Reducing Uncertainty in Undersampled MRI Reconstruction with Active Acquisition
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Abstract (arXiv)
The goal of MRI reconstruction is to restore a high fidelity image from partially observed measurements. This partial view naturally induces reconstruction uncertainty that can only be reduced by acquiring additional measurements. In this paper, we present a novel method for MRI reconstruction that, at inference time, dynamically selects the measurements to take and iteratively refines the prediction in order to best reduce the reconstruction error and, thus, its uncertainty. We validate our method on a large scale knee MRI dataset, as well as on ImageNet. Results show that (1) our system successfully outperforms active acquisition baselines; (2) our uncertainty estimates correlate with error maps; and (3) our ResNet-based architecture surpasses standard pixel-to-pixel models in the task of MRI reconstruction. The proposed method not only shows high-quality reconstructions but also paves the road towards more applicable solutions for accelerating MRI.
Key facts. Cited by 55 papers in the map (data through 7 Oct 2026). First posted on arXiv 8 Feb 2019.
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Citing papers per year: 2021: 12; 2022: 11; 2023: 15; 2024: 7; 2025: 3; 2026: 7.
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- 2023A Review of Uncertainty Estimation and its Application in Medical Imagingcited by 59
- 2023Learning Federated Visual Prompt in Null Space for MRI Reconstructioncited by 40
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methodscited by 39
- 2021Deep reinforcement learning in medical imaging: A literature reviewcited by 34
- 2021Active 3D Shape Reconstruction from Vision and Touchcited by 34
- 2023A comprehensive survey on deep active learning in medical image analysiscited by 32
- 2022DSFormer: A Dual-domain Self-supervised Transformer for Accelerated Multi-contrast MRI Reconstructioncited by 30
- 2021A Survey on Epistemic (Model) Uncertainty in Supervised Learning: Recent Advances and Applicationscited by 24
- 2021Uncertainty-Guided Progressive GANs for Medical Image Translationcited by 16
- 2021Uncertainty-aware GAN with Adaptive Loss for Robust MRI Image Enhancementcited by 15
- 2022ZigZag: Universal Sampling-free Uncertainty Estimation Through Two-Step Inferencecited by 15
- 2022On learning adaptive acquisition policies for undersampled multi-coil MRI reconstructioncited by 14
38 more
- 2021End-to-End Sequential Sampling and Reconstruction for MRIcited by 13
- 2021A review and experimental evaluation of deep learning methods for MRI reconstructioncited by 13
- 2023Dual-Domain Self-Supervised Learning for Accelerated Non-Cartesian MRI Reconstructioncited by 13
- 2023On Retrospective k-space Subsampling schemes For Deep MRI Reconstructioncited by 12
- 2024Adaptive Compressed Sensing with Diffusion-Based Posterior Samplingcited by 12
- 2022Learning Optimal K-space Acquisition and Reconstruction using Physics-Informed Neural Networkscited by 11
- 2022Dual-Domain Reconstruction Networks with V-Net and K-Net for fast MRIcited by 8
- 2024Adaptive Sampling of k-Space in Magnetic Resonance for Rapid Pathology Predictioncited by 7
- 2022PUERT: Probabilistic Under-sampling and Explicable Reconstruction Network for CS-MRIcited by 5
- 2021Towards Robust Active Feature Acquisitioncited by 4
- 2023USIM-DAL: Uncertainty-aware Statistical Image Modeling-based Dense Active Learning for Super-resolutioncited by 4
- 2025Diffusion Active Learning: Towards Data-Driven Experimental Design in Computed Tomographycited by 4
- 2022JoJoNet: Joint-contrast and Joint-sampling-and-reconstruction Network for Multi-contrast MRIcited by 3
- 2022Active CT Reconstruction with a Learned Sampling Policycited by 3
- 2023On the Feasibility of Machine Learning Augmented Magnetic Resonance for Point-of-Care Identification of Diseasecited by 3
- 2023PixCUE: Joint Uncertainty Estimation and Image Reconstruction in MRI using Deep Pixel Classificationcited by 3
- 2023Learning Task-Specific Strategies for Accelerated MRIcited by 3
- 2021Deep MRI Reconstruction with Radial Subsamplingcited by 2
- 2021Fast T2w/FLAIR MRI Acquisition by Optimal Sampling of Information Complementary to Pre-acquired T1w MRIcited by 2
- 2023Uncertainty Estimation in Contrast-Enhanced MR Image Translation with Multi-Axis Fusioncited by 2
- 2024The MRI Scanner as a Diagnostic: Image-less Active Samplingcited by 2
- 2024Adaptive Selection of Sampling-Reconstruction in Fourier Compressed Sensingcited by 2
- 2021Real-Time Mapping of Tissue Properties for Magnetic Resonance Fingerprintingcited by 1
