Two-stage Federated Phenotyping and Patient Representation Learning
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Abstract (arXiv)
A large percentage of medical information is in unstructured text format in electronic medical record systems. Manual extraction of information from clinical notes is extremely time consuming. Natural language processing has been widely used in recent years for automatic information extraction from medical texts. However, algorithms trained on data from a single healthcare provider are not generalizable and error-prone due to the heterogeneity and uniqueness of medical documents. We develop a two-stage federated natural language processing method that enables utilization of clinical notes from different hospitals or clinics without moving the data, and demonstrate its performance using obesity and comorbities phenotyping as medical task. This approach not only improves the quality of a specific clinical task but also facilitates knowledge progression in the whole healthcare system, which is an essential part of learning health system. To the best of our knowledge, this is the first application of federated machine learning in clinical NLP.
Key facts. Cited by 19 papers in the map (data through 14 Oct 2026). First posted on arXiv 14 Aug 2019.
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Citing papers per year: 2021: 9; 2022: 7; 2023: 0; 2024: 1; 2025: 1; 2026: 1.
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- 2021Federated Learning for Smart Healthcare: A Surveycited by 184
- 2021Federated Learning Meets Natural Language Processing: A Surveycited by 43
- 2022Federated Learning for Privacy Preservation in Smart Healthcare Systems: A Comprehensive Surveycited by 31
- 2021Semi-Synchronous Federated Learning for Energy-Efficient Training and Accelerated Convergence in Cross-Silo Settingscited by 11
- 2022Federated learning: Applications, challenges and future directionscited by 11
- 2021Scaling Neuroscience Research using Federated Learningcited by 10
- 2022Towards the Practical Utility of Federated Learning in the Medical Domaincited by 9
- 2021Self-Supervised Detection of Contextual Synonyms in a Multi-Class Setting: Phenotype Annotation Use Casecited by 7
- 2022Practical Challenges in Differentially-Private Federated Survival Analysis of Medical Datacited by 7
- 2021What Do You See in this Patient? Behavioral Testing of Clinical NLP Modelscited by 6
- 2025Federated Learning for Cyber Physical Systems: A Comprehensive Surveycited by 6
- 2021Communication-Efficient Federated Learning for Neural Machine Translationcited by 5
7 more
- 2021PMFL: Partial Meta-Federated Learning for heterogeneous tasks and its applications on real-world medical recordscited by 4
- 2021Aggregation Delayed Federated Learningcited by 2
- 2022Unsupervised Numerical Reasoning to Extract Phenotypes from Clinical Text by Leveraging External Knowledgecited by 2
- 2022Federated Named Entity Recognitioncited by 1
- 2024FedGlu: A personalized federated learning-based glucose forecasting algorithm for improved performance in glycemic excursion regionscited by 1
- 2022Construction of extra-large scale screening tools for risks of severe mental illnesses using real world healthcare datacited by 0
- 2026FedEHR-Gen: Federated Synthetic Time-Series EHR Generation via Latent Space Alignment and Distribution-Aware Aggregationcited by 0
- 2026FedEHR-Gen: Federated Synthetic Time-Series EHR Generation via Latent Space Alignment and Distribution-Aware Aggregation27 May 2026
- 2025Federated Learning for Cyber Physical Systems: A Comprehensive Survey8 May 2025
- 2024FedGlu: A personalized federated learning-based glucose forecasting algorithm for improved performance in glycemic excursion regions25 Aug 2024
- 2022Construction of extra-large scale screening tools for risks of severe mental illnesses using real world healthcare data20 Dec 2022
