Biomedical and Clinical Language Models for Spanish: On the Benefits of Domain-Specific Pretraining in a Mid-Resource Scenario
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Abstract (arXiv)
This work presents biomedical and clinical language models for Spanish by experimenting with different pretraining choices, such as masking at word and subword level, varying the vocabulary size and testing with domain data, looking for better language representations. Interestingly, in the absence of enough clinical data to train a model from scratch, we applied mixed-domain pretraining and cross-domain transfer approaches to generate a performant bio-clinical model suitable for real-world clinical data. We evaluated our models on Named Entity Recognition (NER) tasks for biomedical documents and challenging hospital discharge reports. When compared against the competitive mBERT and BETO models, we outperform them in all NER tasks by a significant margin. Finally, we studied the impact of the model's vocabulary on the NER performances by offering an interesting vocabulary-centric analysis. The results confirm that domain-specific pretraining is fundamental to achieving higher performances in downstream NER tasks, even within a mid-resource scenario. To the best of our knowledge, we provide the first biomedical and clinical transformer-based pretrained language models for Spanish, intending to boost native Spanish NLP applications in biomedicine. Our best models are freely available in the HuggingFace hub: https://huggingface.co/BSC-TeMU.
Key facts. Cited by 11 papers in the map (data through 7 Oct 2026). Builds on 14 of its 34 references that are in the map. First posted on arXiv 8 Sep 2021.
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References · 14
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Citing papers per year: 2022: 2; 2023: 4; 2024: 3; 2025: 0; 2026: 2.
11 papers.
- 2023DrBERT: A Robust Pre-trained Model in French for Biomedical and Clinical domainscited by 27
- 2024A Survey of Pre-trained Language Models for Processing Scientific Textcited by 7
- 2022RigoBERTa: A State-of-the-Art Language Model For Spanishcited by 5
- 2023EriBERTa: A Bilingual Pre-Trained Language Model for Clinical Natural Language Processingcited by 3
- 2024ClinLinker: Medical Entity Linking of Clinical Concept Mentions in Spanishcited by 3
- 2022Cross-Lingual Knowledge Transfer for Clinical Phenotypingcited by 2
- 2024Adaptation of Biomedical and Clinical Pretrained Models to French Long Documents: A Comparative Studycited by 2
- 2023UMLS-KGI-BERT: Data-Centric Knowledge Integration in Transformers for Biomedical Entity Recognitioncited by 1
- 2023Knowledge Graph Embeddings for Multi-Lingual Structured Representations of Radiology Reportscited by 1
- 2026Team Fusion@ SU@ BC8 SympTEMIST track: transformer-based approach for symptom recognition and linkingcited by 0
- 2026Automated ICD Classification of Psychiatric Diagnoses: From Classical NLP to Large Language Modelscited by 0
- 2026Automated ICD Classification of Psychiatric Diagnoses: From Classical NLP to Large Language Models20 May 2026
- 2026Team Fusion@ SU@ BC8 SympTEMIST track: transformer-based approach for symptom recognition and linking7 Apr 2026
- 2024ClinLinker: Medical Entity Linking of Clinical Concept Mentions in Spanish9 Apr 2024
- 2024Adaptation of Biomedical and Clinical Pretrained Models to French Long Documents: A Comparative Study26 Feb 2024
- 2024A Survey of Pre-trained Language Models for Processing Scientific Text31 Jan 2024
- 2023Knowledge Graph Embeddings for Multi-Lingual Structured Representations of Radiology Reports2 Sep 2023
- 2023UMLS-KGI-BERT: Data-Centric Knowledge Integration in Transformers for Biomedical Entity Recognition20 Jul 2023
- 2023EriBERTa: A Bilingual Pre-Trained Language Model for Clinical Natural Language Processing12 Jun 2023
- 2023DrBERT: A Robust Pre-trained Model in French for Biomedical and Clinical domains3 Apr 2023
- 2022Cross-Lingual Knowledge Transfer for Clinical Phenotyping3 Aug 2022
- 2022RigoBERTa: A State-of-the-Art Language Model For Spanish27 Apr 2022