Disc-aware Ensemble Network for Glaucoma Screening from Fundus Image
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Abstract (arXiv)
Glaucoma is a chronic eye disease that leads to irreversible vision loss. Most of the existing automatic screening methods firstly segment the main structure, and subsequently calculate the clinical measurement for detection and screening of glaucoma. However, these measurement-based methods rely heavily on the segmentation accuracy, and ignore various visual features. In this paper, we introduce a deep learning technique to gain additional image-relevant information, and screen glaucoma from the fundus image directly. Specifically, a novel Disc-aware Ensemble Network (DENet) for automatic glaucoma screening is proposed, which integrates the deep hierarchical context of the global fundus image and the local optic disc region. Four deep streams on different levels and modules are respectively considered as global image stream, segmentation-guided network, local disc region stream, and disc polar transformation stream. Finally, the output probabilities of different streams are fused as the final screening result. The experiments on two glaucoma datasets (SCES and new SINDI datasets) show our method outperforms other state-of-the-art algorithms.
Key facts. Cited by 39 papers in the map (data through 7 Oct 2026). First posted on arXiv 19 May 2018.
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Citing papers per year: 2021: 10; 2022: 9; 2023: 5; 2024: 8; 2025: 5; 2026: 2.
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- 2021Applications of Deep Learning in Fundus Images: A Reviewcited by 59
- 2022GAMMA Challenge:Glaucoma grAding from Multi-Modality imAgescited by 45
- 2023Harvard Glaucoma Fairness: A Retinal Nerve Disease Dataset for Fairness Learning and Fair Identity Normalizationcited by 31
- 2021VTGAN: Semi-supervised Retinal Image Synthesis and Disease Prediction using Vision Transformerscited by 28
- 2021Relational Subsets Knowledge Distillation for Long-tailed Retinal Diseases Recognitioncited by 27
- 2022ADAM Challenge: Detecting Age-related Macular Degeneration from Fundus Imagescited by 25
- 2021Hierarchical Knowledge Guided Learning for Real-world Retinal Diseases Recognitioncited by 10
- 2021Deep learning on fundus images detects glaucoma beyond the optic disccited by 9
- 2022SeATrans: Learning Segmentation-Assisted diagnosis model via Transformercited by 8
- 2022Discriminative Kernel Convolution Network for Multi-Label Ophthalmic Disease Detection on Imbalanced Fundus Image Datasetcited by 6
- 2024Non-Invasive to Invasive: Enhancing FFA Synthesis from CFP with a Benchmark Dataset and a Novel Networkcited by 6
- 2021CADA: Multi-scale Collaborative Adversarial Domain Adaptation for Unsupervised Optic Disc and Cup Segmentationcited by 5
27 more
- 2023Evaluate underdiagnosis and overdiagnosis bias of deep learning model on primary open-angle glaucoma diagnosis in under-served patient populationscited by 5
- 2023Deep Learning and Computer Vision for Glaucoma Detection: A Reviewcited by 4
- 2025Interpretable Few-Shot Retinal Disease Diagnosis with Concept-Guided Prompting of Vision-Language Modelscited by 4
- 2022Opinions Vary? Diagnosis First!cited by 3
- 2022Calibrate the inter-observer segmentation uncertainty via diagnosis-first principlecited by 3
- 2024FRCNet Frequency and Region Consistency for Semi-supervised Medical Image Segmentationcited by 3
- 2025GONet: A Generalizable Deep Learning Model for Glaucoma Detectioncited by 3
- 2021I-ODA, Real-World Multi-modal Longitudinal Data for OphthalmicApplicationscited by 2
- 2025FundusGAN: A Hierarchical Feature-Aware Generative Framework for High-Fidelity Fundus Image Generationcited by 2
- 2021U-Net with Hierarchical Bottleneck Attention for Landmark Detection in Fundus Images of the Degenerated Retinacited by 1
- 2022Label uncertainty-guided multi-stream model for disease screeningcited by 1
- 2022ExpNet: A unified network for Expert-Level Classificationcited by 1
- 2024Soft Dice Confidence: A Near-Optimal Confidence Estimator for Selective Prediction in Semantic Segmentationcited by 1