- 2022Towards the Practical Utility of Federated Learning in the Medical Domain7 Jul 2022
- 2022Federated learning: Applications, challenges and future directions18 May 2022
- 2022Unsupervised Numerical Reasoning to Extract Phenotypes from Clinical Text by Leveraging External Knowledge19 Apr 2022
- 2022Federated Named Entity Recognition28 Mar 2022
- 2022Federated Learning for Privacy Preservation in Smart Healthcare Systems: A Comprehensive Survey18 Mar 2022
- 2022Practical Challenges in Differentially-Private Federated Survival Analysis of Medical Data8 Feb 2022
- 2021Communication-Efficient Federated Learning for Neural Machine Translation12 Dec 2021
- 2021PMFL: Partial Meta-Federated Learning for heterogeneous tasks and its applications on real-world medical records10 Dec 2021
7 more
- 2021What Do You See in this Patient? Behavioral Testing of Clinical NLP Models30 Nov 2021
- 2021Federated Learning for Smart Healthcare: A Survey16 Nov 2021
- 2021Self-Supervised Detection of Contextual Synonyms in a Multi-Class Setting: Phenotype Annotation Use Case4 Sep 2021
- 2021Aggregation Delayed Federated Learning17 Aug 2021
- 2021Federated Learning Meets Natural Language Processing: A Survey27 Jul 2021
- 2021Scaling Neuroscience Research using Federated Learning16 Feb 2021
- 2021Semi-Synchronous Federated Learning for Energy-Efficient Training and Accelerated Convergence in Cross-Silo Settings4 Feb 2021
- 2021Federated Learning for Smart Healthcare: A Surveycited by 184
- 2021Federated Learning Meets Natural Language Processing: A Surveycited by 43
- 2022Federated Learning for Privacy Preservation in Smart Healthcare Systems: A Comprehensive Surveycited by 31
- 2021Semi-Synchronous Federated Learning for Energy-Efficient Training and Accelerated Convergence in Cross-Silo Settingscited by 11
- 2022Federated learning: Applications, challenges and future directionscited by 11
- 2021Scaling Neuroscience Research using Federated Learningcited by 10
- 2022Towards the Practical Utility of Federated Learning in the Medical Domaincited by 9
- 2021Self-Supervised Detection of Contextual Synonyms in a Multi-Class Setting: Phenotype Annotation Use Casecited by 7
- 2022Practical Challenges in Differentially-Private Federated Survival Analysis of Medical Datacited by 7
- 2021What Do You See in this Patient? Behavioral Testing of Clinical NLP Modelscited by 6
- 2025Federated Learning for Cyber Physical Systems: A Comprehensive Surveycited by 6
- 2021Communication-Efficient Federated Learning for Neural Machine Translationcited by 5
12 most cited of 19 All 19 (JSON)
- 2026FedEHR-Gen: Federated Synthetic Time-Series EHR Generation via Latent Space Alignment and Distribution-Aware Aggregation27 May 2026
- 2025Federated Learning for Cyber Physical Systems: A Comprehensive Survey8 May 2025
- 2024FedGlu: A personalized federated learning-based glucose forecasting algorithm for improved performance in glycemic excursion regions25 Aug 2024
- 2022Construction of extra-large scale screening tools for risks of severe mental illnesses using real world healthcare data20 Dec 2022
- 2022Towards the Practical Utility of Federated Learning in the Medical Domain7 Jul 2022
- 2022Federated learning: Applications, challenges and future directions18 May 2022
- 2022Unsupervised Numerical Reasoning to Extract Phenotypes from Clinical Text by Leveraging External Knowledge19 Apr 2022
- 2022Federated Named Entity Recognition28 Mar 2022
- 2022Federated Learning for Privacy Preservation in Smart Healthcare Systems: A Comprehensive Survey18 Mar 2022
- 2022Practical Challenges in Differentially-Private Federated Survival Analysis of Medical Data8 Feb 2022
- 2021Communication-Efficient Federated Learning for Neural Machine Translation12 Dec 2021
- 2021PMFL: Partial Meta-Federated Learning for heterogeneous tasks and its applications on real-world medical records10 Dec 2021
12 newest of 19 All 19 (JSON)