Mixed Transformer U-Net For Medical Image Segmentation
Not on the map. Why?
Abstract (arXiv)
Though U-Net has achieved tremendous success in medical image segmentation tasks, it lacks the ability to explicitly model long-range dependencies. Therefore, Vision Transformers have emerged as alternative segmentation structures recently, for their innate ability of capturing long-range correlations through Self-Attention (SA). However, Transformers usually rely on large-scale pre-training and have high computational complexity. Furthermore, SA can only model self-affinities within a single sample, ignoring the potential correlations of the overall dataset. To address these problems, we propose a novel Transformer module named Mixed Transformer Module (MTM) for simultaneous inter- and intra- affinities learning. MTM first calculates self-affinities efficiently through our well-designed Local-Global Gaussian-Weighted Self-Attention (LGG-SA). Then, it mines inter-connections between data samples through External Attention (EA). By using MTM, we construct a U-shaped model named Mixed Transformer U-Net (MT-UNet) for accurate medical image segmentation. We test our method on two different public datasets, and the experimental results show that the proposed method achieves better performance over other state-of-the-art methods. The code is available at: https://github.com/Dootmaan/MT-UNet.
Key facts. Cited by 95 papers in the map (data through 7 Oct 2026). Builds on 19 of its 21 references that are in the map. First posted on arXiv 8 Nov 2021.
Builds on
19 of 21 references.
References · 19
- 2017Attention Is All You Needcited by 59,932
- 2014Adam: A Method for Stochastic Optimizationcited by 36,960
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2020End-to-End Object Detection with Transformerscited by 7,384
- 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
- 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
- 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
- 2019Axial Attention in Multidimensional Transformerscited by 350
- 2020UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentationcited by 331
- 2018Attention Gated Networks: Learning to Leverage Salient Regions in Medical Imagescited by 271
7 more
- 2021TransBTS: Multimodal Brain Tumor Segmentation Using Transformercited by 265
- 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
- 2019Pay Less Attention with Lightweight and Dynamic Convolutionscited by 211
- 2021Beyond Self-attention: External Attention using Two Linear Layers for Visual Taskscited by 109
- 2019TENER: Adapting Transformer Encoder for Named Entity Recognitioncited by 69
- 2020Domain Adaptive Relational Reasoning for 3D Multi-Organ Segmentationcited by 48
- 2021TransClaw U-Net: Claw U-Net with Transformers for Medical Image Segmentationcited by 41
Built on by
Citing papers per year: 2022: 18; 2023: 19; 2024: 28; 2025: 22; 2026: 8.
95 papers.
Sort:
By area:
- 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentationcited by 286
- 2022Medical Image Segmentation Review: The success of U-Netcited by 190
- 2024EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentationcited by 64
- 2022Transformers in Medical Image Analysis: A Reviewcited by 41
- 2023Multi-scale Hierarchical Vision Transformer with Cascaded Attention Decoding for Medical Image Segmentationcited by 34
- 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
- 2022The Fully Convolutional Transformer for Medical Image Segmentationcited by 31
- 2023Ladder Fine-tuning approach for SAM integrating complementary networkcited by 25
- 2022Transformer Meets Boundary Value Inverse Problemscited by 22
- 2023G-CASCADE: Efficient Cascaded Graph Convolutional Decoding for 2D Medical Image Segmentationcited by 21
- 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
- 2022BATFormer: Towards Boundary-Aware Lightweight Transformer for Efficient Medical Image Segmentationcited by 14
38 more
- 2022Optimizing Vision Transformers for Medical Image Segmentationcited by 12
- 2023MIST: Medical Image Segmentation Transformer with Convolutional Attention Mixing (CAM) Decodercited by 12
- 2024CSWin-UNet: Transformer UNet with Cross-Shaped Windows for Medical Image Segmentationcited by 12
