mlsanityData to 7 Oct 2026

Machine Learning for Variance Reduction in Online Experiments

arXiv 2106.07263 ↗First posted 14 Jun 2021stat.ML cs.LGcited by 17

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Abstract (arXiv)

We consider the problem of variance reduction in randomized controlled trials, through the use of covariates correlated with the outcome but independent of the treatment. We propose a machine learning regression-adjusted treatment effect estimator, which we call MLRATE. MLRATE uses machine learning predictors of the outcome to reduce estimator variance. It employs cross-fitting to avoid overfitting biases, and we prove consistency and asymptotic normality under general conditions. MLRATE is robust to poor predictions from the machine learning step: if the predictions are uncorrelated with the outcomes, the estimator performs asymptotically no worse than the standard difference-in-means estimator, while if predictions are highly correlated with outcomes, the efficiency gains are large. In A/A tests, for a set of 48 outcome metrics commonly monitored in Facebook experiments the estimator has over 70% lower variance than the simple difference-in-means estimator, and about 19% lower variance than the common univariate procedure which adjusts only for pre-experiment values of the outcome.

Key facts. Cited by 17 papers in the map (data through 7 Oct 2026). Builds on 6 of its 50 references that are in the map. First posted on arXiv 14 Jun 2021.

Builds on

6 of 50 references.

References · 6

  1. 2017Quasi-Oracle Estimation of Heterogeneous Treatment Effectscited by 328
  2. 2016Generalized Random Forestscited by 309
  3. 2016High-dimensional regression adjustments in randomized experimentscited by 10
  4. 2017Optimization by gradient boostingcited by 5
  5. 2020No-harm calibration for generalized Oaxaca-Blinder estimatorscited by 4
  6. 2020The Generalized Oaxaca-Blinder Estimatorcited by 3

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 1; 2023: 1; 2024: 5; 2025: 4; 2026: 6.

17 papers.

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  1. 2024Variance Reduction in Ratio Metrics for Efficient Online Experimentscited by 6
  2. 2024Learning Metrics that Maximise Power for Accelerated A/B-Testscited by 6
  3. 2025On Efficient Estimation of Distributional Treatment Effects under Covariate-Adaptive Randomizationcited by 6
  4. 2024Estimating Distributional Treatment Effects in Randomized Experiments: Machine Learning for Variance Reductioncited by 5
  5. 2025t-Testing the Waters: Empirically Validating Assumptions for Reliable A/B-Testingcited by 3
  6. 2024Variance reduction combining pre-experiment and in-experiment datacited by 2
  7. 2023Causal inference with Machine Learning-Based Covariate Representationcited by 1
  8. 2025Strategic A/B testing via Maximum Probability-driven Two-armed Banditcited by 1
  9. 2025Subset Selection for Stratified Sampling in Online Controlled Experimentscited by 1
  10. 2026Unifying On- and Off-Policy Variance Reduction Methodscited by 1
  11. 2026A More Accurate Algorithm Comparison through A/B Testing using Offline Evaluation Methodscited by 1
  12. 2022Improving uplift model evaluation on RCT datacited by 0
5 more
  1. 2024STATE: A Robust ATE Estimator of Heavy-Tailed Metrics for Variance Reduction in Online Controlled Experimentscited by 0
  2. 2026Sustained Impact of Agentic Personalisation in Marketing: A Longitudinal Case Studycited by 0
  3. 2026Modeling Covariate Transition for Efficient Estimation of Longitudinal Treatment Effects in Randomized Experimentscited by 0
  4. 2026Accelerating A/B-Tests with Counterfactual Estimation: Reducing Variance through Policy Overlapcited by 0
  5. 2026Optimal Multi-way Decision Trees for Stratified Sampling in Online Controlled Experimentscited by 0