Reliability- and Anatomy-Consistency-Aware Multimodal Learning for Robust Fracture Classification from Bangladeshi Radiographs
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Abstract (arXiv)
Background: Multimodal fracture classifiers may benefit from patient and anatomical metadata, but they can also become brittle when contextual information is missing or mismatched. Methods: We studied 1493 radiographs from the Bangladeshi OrthoFrac-XR dataset using leakage-safe age, sex, bone type, and laterality. A ConvNeXt image encoder was combined with a clinical multilayer perceptron through concatenation, late fusion, reliability-gated residual fusion, and a hierarchical state-location formulation. We additionally introduced an anatomy-consistency gate that attenuates metadata corrections when an image-side anatomical prediction disagrees with the reported bone type. Results: Across five folds and three seeds, hierarchical residual fusion achieved a macro-F1 of 0.6046 +/- 0.0279, compared with 0.5727 +/- 0.0270 for image-only learning, while improving the Brier score from 0.5239 to 0.4948. In a five-fold robustness experiment, anatomy-consistency fusion reduced the macro-F1 loss under shuffled metadata from 0.0567 to 0.0203 relative to ordinary residual fusion, although its clean-data macro-F1 was lower. Without bone type at inference, auxiliary anatomy supervision improved macro-F1 from 0.5620 +/- 0.0330 to 0.5899 +/- 0.0289. Conclusions: Structured context improves fracture classification, and consistency-aware gating limits harm from mismatched metadata. The observed clean-performance-robustness trade-off and the absence of patient-level identifiers motivate external and prospective validation.
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References · 5
- 2016Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localizationcited by 6,733
- 2017On Calibration of Modern Neural Networkscited by 4,960
- 2022A ConvNet for the 2020scited by 3,579
- 2022MedFuse: Multi-modal fusion with clinical time-series data and chest X-ray imagescited by 54
- 2023Missing-modality Enabled Multi-modal Fusion Architecture for Medical Datacited by 8
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