- 2022Active Phase-Encode Selection for Slice-Specific Fast MR Scanning Using a Transformer-Based Deep Reinforcement Learning Frameworkcited by 1
- 2022A Path Towards Clinical Adaptation of Accelerated MRIcited by 1
- 2023Variational Imbalanced Regression: Fair Uncertainty Quantification via Probabilistic Smoothingcited by 1
- 2023On the Quantification of Image Reconstruction Uncertainty without Training Datacited by 1
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstructioncited by 1
- 2025Active Sampling for MRI-based Sequential Decision Makingcited by 1
- 2026ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesiscited by 1
- 2026SIREM: Speech-Informed MRI Reconstruction with Learned Samplingcited by 1
- 2021Unsupervised Embedding Learning from Uncertainty Momentum Modelingcited by 0
- 2022L2SR: Learning to Sample and Reconstruct for Accelerated MRI via Reinforcement Learningcited by 0
- 2023ALUM: Adversarial Data Uncertainty Modeling from Latent Model Uncertainty Compensationcited by 0
- 2023Reinforcement Learning for Sampling on Temporal Medical Imaging Sequencescited by 0
- 2024LSST: Learned Single-Shot Trajectory and Reconstruction Network for MR Imagingcited by 0
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstructioncited by 0
- 2025Adaptive Mask-guided K-space Diffusion for Accelerated MRI Reconstructioncited by 0
50 most cited of 55 All 55 (JSON)
- 2026GPARA: Graph-Posterior-Aligned Refinement and Active Acquisition for Grounding Diffusion Priors28 Sep 2026
- 2026OpenMASC: An Open-Source Pipeline for Cross-Trajectory Metal-Aware Sampling and Correction in Accelerated MRI26 Sep 2026
- 2026Prior-aware and Context-guided Group Sampling for Active Probabilistic Subsampling8 Jul 2026
- 2026SIREM: Speech-Informed MRI Reconstruction with Learned Sampling18 May 2026
- 2026Information-Theoretic Optimization for Task-Adapted Compressed Sensing Magnetic Resonance Imaging14 Apr 2026
- 2026ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesis11 Mar 2026
- 2026MASC: Metal-Aware Sampling and Correction via Reinforcement Learning for Accelerated MRI30 Jan 2026
- 2025Adaptive Mask-guided K-space Diffusion for Accelerated MRI Reconstruction23 Jun 2025
- 2025Active Sampling for MRI-based Sequential Decision Making7 May 2025
- 2025Diffusion Active Learning: Towards Data-Driven Experimental Design in Computed Tomography4 Apr 2025
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstruction31 Oct 2024
- 2024Adaptive Selection of Sampling-Reconstruction in Fourier Compressed Sensing18 Sep 2024
38 more
- 2024LSST: Learned Single-Shot Trajectory and Reconstruction Network for MR Imaging8 Aug 2024
- 2024Adaptive Compressed Sensing with Diffusion-Based Posterior Sampling11 Jul 2024
- 2024The MRI Scanner as a Diagnostic: Image-less Active Sampling24 Jun 2024
- 2024Adaptive Sampling of k-Space in Magnetic Resonance for Rapid Pathology Prediction6 Jun 2024
- 2024DuDoUniNeXt: Dual-domain unified hybrid model for single and multi-contrast undersampled MRI reconstruction8 Mar 2024
- 2023Uncertainty Estimation in Contrast-Enhanced MR Image Translation with Multi-Axis Fusion20 Nov 2023
- 2023On the Quantification of Image Reconstruction Uncertainty without Training Data16 Nov 2023
- 2023A comprehensive survey on deep active learning in medical image analysis22 Oct 2023
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methods9 Oct 2023
- 2023Reinforcement Learning for Sampling on Temporal Medical Imaging Sequences28 Aug 2023
- 2023Variational Imbalanced Regression: Fair Uncertainty Quantification via Probabilistic Smoothing11 Jun 2023
- 2023USIM-DAL: Uncertainty-aware Statistical Image Modeling-based Dense Active Learning for Super-resolution27 May 2023
- 2023Learning Task-Specific Strategies for Accelerated MRI25 Apr 2023
- 2023ALUM: Adversarial Data Uncertainty Modeling from Latent Model Uncertainty Compensation29 Mar 2023
- 2023Learning Federated Visual Prompt in Null Space for MRI Reconstruction28 Mar 2023
- 2023PixCUE: Joint Uncertainty Estimation and Image Reconstruction in MRI using Deep Pixel Classification28 Feb 2023
- 2023Dual-Domain Self-Supervised Learning for Accelerated Non-Cartesian MRI Reconstruction18 Feb 2023
- 2023A Review of Uncertainty Estimation and its Application in Medical Imaging16 Feb 2023
- 2023On the Feasibility of Machine Learning Augmented Magnetic Resonance for Point-of-Care Identification of Disease27 Jan 2023
- 2023On Retrospective k-space Subsampling schemes For Deep MRI Reconstruction20 Jan 2023
- 2022L2SR: Learning to Sample and Reconstruct for Accelerated MRI via Reinforcement Learning5 Dec 2022
