mlsanityData to 7 Oct 2026

Mixture of Experts for Biomedical Question Answering

arXiv 2204.07469 ↗First posted 15 Apr 2022cs.CLcited by 6

On the map: Mixture-of-experts → Medical and biomedical MoE

Abstract (arXiv)

Biomedical Question Answering (BQA) has attracted increasing attention in recent years due to its promising application prospect. It is a challenging task because the biomedical questions are professional and usually vary widely. Existing question answering methods answer all questions with a homogeneous model, leading to various types of questions competing for the shared parameters, which will confuse the model decision for each single type of questions. In this paper, in order to alleviate the parameter competition problem, we propose a Mixture-of-Expert (MoE) based question answering method called MoEBQA that decouples the computation for different types of questions by sparse routing. To be specific, we split a pretrained Transformer model into bottom and top blocks. The bottom blocks are shared by all the examples, aiming to capture the general features. The top blocks are extended to an MoE version that consists of a series of independent experts, where each example is assigned to a few experts according to its underlying question type. MoEBQA automatically learns the routing strategy in an end-to-end manner so that each expert tends to deal with the question types it is expert in. We evaluate MoEBQA on three BQA datasets constructed based on real examinations. The results show that our MoE extension significantly boosts the performance of question answering models and achieves new state-of-the-art performance. In addition, we elaborately analyze our MoE modules to reveal how MoEBQA works and find that it can automatically group the questions into human-readable clusters.

Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Placed in Medical and biomedical MoE, one of 12 directions in Mixture-of-experts. Builds on 20 of its 24 references that are in the map. First posted on arXiv 15 Apr 2022.

Builds on

20 of 24 references.

References · 20

  1. 2018BERT: Pre-training of Deep Bidirectional Transformers for Language Understandingcited by 40,204
  2. 2019RoBERTa: A Robustly Optimized BERT Pretraining Approachcited by 13,266
  3. 2017Outrageously Large Neural Networks: The Sparsely-Gated Mixture-of-Experts Layercited by 3,413
  4. 2021Switch Transformers: Scaling to Trillion Parameter Models with Simple and Efficient Sparsitycited by 3,014
  5. 2019BioBERT: a pre-trained biomedical language representation model for biomedical text miningcited by 1,935
  6. 2017Decoupled Weight Decay Regularizationcited by 1,722
  7. 2020GShard: Scaling Giant Models with Conditional Computation and Automatic Shardingcited by 1,601
  8. 2020Don't Stop Pretraining: Adapt Language Models to Domains and Taskscited by 1,548
  9. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
  10. 2020Domain-Specific Language Model Pretraining for Biomedical Natural Language Processingcited by 996
  11. 2019Publicly Available Clinical BERT Embeddingscited by 995
  12. 2017Reading Wikipedia to Answer Open-Domain Questionscited by 777
8 more
  1. 2021BASE Layers: Simplifying Training of Large, Sparse Modelscited by 315
  2. 2019ERNIE: Enhanced Representation through Knowledge Integrationcited by 301
  3. 2016Bidirectional Attention Flow for Machine Comprehensioncited by 278
  4. 2021Hash Layers For Large Sparse Modelscited by 236
  5. 2018emrQA: A Large Corpus for Question Answering on Electronic Medical Recordscited by 134
  6. 2019HEAD-QA: A Healthcare Dataset for Complex Reasoningcited by 100
  7. 2021Mixture-of-Partitions: Infusing Large Biomedical Knowledge Graphs into BERTcited by 14
  8. 2020Interpretable Multi-Step Reasoning with Knowledge Extraction on Complex Healthcare Question Answeringcited by 7

Built on by

Cited by year

Citing papers per year: 2023: 2; 2024: 3; 2025: 1.

6 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2022Build a Robust QA System with Transformer-based Mixture of Experts
  2. 2025RAG-BioQA: A Retrieval-Augmented Generation Framework for Long-Form Biomedical Question Answering
  3. 2025Harnessing Collective Intelligence of LLMs for Robust Biomedical QA: A Multi-Model Approach
  4. 2026UETQuintet at BioCreative IX -- MedHopQA: Enhancing Biomedical QA with Selective Multi-hop Reasoning and Contextual Retrieval
  5. 2026Overview of the MedHopQA track at BioCreative IX: track description, participation and evaluation of systems for multi-hop medical question answering
  6. 2026From Voting to Agent Collaboration: Answer-Type-Aware LLM Pipelines for BioASQ 14b
  7. 2026MambaFormer: Token-Level Guided Routing Mixture-of-Experts for Accurate and Efficient Clinical Assistance
  8. 2026Adaptive Retrieval Strategies for Biomedical Question Answering