mlsanityData to 7 Oct 2026

ECG Mirage: Revealing and Mitigating the Underutilisation of ECGs in Vision-Language Models for Clinical Prediction

arXiv 2609.21755 ↗First posted 18 Sep 2026cs.AIcited by 0

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Abstract (arXiv)

Emergency department (ED) decision-making relies on heterogeneous clinical information, including patient history, vital signs, laboratory results, and electrocardiograms (ECGs). Vision--language models (VLMs) can jointly process these modalities, but strong predictive performance does not necessarily imply meaningful use of the correct patient's ECG. We term this failure mode ECG Mirage: apparent multimodal capability without useful dependence on patient-specific ECG information. We distinguish two forms: ECG neglect, where ECGs provide little predictive benefit, and ECG confusion, where matched ECGs outperform no-image inputs but not mismatched ECGs. To evaluate these behaviours, we compare predictions obtained with matched ECGs, outcome-discordant mismatched ECGs, and no-image inputs while holding the clinical text and prediction targets fixed. Across four VLMs on MDS-ED, matched ECGs provide no consistent advantage for either ICU admission or clinical deterioration prediction. We then train four restricted visual prompts using supervised learning followed by conditional direct preference optimisation, while keeping the VLM backbone frozen. The resulting models achieve balanced accuracies of 70.6% for ICU admission and 67.5% for deterioration and increase the matched-versus-mismatched performance gap to approximately 16.5 and 5.5 percentage points, respectively. Overall, our study identifies ECG Mirage in multimodal clinical prediction and introduces visual prompt tuning as an efficient mitigation strategy.

Key facts. No citing papers in the map yet (data through 7 Oct 2026). Builds on 16 of its 23 references that are in the map. First posted on arXiv 18 Sep 2026.

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References · 16

  1. 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
  2. 2023Direct Preference Optimization: Your Language Model is Secretly a Reward Modelcited by 7,916
  3. 2021The Power of Scale for Parameter-Efficient Prompt Tuningcited by 3,769
  4. 2022Visual Prompt Tuningcited by 1,674
  5. 2024Are We on the Right Way for Evaluating Large Vision-Language Models?cited by 893
  6. 2026Gemma 4 Technical Reportcited by 187
  7. 2024mDPO: Conditional Preference Optimization for Multimodal Large Language Modelscited by 92
  8. 2026MedGemma 1.5 Technical Reportcited by 43
  9. 2025GEM: Empowering MLLM for Grounded ECG Understanding with Time Series and Imagescited by 35
  10. 2023Multimodal Clinical Benchmark for Emergency Care (MC-BEC): A Comprehensive Benchmark for Evaluating Foundation Models in Emergency Medicinecited by 24
  11. 2023Multimodal Foundation Models Exploit Text to Make Medical Image Predictionscited by 19
  12. 2024Enhancing clinical decision support with physiological waveforms -- a multimodal benchmark in emergency carecited by 13
4 more
  1. 2025Bridging Data Gaps of Rare Conditions in ICU: A Multi-Disease Adaptation Approach for Clinical Predictioncited by 4
  2. 2025Cross-Representation Benchmarking in Time-Series Electronic Health Records for Clinical Outcome Predictioncited by 4
  3. 2026The Taxonomies, Training, and Applications of Event Stream Modelling for Electronic Health Recordscited by 3
  4. 2026From Token to Token Pair: Efficient Prompt Compression for Large Language Models in Clinical Predictioncited by 2

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  1. 2026ECGQuest: Benchmarking and Fine-Tuning Language Models for Electrocardiography
  2. 2026ECG-Reasoning-Benchmark: A Benchmark for Evaluating Clinical Reasoning Capabilities in ECG Interpretation
  3. 2026Physiology-Aware CNN and Zero-Shot Multimodal LLMs for ECG Image Classification: A Comparative Study
  4. 2026ECG-R1: Protocol-Guided and Modality-Agnostic MLLM for Reliable ECG Interpretation
  5. 2024Teach Multimodal LLMs to Comprehend Electrocardiographic Images
  6. 2026Enhancing Explainable Cardiac Diagnosis with Guide-Grounded Multimodal LLMs
  7. 2025ECG-LLM -- training and evaluation of domain-specific large language models for electrocardiography
  8. 2026Reasoning Before Diagnosis: Physician-Inspired Structured Thinking for ECG Classification