Mixture of Experts for Biomedical Question Answering
On the map: Mixture-of-experts → Medical and biomedical MoE
Abstract (arXiv)
Biomedical Question Answering (BQA) has attracted increasing attention in recent years due to its promising application prospect. It is a challenging task because the biomedical questions are professional and usually vary widely. Existing question answering methods answer all questions with a homogeneous model, leading to various types of questions competing for the shared parameters, which will confuse the model decision for each single type of questions. In this paper, in order to alleviate the parameter competition problem, we propose a Mixture-of-Expert (MoE) based question answering method called MoEBQA that decouples the computation for different types of questions by sparse routing. To be specific, we split a pretrained Transformer model into bottom and top blocks. The bottom blocks are shared by all the examples, aiming to capture the general features. The top blocks are extended to an MoE version that consists of a series of independent experts, where each example is assigned to a few experts according to its underlying question type. MoEBQA automatically learns the routing strategy in an end-to-end manner so that each expert tends to deal with the question types it is expert in. We evaluate MoEBQA on three BQA datasets constructed based on real examinations. The results show that our MoE extension significantly boosts the performance of question answering models and achieves new state-of-the-art performance. In addition, we elaborately analyze our MoE modules to reveal how MoEBQA works and find that it can automatically group the questions into human-readable clusters.
Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Placed in Medical and biomedical MoE, one of 12 directions in Mixture-of-experts. Builds on 20 of its 24 references that are in the map. First posted on arXiv 15 Apr 2022.
Builds on
20 of 24 references.
References · 20
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8 more
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Built on by
Citing papers per year: 2023: 2; 2024: 3; 2025: 1.
6 papers.
- 2023Enhancing Small Medical Learners with Privacy-preserving Contextual Promptingcited by 11
- 2024DESIRE-ME: Domain-Enhanced Supervised Information REtrieval using Mixture-of-Expertscited by 7
- 2023CAME: Competitively Learning a Mixture-of-Experts Model for First-stage Retrievalcited by 6
- 2024Investigating Mixture of Experts in Dense Retrievalcited by 4
- 2025Mixture of Experts Approaches in Dense Retrieval Taskscited by 2
- 2024M2oE: Multimodal Collaborative Expert Peptide Modelcited by 0
- 2025Mixture of Experts Approaches in Dense Retrieval Tasks17 Oct 2025
- 2024Investigating Mixture of Experts in Dense Retrieval16 Dec 2024
- 2024M2oE: Multimodal Collaborative Expert Peptide Model20 Nov 2024
- 2024DESIRE-ME: Domain-Enhanced Supervised Information REtrieval using Mixture-of-Experts20 Mar 2024
- 2023CAME: Competitively Learning a Mixture-of-Experts Model for First-stage Retrieval6 Nov 2023
- 2023Enhancing Small Medical Learners with Privacy-preserving Contextual Prompting22 May 2023
Similar, not cited
Close in wording, no citation either way
- 2022Build a Robust QA System with Transformer-based Mixture of Experts
- 2025RAG-BioQA: A Retrieval-Augmented Generation Framework for Long-Form Biomedical Question Answering
- 2025Harnessing Collective Intelligence of LLMs for Robust Biomedical QA: A Multi-Model Approach
- 2026UETQuintet at BioCreative IX -- MedHopQA: Enhancing Biomedical QA with Selective Multi-hop Reasoning and Contextual Retrieval
- 2026Overview of the MedHopQA track at BioCreative IX: track description, participation and evaluation of systems for multi-hop medical question answering
- 2026From Voting to Agent Collaboration: Answer-Type-Aware LLM Pipelines for BioASQ 14b
- 2026MambaFormer: Token-Level Guided Routing Mixture-of-Experts for Accurate and Efficient Clinical Assistance
- 2026Adaptive Retrieval Strategies for Biomedical Question Answering