- 2024MetaSeg: MetaFormer-based Global Contexts-aware Network for Efficient Semantic Segmentationcited by 12
- 2024SliceMamba with Neural Architecture Search for Medical Image Segmentationcited by 11
- 2022The Lighter The Better: Rethinking Transformers in Medical Image Segmentation Through Adaptive Pruningcited by 9
- 2022Recent Progress in Transformer-based Medical Image Analysiscited by 9
- 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
- 2024D-Net: Dynamic Large Kernel with Dynamic Feature Fusion for Volumetric Medical Image Segmentationcited by 9
- 2025Vision Foundation Models in Medical Image Analysis: Advances and Challengescited by 9
- 2022MEW-UNet: Multi-axis representation learning in frequency domain for medical image segmentationcited by 8
- 2024PSFHS Challenge Report: Pubic Symphysis and Fetal Head Segmentation from Intrapartum Ultrasound Imagescited by 8
- 2022BirdSoundsDenoising: Deep Visual Audio Denoising for Bird Soundscited by 7
- 2025RWKV-UNet: Improving UNet with Long-Range Cooperation for Effective Medical Image Segmentationcited by 7
- 2022UNet-2022: Exploring Dynamics in Non-isomorphic Architecturecited by 6
- 2024A Comparative Survey of Vision Transformers for Feature Extraction in Texture Analysiscited by 6
- 2024CNN-Transformer Rectified Collaborative Learning for Medical Image Segmentationcited by 6
- 2024LV-UNet: A Lightweight and Vanilla Model for Medical Image Segmentationcited by 6
- 2025SRMamba: Mamba for Super-Resolution of LiDAR Point Cloudscited by 5
- 2025CENet: Context Enhancement Network for Medical Image Segmentationcited by 5
- 2022Annotation by Clicks: A Point-Supervised Contrastive Variance Method for Medical Semantic Segmentationcited by 4
- 2022Valuing Vicinity: Memory attention framework for context-based semantic segmentation in histopathologycited by 3
- 2023Towards more precise automatic analysis: a comprehensive survey of deep learning-based multi-organ segmentationcited by 3
- 2023Multiscale Progressive Text Prompt Network for Medical Image Segmentationcited by 3
- 2023Medical Image Segmentation via Sparse Coding Decodercited by 3
- 2023Complex Image Generation SwinTransformer Network for Audio Denoisingcited by 3
- 2023Learning Multi-axis Representation in Frequency Domain for Medical Image Segmentationcited by 3
- 2024Deep models for stroke segmentation: do complex architectures always perform better?cited by 3
- 2024AgileFormer: Spatially Agile Transformer UNet for Medical Image Segmentationcited by 3
- 2024Rethinking Attention Gated with Hybrid Dual Pyramid Transformer-CNN for Generalized Segmentation in Medical Imagingcited by 3
- 2024Are Vision xLSTM Embedded UNet More Reliable in Medical 3D Image Segmentation?cited by 3
- 2025Merging Context Clustering with Visual State Space Models for Medical Image Segmentationcited by 3
- 2025OSDMamba: Enhancing Oil Spill Detection from Remote Sensing Images Using Selective State Space Modelcited by 3
- 2025UltraLBM-UNet: Ultralight Bidirectional Mamba-based Model for Skin Lesion Segmentationcited by 3
- 2022Exemplar Learning for Medical Image Segmentationcited by 2
- 2023Self-pruning Graph Neural Network for Predicting Inflammatory Disease Activity in Multiple Sclerosis from Brain MR Imagescited by 2
- 2023DPATD: Dual-Phase Audio Transformer for Denoisingcited by 2
- 2023AI-SAM: Automatic and Interactive Segment Anything Modelcited by 2
50 most cited of 95 All 95 (JSON)
- 2026Federated Multi-Task Learning for Bladder Tumor Segmentation and MIBC Classification Using a Hybrid CNN-Transformer Architecture31 Aug 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026MAE-Based Self-Supervised Pretraining for Data-Efficient Medical Image Segmentation Using nnFormer22 Apr 2026
- 2026MedFlowSeg: Flow Matching for Medical Image Segmentation with Frequency-Aware Attention21 Apr 2026
- 2026XAttnRes: Cross-Stage Attention Residuals for Medical Image Segmentation28 Mar 2026
- 2026Decoding Matters: Efficient Mamba-Based Decoder with Distribution-Aware Deep Supervision for Medical Image Segmentation13 Mar 2026
- 2026Gated Differential Linear Attention: A Linear-Time Decoder for High-Fidelity Medical Segmentation3 Mar 2026
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentation27 Jan 2026
