A methodology for training homomorphicencryption friendly neural networks
Not on the map. Why?
Abstract (arXiv)
Privacy-preserving deep neural network (DNN) inference is a necessity in different regulated industries such as healthcare, finance and retail. Recently, homomorphic encryption (HE) has been used as a method to enable analytics while addressing privacy concerns. HE enables secure predictions over encrypted data. However, there are several challenges related to the use of HE, including DNN size limitations and the lack of support for some operation types. Most notably, the commonly used ReLU activation is not supported under some HE schemes. We propose a structured methodology to replace ReLU with a quadratic polynomial activation. To address the accuracy degradation issue, we use a pre-trained model that trains another HE-friendly model, using techniques such as trainable activation functions and knowledge distillation. We demonstrate our methodology on the AlexNet architecture, using the chest X-Ray and CT datasets for COVID-19 detection. Experiments using our approach reduced the gap between the F1 score and accuracy of the models trained with ReLU and the HE-friendly model to within a mere 0.32-5.3 percent degradation. We also demonstrate our methodology using the SqueezeNet architecture, for which we observed 7 percent accuracy and F1 improvements over training similar networks with other HE-friendly training methods.
Key facts. Cited by 10 papers in the map (data through 7 Oct 2026). Builds on 16 of its 49 references that are in the map. First posted on arXiv 5 Nov 2021.
Builds on
16 of 49 references.
References · 16
- 2015Distilling the Knowledge in a Neural Networkcited by 10,076
- 2020Knowledge Distillation: A Surveycited by 1,578
- 2016SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and <0.5MB model sizecited by 1,054
- 2019Improved Knowledge Distillation via Teacher Assistantcited by 567
- 2020COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Imagescited by 264
- 2020Can AI help in screening Viral and COVID-19 pneumonia?cited by 200
- 2020COVID-19 Image Data Collection: Prospective Predictions Are the Futurecited by 100
- 2021Privacy-Preserving Machine Learning with Fully Homomorphic Encryption for Deep Neural Networkcited by 57
- 2017CryptoDL: Deep Neural Networks over Encrypted Datacited by 56
- 2020COVIDNet-CT: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest CT Imagescited by 39
- 2019Glyph: Fast and Accurately Training Deep Neural Networks on Encrypted Datacited by 28
- 2020HeLayers: A Tile Tensors Framework for Large Neural Networks on Encrypted Datacited by 22
4 more
- 2019nGraph-HE2: A High-Throughput Framework for Neural Network Inference on Encrypted Datacited by 21
- 2016Learning activation functions from data using cubic spline interpolationcited by 13
- 2021Enabling Homomorphically Encrypted Inference for Large DNN Modelscited by 6
- 2019Privacy preserving Neural Network Inference on Encrypted Data with GPUscited by 4
Built on by
Citing papers per year: 2022: 1; 2023: 3; 2024: 1; 2025: 4; 2026: 1.
10 papers.
- 2023Converting Transformers to Polynomial Form for Secure Inference Over Homomorphic Encryptioncited by 19
- 2024Power-Softmax: Towards Secure LLM Inference over Encrypted Datacited by 6
- 2023Training Large Scale Polynomial CNNs for E2E Inference over Homomorphic Encryptioncited by 5
- 2023Privacy-preserving machine learning for healthcare: open challenges and future perspectivescited by 4
- 2022Efficient Pruning for Machine Learning Under Homomorphic Encryptioncited by 2
- 2025MIND: Modality-Informed Knowledge Distillation Framework for Multimodal Clinical Prediction Taskscited by 2
- 2025A Training Framework for Optimal and Stable Training of Polynomial Neural Networkscited by 2
- 2025Efficient Decoding Methods for Language Models on Encrypted Datacited by 2
- 2025Peregrine: One-Shot Fine-Tuning for FHE Inference of General Deep CNNscited by 1
- 2026Homomorphic Advantage Operator: Stabilizing Reinforcement Learning Under Fully Homomorphic Encryption Constraintscited by 0
- 2026Homomorphic Advantage Operator: Stabilizing Reinforcement Learning Under Fully Homomorphic Encryption Constraints1 Oct 2026
- 2025Peregrine: One-Shot Fine-Tuning for FHE Inference of General Deep CNNs24 Nov 2025
- 2025Efficient Decoding Methods for Language Models on Encrypted Data10 Sep 2025
- 2025A Training Framework for Optimal and Stable Training of Polynomial Neural Networks16 May 2025
- 2025MIND: Modality-Informed Knowledge Distillation Framework for Multimodal Clinical Prediction Tasks3 Feb 2025
- 2024Power-Softmax: Towards Secure LLM Inference over Encrypted Data12 Oct 2024
- 2023Converting Transformers to Polynomial Form for Secure Inference Over Homomorphic Encryption15 Nov 2023
- 2023Training Large Scale Polynomial CNNs for E2E Inference over Homomorphic Encryption26 Apr 2023
- 2023Privacy-preserving machine learning for healthcare: open challenges and future perspectives27 Mar 2023
- 2022Efficient Pruning for Machine Learning Under Homomorphic Encryption7 Jul 2022