024Vital Insight: Assisting Experts' Context-Driven Sensemaking of Multi-modal Personal Tracking Data Using Visualization and Human-In-The-Loop LLMcited by 5
- 2023A Survey on Image-text Multimodal Modelscited by 4
- 2024Multimodal Deep Learning for Low-Resource Settings: A Vector Embedding Alignment Approach for Healthcare Applicationscited by 4
- 2025A Narrative Review on Large AI Models in Lung Cancer Screening, Diagnosis, and Treatment Planningcited by 4
- 2025Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 2025cited by 4
- 2024Federated and Transfer Learning for Cancer Detection Based on Image Analysiscited by 3
12 most cited of 20 All 20 (JSON)
- 2026LENS-GRF: Permutation-Invariant Lesion Evidence Network with Gated Residual Fusion for Acne Severity Grading and Multi-Rater Clinical Oracle Analysis25 Sep 2026
- 2025Reflections from Research Roundtables at the Conference on Health, Inference, and Learning (CHIL) 202517 Oct 2025
- 2025Enhanced Fracture Diagnosis Based on Critical Regional and Scale Aware in YOLO27 Sep 2025
- 2025Equitable Electronic Health Record Prediction with FAME: Fairness-Aware Multimodal Embedding16 Jun 2025
- 2025A Narrative Review on Large AI Models in Lung Cancer Screening, Diagnosis, and Treatment Planning8 Jun 2025
- 2025Challenges and proposed solutions in modeling multimodal medical data: A systematic review11 May 2025
- 2025CLIMB: Data Foundations for Large Scale Multimodal Clinical Foundation Models9 Mar 2025
- 2024Exploring Multi-Modality Dynamics: Insights and Challenges in Multimodal Fusion for Biomedical Tasks1 Nov 2024
- 2024Promoting cross-modal representations to improve multimodal foundation models for physiological signals21 Oct 2024
- 2024Vital Insight: Assisting Experts' Context-Driven Sensemaking of Multi-modal Personal Tracking Data Using Visualization and Human-In-The-Loop LLM18 Oct 2024
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey23 Aug 2024
- 2024Lifestyle-Informed Personalized Blood Biomarker Prediction via Novel Representation Learning9 Jul 2024
12 newest of 20 All 20 (JSON)