- 2025GCA-ResUNet: Medical Image Segmentation Using Grouped Coordinate Attention30 Dec 2025
- 2025UltraLBM-UNet: Ultralight Bidirectional Mamba-based Model for Skin Lesion Segmentation25 Dec 2025
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentation20 Dec 2025
- 2025Layer-wise Noise Guided Selective Wavelet Reconstruction for Robust Medical Image Segmentation20 Nov 2025
38 more
- 2025MACMD: Multi-dilated Contextual Attention and Channel Mixer Decoding for Medical Image Segmentation8 Nov 2025
- 2025RDTE-UNet: A Boundary and Detail Aware UNet for Precise Medical Image Segmentation3 Nov 2025
- 2025SPG-CDENet: Spatial Prior-Guided Cross Dual Encoder Network for Multi-Organ Segmentation30 Oct 2025
- 2025LoMix: Learnable Weighted Multi-Scale Logits Mixing for Medical Image Segmentation27 Oct 2025
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentation4 Oct 2025
- 2025Dual Interaction Network with Cross-Image Attention for Medical Image Segmentation7 Sep 2025
- 2025MSA2-Net: Utilizing Self-Adaptive Convolution Module to Extract Multi-Scale Information in Medical Image Segmentation1 Sep 2025
- 2025Enhanced Liver Tumor Detection in CT Images Using 3D U-Net and Bat Algorithm for Hyperparameter Optimization11 Aug 2025
- 2025TCSAFormer: Efficient Vision Transformer with Token Compression and Sparse Attention for Medical Image Segmentation6 Aug 2025
- 2025Similarity Memory Prior is All You Need for Medical Image Segmentation1 Jul 2025
- 2025OSDMamba: Enhancing Oil Spill Detection from Remote Sensing Images Using Selective State Space Model22 Jun 2025
- 2025CENet: Context Enhancement Network for Medical Image Segmentation23 May 2025
- 2025SRMamba: Mamba for Super-Resolution of LiDAR Point Clouds15 May 2025
- 2025A Neural Network Architecture Based on Attention Gate Mechanism for 3D Magnetotelluric Forward Modeling14 Mar 2025
- 2025Vision Foundation Models in Medical Image Analysis: Advances and Challenges20 Feb 2025
- 2025RWKV-UNet: Improving UNet with Long-Range Cooperation for Effective Medical Image Segmentation14 Jan 2025
- 2025GLoG-CSUnet: Enhancing Vision Transformers with Adaptable Radiomic Features for Medical Image Segmentation6 Jan 2025
- 2025Merging Context Clustering with Visual State Space Models for Medical Image Segmentation3 Jan 2025
- 2024Y-CA-Net: A Convolutional Attention Based Network for Volumetric Medical Image Segmentation1 Oct 2024
- 2024Toward Deep Learning-based Segmentation and Quantitative Analysis of Cervical Spinal Cord Magnetic Resonance Images28 Sep 2024
- 2024PSFHS Challenge Report: Pubic Symphysis and Fetal Head Segmentation from Intrapartum Ultrasound Images17 Sep 2024
- 2024TransDAE: Dual Attention Mechanism in a Hierarchical Transformer for Efficient Medical Image Segmentation3 Sep 2024
- 2024LV-UNet: A Lightweight and Vanilla Model for Medical Image Segmentation29 Aug 2024
- 2024CNN-Transformer Rectified Collaborative Learning for Medical Image Segmentation25 Aug 2024
- 2024MetaSeg: MetaFormer-based Global Contexts-aware Network for Efficient Semantic Segmentation14 Aug 2024
- 2024CSWin-UNet: Transformer UNet with Cross-Shaped Windows for Medical Image Segmentation25 Jul 2024
- 2024SACNet: A Spatially Adaptive Convolution Network for 2D Multi-organ Medical Segmentation14 Jul 2024
- 2024SliceMamba with Neural Architecture Search for Medical Image Segmentation11 Jul 2024
- 2024Are Vision xLSTM Embedded UNet More Reliable in Medical 3D Image Segmentation?24 Jun 2024
- 2024Complex Image-Generative Diffusion Transformer for Audio Denoising13 Jun 2024
- 2024Diffusion Gaussian Mixture Audio Denoise13 Jun 2024
- 2024A Comparative Survey of Vision Transformers for Feature Extraction in Texture Analysis10 Jun 2024
- 2024EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentation11 May 2024
- 2024D-TrAttUnet: Toward Hybrid CNN-Transformer Architecture for Generic and Subtle Segmentation in Medical Images7 May 2024
- 2024Rethinking Attention Gated with Hybrid Dual Pyramid Transformer-CNN for Generalized Segmentation in Medical Imaging28 Apr 2024
- 2024Cross-model Mutual Learning for Exemplar-based Medical Image Segmentation18 Apr 2024
- 2024AKGNet: Attribute Knowledge-Guided Unsupervised Lung-Infected Area Segmentation17 Apr 2024