- 2025Enhancing Diabetic Retinopathy Classification Accuracy through Dual Attention Mechanism in Deep Learningcited by 1
- 2021Rapid Classification of Glaucomatous Fundus Imagescited by 0
- 2021Self-Adaptive Transfer Learning for Multicenter Glaucoma Classification in Fundus Retina Imagescited by 0
- 2022Learning to screen Glaucoma like the ophthalmologistscited by 0
- 2023EDDense-Net: Fully Dense Encoder Decoder Network for Joint Segmentation of Optic Cup and Disccited by 0
- 2023Exploring Deep Learning Techniques for Glaucoma Detection: A Comprehensive Reviewcited by 0
- 2024Not just Birds and Cars: Generic, Scalable and Explainable Models for Professional Visual Recognitioncited by 0
- 2024Multiscale Color Guided Attention Ensemble Classifier for Age-Related Macular Degeneration using Concurrent Fundus and Optical Coherence Tomography Imagescited by 0
- 2024GS-Net: Global Self-Attention Guided CNN for Multi-Stage Glaucoma Classificationcited by 0
- 2024AI-Driven Approaches for Glaucoma Detection -- A Comprehensive Reviewcited by 0
- 2024Trends, Challenges, and Future Directions in Deep Learning for Glaucoma: A Systematic Reviewcited by 0
- 2025Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Imagescited by 0
- 2026GLEAM: A Multimodal Imaging Dataset and HAMM for Glaucoma Classificationcited by 0
- 2026Nested Radially Monotone Polar Occupancy Estimation: Clinically-Grounded Optic Disc and Cup Segmentation for Glaucoma Screeningcited by 0
- 2026Nested Radially Monotone Polar Occupancy Estimation: Clinically-Grounded Optic Disc and Cup Segmentation for Glaucoma Screening10 Apr 2026
- 2026GLEAM: A Multimodal Imaging Dataset and HAMM for Glaucoma Classification13 Mar 2026
- 2025Enhancing Diabetic Retinopathy Classification Accuracy through Dual Attention Mechanism in Deep Learning25 Jul 2025
- 2025Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images26 Jun 2025
- 2025FundusGAN: A Hierarchical Feature-Aware Generative Framework for High-Fidelity Fundus Image Generation22 Mar 2025
- 2025Interpretable Few-Shot Retinal Disease Diagnosis with Concept-Guided Prompting of Vision-Language Models4 Mar 2025
- 2025GONet: A Generalizable Deep Learning Model for Glaucoma Detection26 Feb 2025
- 2024Trends, Challenges, and Future Directions in Deep Learning for Glaucoma: A Systematic Review7 Nov 2024
- 2024AI-Driven Approaches for Glaucoma Detection -- A Comprehensive Review21 Oct 2024
- 2024Non-Invasive to Invasive: Enhancing FFA Synthesis from CFP with a Benchmark Dataset and a Novel Network19 Oct 2024
- 2024GS-Net: Global Self-Attention Guided CNN for Multi-Stage Glaucoma Classification24 Sep 2024
- 2024Multiscale Color Guided Attention Ensemble Classifier for Age-Related Macular Degeneration using Concurrent Fundus and Optical Coherence Tomography Images1 Sep 2024
27 more
- 2024FRCNet Frequency and Region Consistency for Semi-supervised Medical Image Segmentation26 May 2024
- 2024Not just Birds and Cars: Generic, Scalable and Explainable Models for Professional Visual Recognition8 Mar 2024
- 2024Soft Dice Confidence: A Near-Optimal Confidence Estimator for Selective Prediction in Semantic Segmentation16 Feb 2024
- 2023Exploring Deep Learning Techniques for Glaucoma Detection: A Comprehensive Review2 Nov 2023
- 2023EDDense-Net: Fully Dense Encoder Decoder Network for Joint Segmentation of Optic Cup and Disc20 Aug 2023
- 2023Deep Learning and Computer Vision for Glaucoma Detection: A Review31 Jul 2023
- 2023Harvard Glaucoma Fairness: A Retinal Nerve Disease Dataset for Fairness Learning and Fair Identity Normalization15 Jun 2023
- 2023Evaluate underdiagnosis and overdiagnosis bias of deep learning model on primary open-angle glaucoma diagnosis in under-served patient populations26 Jan 2023
- 2022ExpNet: A unified network for Expert-Level Classification29 Nov 2022
- 2022Learning to screen Glaucoma like the ophthalmologists23 Sep 2022
- 2022Calibrate the inter-observer segmentation uncertainty via diagnosis-first principle5 Aug 2022
- 2022Discriminative Kernel Convolution Network for Multi-Label Ophthalmic Disease Detection on Imbalanced Fundus Image Dataset16 Jul 2022
