IMC-CLINIC: Coupled Loss-Informed Newton Iterations for Clipping in Analog In-Memory Computing

Analog in-memory computing (IMC) offers a promising path toward energy-efficient large language model (LLM) inference by executing matrix multiplications (MatMul) directly within memory arrays in the analog domain. Its efficiency, however, comes with an additional source of error: limited-precision analog-to-digital converters (ADCs) quantize accumulated analog partial sums, introducing output-side error distinct from conventional activation and weight quantization at the MatMul inputs. Clipping can mitigate both operand and ADC quantization errors, but the optimal clipping factors must jointly balance activation rounding and clipping, weight rounding and clipping, and ADC quantization. Existing clipping methods, designed for digital quantization, do not explicitly optimize these coupled sources of IMC error and often rely on costly search-based calibration. We introduce IMC-CLINIC (Coupled Loss-Informed Newton Iterations for Clipping), a clipping calibration framework based on an analytical surrogate for IMC MatMul output error. The surrogate jointly models operand quantization, accumulated clipping-induced bias, and ADC quantization, enabling efficient evaluation of its gradient and approximate curvature from a small calibration set. IMC-CLINIC jointly optimizes activation and weight clipping factors using a safeguarded Newton-type method. Across multiple models and datasets, it improves average zero-shot accuracy by 6.5-11.5 percentage points over the grid search baseline while reducing calibration time by factors of 10.0-12.1. Its analytical surrogate closely tracks empirical IMC output error, and its optimizer is certified within 1% of the global optimum under the loss objective across all projections on two representative models.