- 2022ZigZag: Universal Sampling-free Uncertainty Estimation Through Two-Step Inference21 Nov 2022
- 2022Active CT Reconstruction with a Learned Sampling Policy3 Nov 2022
- 2022JoJoNet: Joint-contrast and Joint-sampling-and-reconstruction Network for Multi-contrast MRI22 Oct 2022
- 2022A Path Towards Clinical Adaptation of Accelerated MRI26 Aug 2022
- 2022PUERT: Probabilistic Under-sampling and Explicable Reconstruction Network for CS-MRI24 Apr 2022
- 2022Learning Optimal K-space Acquisition and Reconstruction using Physics-Informed Neural Networks5 Apr 2022
- 2022On learning adaptive acquisition policies for undersampled multi-coil MRI reconstruction30 Mar 2022
- 2022Active Phase-Encode Selection for Slice-Specific Fast MR Scanning Using a Transformer-Based Deep Reinforcement Learning Framework11 Mar 2022
- 2022Dual-Domain Reconstruction Networks with V-Net and K-Net for fast MRI11 Mar 2022
- 2022DSFormer: A Dual-domain Self-supervised Transformer for Accelerated Multi-contrast MRI Reconstruction26 Jan 2022
- 2021Fast T2w/FLAIR MRI Acquisition by Optimal Sampling of Information Complementary to Pre-acquired T1w MRI11 Nov 2021
- 2021A Survey on Epistemic (Model) Uncertainty in Supervised Learning: Recent Advances and Applications3 Nov 2021
- 2021Uncertainty-aware GAN with Adaptive Loss for Robust MRI Image Enhancement7 Oct 2021
- 2021A review and experimental evaluation of deep learning methods for MRI reconstruction17 Sep 2021
- 2021Deep MRI Reconstruction with Radial Subsampling17 Aug 2021
- 2021Active 3D Shape Reconstruction from Vision and Touch20 Jul 2021
- 2021Unsupervised Embedding Learning from Uncertainty Momentum Modeling19 Jul 2021
50 newest of 55 All 55 (JSON)
- 2025Diffusion Active Learning: Towards Data-Driven Experimental Design in Computed Tomographycited by 4
- 2026ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesiscited by 1
- 2026GPARA: Graph-Posterior-Aligned Refinement and Active Acquisition for Grounding Diffusion Priorscited by 0
- 2026GPARA: Graph-Posterior-Aligned Refinement and Active Acquisition for Grounding Diffusion Priors28 Sep 2026
- 2026ReDiff: Reliability-Guided Diffusion for Trustworthy Ultra-Low-Field to High-Field MRI Synthesis11 Mar 2026
- 2025Diffusion Active Learning: Towards Data-Driven Experimental Design in Computed Tomography4 Apr 2025
- 2023A Review of Uncertainty Estimation and its Application in Medical Imagingcited by 59
- 2023Learning Federated Visual Prompt in Null Space for MRI Reconstructioncited by 40
- 2023A review of uncertainty quantification in medical image analysis: probabilistic and non-probabilistic methodscited by 39
- 2021Deep reinforcement learning in medical imaging: A literature reviewcited by 34
- 2021Active 3D Shape Reconstruction from Vision and Touchcited by 34
- 2023A comprehensive survey on deep active learning in medical image analysiscited by 32
- 2022DSFormer: A Dual-domain Self-supervised Transformer for Accelerated Multi-contrast MRI Reconstructioncited by 30
- 2021A Survey on Epistemic (Model) Uncertainty in Supervised Learning: Recent Advances and Applicationscited by 24
- 2021Uncertainty-Guided Progressive GANs for Medical Image Translationcited by 16
- 2021Uncertainty-aware GAN with Adaptive Loss for Robust MRI Image Enhancementcited by 15
- 2022ZigZag: Universal Sampling-free Uncertainty Estimation Through Two-Step Inferencecited by 15
- 2022On learning adaptive acquisition policies for undersampled multi-coil MRI reconstructioncited by 14
12 most cited of 52 All 52 (JSON)
- 2026OpenMASC: An Open-Source Pipeline for Cross-Trajectory Metal-Aware Sampling and Correction in Accelerated MRI26 Sep 2026
- 2026Prior-aware and Context-guided Group Sampling for Active Probabilistic Subsampling8 Jul 2026
- 2026SIREM: Speech-Informed MRI Reconstruction with Learned Sampling18 May 2026
- 2026Information-Theoretic Optimization for Task-Adapted Compressed Sensing Magnetic Resonance Imaging14 Apr 2026
- 2026MASC: Metal-Aware Sampling and Correction via Reinforcement Learning for Accelerated MRI30 Jan 2026
- 2025Adaptive Mask-guided K-space Diffusion for Accelerated MRI Reconstruction23 Jun 2025
- 2025Active Sampling for MRI-based Sequential Decision Making7 May 2025
- 2024MS-Glance: Bio-Insipred Non-semantic Context Vectors and their Applications in Supervising Image Reconstruction31 Oct 2024
- 2024Adaptive Selection of Sampling-Reconstruction in Fourier Compressed Sensing18 Sep 2024
- 2024LSST: Learned Single-Shot Trajectory and Reconstruction Network for MR Imaging8 Aug 2024
- 2024Adaptive Compressed Sensing with Diffusion-Based Posterior Sampling11 Jul 2024
- 2024The MRI Scanner as a Diagnostic: Image-less Active Sampling24 Jun 2024
12 newest of 52 All 52 (JSON)