- 2022SeATrans: Learning Segmentation-Assisted diagnosis model via Transformer12 Jun 2022
- 2022ADAM Challenge: Detecting Age-related Macular Degeneration from Fundus Images16 Feb 2022
- 2022GAMMA Challenge:Glaucoma grAding from Multi-Modality imAges14 Feb 2022
- 2022Opinions Vary? Diagnosis First!14 Feb 2022
- 2022Label uncertainty-guided multi-stream model for disease screening28 Jan 2022
- 2021Hierarchical Knowledge Guided Learning for Real-world Retinal Diseases Recognition17 Nov 2021
- 2021CADA: Multi-scale Collaborative Adversarial Domain Adaptation for Unsupervised Optic Disc and Cup Segmentation5 Oct 2021
- 2021U-Net with Hierarchical Bottleneck Attention for Landmark Detection in Fundus Images of the Degenerated Retina9 Jul 2021
- 2021Self-Adaptive Transfer Learning for Multicenter Glaucoma Classification in Fundus Retina Images7 May 2021
- 2021Relational Subsets Knowledge Distillation for Long-tailed Retinal Diseases Recognition22 Apr 2021
- 2021VTGAN: Semi-supervised Retinal Image Synthesis and Disease Prediction using Vision Transformers14 Apr 2021
- 2021I-ODA, Real-World Multi-modal Longitudinal Data for OphthalmicApplications30 Mar 2021
- 2021Deep learning on fundus images detects glaucoma beyond the optic disc22 Mar 2021
- 2021Rapid Classification of Glaucomatous Fundus Images8 Feb 2021
- 2021Applications of Deep Learning in Fundus Images: A Review25 Jan 2021
- 2021Applications of Deep Learning in Fundus Images: A Reviewcited by 59
- 2022GAMMA Challenge:Glaucoma grAding from Multi-Modality imAgescited by 45
- 2023Harvard Glaucoma Fairness: A Retinal Nerve Disease Dataset for Fairness Learning and Fair Identity Normalizationcited by 31
- 2021VTGAN: Semi-supervised Retinal Image Synthesis and Disease Prediction using Vision Transformerscited by 28
- 2021Relational Subsets Knowledge Distillation for Long-tailed Retinal Diseases Recognitioncited by 27
- 2022ADAM Challenge: Detecting Age-related Macular Degeneration from Fundus Imagescited by 25
- 2021Hierarchical Knowledge Guided Learning for Real-world Retinal Diseases Recognitioncited by 10
- 2021Deep learning on fundus images detects glaucoma beyond the optic disccited by 9
- 2022SeATrans: Learning Segmentation-Assisted diagnosis model via Transformercited by 8
- 2022Discriminative Kernel Convolution Network for Multi-Label Ophthalmic Disease Detection on Imbalanced Fundus Image Datasetcited by 6
- 2024Non-Invasive to Invasive: Enhancing FFA Synthesis from CFP with a Benchmark Dataset and a Novel Networkcited by 6
- 2021CADA: Multi-scale Collaborative Adversarial Domain Adaptation for Unsupervised Optic Disc and Cup Segmentationcited by 5
12 most cited of 38 All 38 (JSON)
- 2026Nested Radially Monotone Polar Occupancy Estimation: Clinically-Grounded Optic Disc and Cup Segmentation for Glaucoma Screening10 Apr 2026
- 2026GLEAM: A Multimodal Imaging Dataset and HAMM for Glaucoma Classification13 Mar 2026
- 2025Enhancing Diabetic Retinopathy Classification Accuracy through Dual Attention Mechanism in Deep Learning25 Jul 2025
- 2025Early Glaucoma Detection using Deep Learning with Multiple Datasets of Fundus Images26 Jun 2025
- 2025FundusGAN: A Hierarchical Feature-Aware Generative Framework for High-Fidelity Fundus Image Generation22 Mar 2025
- 2025GONet: A Generalizable Deep Learning Model for Glaucoma Detection26 Feb 2025
- 2024Trends, Challenges, and Future Directions in Deep Learning for Glaucoma: A Systematic Review7 Nov 2024
- 2024AI-Driven Approaches for Glaucoma Detection -- A Comprehensive Review21 Oct 2024
- 2024Non-Invasive to Invasive: Enhancing FFA Synthesis from CFP with a Benchmark Dataset and a Novel Network19 Oct 2024
- 2024GS-Net: Global Self-Attention Guided CNN for Multi-Stage Glaucoma Classification24 Sep 2024
- 2024Multiscale Color Guided Attention Ensemble Classifier for Age-Related Macular Degeneration using Concurrent Fundus and Optical Coherence Tomography Images1 Sep 2024
- 2024FRCNet Frequency and Region Consistency for Semi-supervised Medical Image Segmentation26 May 2024
12 newest of 38 All 38 (JSON)