- 2024Q2A: Querying Implicit Fully Continuous Feature Pyramid to Align Features for Medical Image Segmentation15 Apr 2024
50 newest of 95 All 95 (JSON)
- 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentationcited by 286
- 2024SliceMamba with Neural Architecture Search for Medical Image Segmentationcited by 11
- 2025SRMamba: Mamba for Super-Resolution of LiDAR Point Cloudscited by 5
- 2025OSDMamba: Enhancing Oil Spill Detection from Remote Sensing Images Using Selective State Space Modelcited by 3
- 2025UltraLBM-UNet: Ultralight Bidirectional Mamba-based Model for Skin Lesion Segmentationcited by 3
- 2024Attention-Mamba: A Mamba-Enhanced Multi-Scale Parallel Inference Network for Medical Image Segmentationcited by 0
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentationcited by 0
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentationcited by 0
- 2026Decoding Matters: Efficient Mamba-Based Decoder with Distribution-Aware Deep Supervision for Medical Image Segmentationcited by 0
- 2026Decoding Matters: Efficient Mamba-Based Decoder with Distribution-Aware Deep Supervision for Medical Image Segmentation13 Mar 2026
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentation27 Jan 2026
- 2025UltraLBM-UNet: Ultralight Bidirectional Mamba-based Model for Skin Lesion Segmentation25 Dec 2025
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentation4 Oct 2025
- 2025OSDMamba: Enhancing Oil Spill Detection from Remote Sensing Images Using Selective State Space Model22 Jun 2025
- 2025SRMamba: Mamba for Super-Resolution of LiDAR Point Clouds15 May 2025
- 2024SliceMamba with Neural Architecture Search for Medical Image Segmentation11 Jul 2024
- 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentation4 Feb 2024
- 2024Attention-Mamba: A Mamba-Enhanced Multi-Scale Parallel Inference Network for Medical Image Segmentation3 Feb 2024
- 2022Medical Image Segmentation Review: The success of U-Netcited by 190
- 2024EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentationcited by 64
- 2022Transformers in Medical Image Analysis: A Reviewcited by 41
- 2023Multi-scale Hierarchical Vision Transformer with Cascaded Attention Decoding for Medical Image Segmentationcited by 34
- 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
- 2022The Fully Convolutional Transformer for Medical Image Segmentationcited by 31
- 2023Ladder Fine-tuning approach for SAM integrating complementary networkcited by 25
- 2022Transformer Meets Boundary Value Inverse Problemscited by 22
- 2023G-CASCADE: Efficient Cascaded Graph Convolutional Decoding for 2D Medical Image Segmentationcited by 21
- 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
- 2022BATFormer: Towards Boundary-Aware Lightweight Transformer for Efficient Medical Image Segmentationcited by 14
- 2022Optimizing Vision Transformers for Medical Image Segmentationcited by 12
12 most cited of 83 All 83 (JSON)
- 2026Federated Multi-Task Learning for Bladder Tumor Segmentation and MIBC Classification Using a Hybrid CNN-Transformer Architecture31 Aug 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026MAE-Based Self-Supervised Pretraining for Data-Efficient Medical Image Segmentation Using nnFormer22 Apr 2026
- 2026XAttnRes: Cross-Stage Attention Residuals for Medical Image Segmentation28 Mar 2026
- 2026Gated Differential Linear Attention: A Linear-Time Decoder for High-Fidelity Medical Segmentation3 Mar 2026
- 2025GCA-ResUNet: Medical Image Segmentation Using Grouped Coordinate Attention30 Dec 2025
- 2025Atlas is Your Perfect Context: One-Shot Customization for Generalizable Foundational Medical Image Segmentation20 Dec 2025
- 2025Layer-wise Noise Guided Selective Wavelet Reconstruction for Robust Medical Image Segmentation20 Nov 2025
- 2025MACMD: Multi-dilated Contextual Attention and Channel Mixer Decoding for Medical Image Segmentation8 Nov 2025
- 2025RDTE-UNet: A Boundary and Detail Aware UNet for Precise Medical Image Segmentation3 Nov 2025
- 2025SPG-CDENet: Spatial Prior-Guided Cross Dual Encoder Network for Multi-Organ Segmentation30 Oct 2025
- 2025LoMix: Learnable Weighted Multi-Scale Logits Mixing for Medical Image Segmentation27 Oct 2025
12 newest of 83 All 83 (JSON)